Smart Gas Diagnostics and Therapy

Integrate gas sensing with therapeutic delivery for precision medicine Medical gases such as NO, CO, H2S, and H2 serve as pivotal regulators of cellular signaling, yet translating gas-phase diagnostics into closed-loop therapeutic systems remains a formidable challenge. Smart Gas Diagnostics and Therapy: Decoding Molecular Signals for Precision Healthcare systematically connects gas sensing technologies with gas-mediated therapeutics across four thematic parts, spanning endogenous gas physiology, advanced sensor materials, emerging detection paradigms, and integrated theranostic platforms for antibacterial, antitumor, and regenerative applications. Organized around a material-to-system co-design framework, the book details sensor architectures built on oxide semiconductors, MXenes, MOFs, and gel nanocomposites, emphasizing selectivity, sensitivity, and stability in complex biological environments. Coverage extends to organic transistor-based sensors, low-voltage wireless systems, triboelectric nanogenerators, surface-enhanced Raman techniques, and AI-driven electronic nose platforms. Chapters on gas-releasing nanomaterials and targeted delivery address clinical scalability and point-of-care deployment. Readers will also find: Physiological roles and signaling pathways of endogenous gases including NO, CO2, H2S, and volatile organic compound biomarkers in health and diseaseDesign principles for breath sensors optimized for selectivity, sensitivity, and stability in complex biological environments such as breath and wound exhalationSelf-powered triboelectric sensor architectures and catalytic tumor microenvironment modulation strategies for next-generation diagnostic and therapeutic platformsComputational tools supporting seamless translation from laboratory-scale sensor findings to scalable medical device applications in clinical settingsIntegrated theranostic platforms combining real-time gas monitoring with targeted gas-releasing nanomaterials for antibacterial, antitumor, and regenerative therapiesSmart Gas Diagnostics and Therapy serves materials scientists, electronics engineers, bioengineers, biotechnologists, cancer researchers, and sensor industry professionals working at the intersection of gas sensing and precision medicine. Graduate students and clinicians engaged in biomaterials, flexible wearable electronics, and translational healthcare will find the material-to-system design framework directly applicable to their research.