Klaus T. Wanner studied Chemistry and Pharmacy in Munich and obtained a PhD in Pharmaceutical Chemistry in 1983. He was a postdoctoral fellow in the research group of A. I. Meyers at Colorado State University before taking up a faculty position at the Free University of Berlin. Since 1994, He is a full professor for Pharmaceutical Chemistry at the University of Munich. His main interest is in ligand and inhibitor design for GABA receptors and transporters, as well as in stereochemical aspects of structure-activity relationships. Georg C. Hofner studied Pharmacy at the University of Munich and obtained a PhD in Pharmaceutical Chemistry in 1989. He is a specialist on screening technology and is currently supervising the biological assay unit of the Centre of Drug Research at the University of Munich.

"For those readers who are not familiar with mass spectrometry..."Lebensmittel & Biotechnologie(March 2007)

• Mass Spectrometry in Bioanalysis -Methods, Principles and InstrumentationDrug Screening Using Gel Permeation Chromatography Spin Columns Coupled with ESI-MSALIS: An Affinity Selection-Mass Spectrometry System for the Discovery and Characterization of Protein-Ligand InteractionsLibrary Screening Using Ultrafiltration and Mass SpectrometryContinuous-Flow Systems for Ligand Binding and Enzyme Inhibition Assays Based on Mass SpectrometryFrontal Affinity Chromatography -Mass Spectrometry for Ligand Discovery and CharacterizationMS-Binding Assays - an Alternative to Radioligand BindingLaser Desorption Assays -MALDI-MS, DIOS-MS, and SAMDI-MSTethering: Fragment-Based Drug Discovery by Mass SpectrometryInterrogation of Noncovalent Complexes by ESI-MS: A Powerful Platform for High Throughput Drug DiscoveryQuantification of Protein-Ligand Interactions in Solution by H/D Exchange (PLIMSTEX)Protein-Targeting Drug Discovery Guided by Hydrogen/Deuterium Exchange Mass Spectrometry (DXMS)Mass Spectrometry in Early Pharmacokinetic Investigations

Klaus T. Wanner studied Chemistry and Pharmacy in Munich and obtained a PhD in Pharmaceutical Chemistry in 1983. He was a postdoctoral fellow in the research group of A. I. Meyers at Colorado State University before taking up a faculty position at the Free University of Berlin. Since 1994, He is a full professor for Pharmaceutical Chemistry at the University of Munich. His main interest is in ligand and inhibitor design for GABA receptors and transporters, as well as in stereochemical aspects of structure-activity relationships. Georg C. Hofner studied Pharmacy at the University of Munich and obtained a PhD in Pharmaceutical Chemistry in 1989. He is a specialist on screening technology and is currently supervising the biological assay unit of the Centre of Drug Research at the University of Munich.

"For those readers who are not familiar with mass spectrometry..."Lebensmittel & Biotechnologie(March 2007)

• Mass Spectrometry in Bioanalysis -Methods, Principles and InstrumentationDrug Screening Using Gel Permeation Chromatography Spin Columns Coupled with ESI-MSALIS: An Affinity Selection-Mass Spectrometry System for the Discovery and Characterization of Protein-Ligand InteractionsLibrary Screening Using Ultrafiltration and Mass SpectrometryContinuous-Flow Systems for Ligand Binding and Enzyme Inhibition Assays Based on Mass SpectrometryFrontal Affinity Chromatography -Mass Spectrometry for Ligand Discovery and CharacterizationMS-Binding Assays - an Alternative to Radioligand BindingLaser Desorption Assays -MALDI-MS, DIOS-MS, and SAMDI-MSTethering: Fragment-Based Drug Discovery by Mass SpectrometryInterrogation of Noncovalent Complexes by ESI-MS: A Powerful Platform for High Throughput Drug DiscoveryQuantification of Protein-Ligand Interactions in Solution by H/D Exchange (PLIMSTEX)Protein-Targeting Drug Discovery Guided by Hydrogen/Deuterium Exchange Mass Spectrometry (DXMS)Mass Spectrometry in Early Pharmacokinetic Investigations

Klaus T. Wanner studied Chemistry and Pharmacy in Munich and obtained a PhD in Pharmaceutical Chemistry in 1983. He was a postdoctoral fellow in the research group of A. I. Meyers at Colorado State University before taking up a faculty position at the Free University of Berlin. Since 1994, He is a full professor for Pharmaceutical Chemistry at the University of Munich. His main interest is in ligand and inhibitor design for GABA receptors and transporters, as well as in stereochemical aspects of structure-activity relationships. Georg C. Hofner studied Pharmacy at the University of Munich and obtained a PhD in Pharmaceutical Chemistry in 1989. He is a specialist on screening technology and is currently supervising the biological assay unit of the Centre of Drug Research at the University of Munich.

"For those readers who are not familiar with mass spectrometry..."Lebensmittel & Biotechnologie(March 2007)

• Mass Spectrometry in Bioanalysis -Methods, Principles and InstrumentationDrug Screening Using Gel Permeation Chromatography Spin Columns Coupled with ESI-MSALIS: An Affinity Selection-Mass Spectrometry System for the Discovery and Characterization of Protein-Ligand InteractionsLibrary Screening Using Ultrafiltration and Mass SpectrometryContinuous-Flow Systems for Ligand Binding and Enzyme Inhibition Assays Based on Mass SpectrometryFrontal Affinity Chromatography -Mass Spectrometry for Ligand Discovery and CharacterizationMS-Binding Assays - an Alternative to Radioligand BindingLaser Desorption Assays -MALDI-MS, DIOS-MS, and SAMDI-MSTethering: Fragment-Based Drug Discovery by Mass SpectrometryInterrogation of Noncovalent Complexes by ESI-MS: A Powerful Platform for High Throughput Drug DiscoveryQuantification of Protein-Ligand Interactions in Solution by H/D Exchange (PLIMSTEX)Protein-Targeting Drug Discovery Guided by Hydrogen/Deuterium Exchange Mass Spectrometry (DXMS)Mass Spectrometry in Early Pharmacokinetic Investigations