Human Substantia Nigra and Ventral Tegmental Area

A Neuroanatomical Study with Notes on Aging and Aging Diseases

AvPeter H.M.F. van Domburg,Hendrik J. ten Donkelaar

Häftad, Engelska, 1991

Del 121 i serien Advances in Anatomy, Embryology and Cell Biology

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Beskrivning

This study on the human midbrain examines how specific neuroanatomical structures are involved in the aging process and in certain degenerative diseases of the nervous system.

Produktinformation

Utgivningsdatum:1991-01-14
Mått:170 x 242 x 9 mm
Vikt:267 g
Format:Häftad
Språk:Engelska
Serie:Advances in Anatomy, Embryology and Cell Biology
Antal sidor:132
Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:9783540528234

Utforska kategorier

Anatomi inom Medicin
Neurologi och klinisk neurofysiologi inom Medicin

Innehållsförteckning

1 Introduction.- 2 Materials and Techniques.- 2.1 Cytoarchitectonic Analysis.- 2.2 Quantitative Analysis.- 2.3 Immunohistochemical Procedures.- 2.4 Neuropathological Procedures.- 3 Comparative and Developmental Notes.- 3.1 The SN and VTA in Lower Tetrapods.- 3.2 The Mammalian SN and VTA.- 3.3 Development of the SN and VTA.- 4 The Human Substantia Nigra and Ventral Tegmental Area.- 4.1 Introduction.- 4.2 Cytological Features.- 4.3 Cytoarchitectonic Subdivision.- 4.4 Chemoarchitecture.- 4.5 Fiber Connections of the Primate SN Complex.- 4.6 A Model of Human Nigral Organization.- 5 Neuropathological Aspects.- 5.1 Introduction.- 5.2 Involvement of the SN and VTA in Basal Ganglia Diseases.- 5.3 Involvement of the SN and VTA in AD.- 6 Quantitative Aspects.- 6.1 Introduction.- 6.2 Age-Related Neuronal Loss.- 6.3 Neuronal Loss in the SN and VTA in AD and PD.- 7 Functional and Pathophysiological Considerations.- 7.1 Lesion Studies on the SN.- 7.2 Some Functional and Pathophysiological Aspects of Mesencephalic DAergic Projections.- 7.3 The Involvement of the SN and VTA in AD and PD.- 8 Summary.- Acknowledgements.- References.