New Trends in Haemostasis

Coagulation Proteins, Endothelium, and Tissue Factors

AvJob Harenberg,Dieter L. Heene

Häftad, Engelska, 1990

Del i serien Sitzungsberichte der Heidelberger Akademie der Wissenschaften

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Beskrivning

To give an update in the field of haemostasis scientists andclinicians fromoverseas and European countries met to dis-cuss the new trends in pathophysiology and clinical impli-cations. This book is devoted to the interactions of endo-thelial functions, tissue factors, coagulation inhibitorsand haemostasis as well as detection and prophylaxis ofthromboembolism. Data are presented of significant new re-search work on molecular and clinical approaches to diseasesin haemostasis.

Produktinformation

Utgivningsdatum:1990-12-14
Mått:170 x 242 x 16 mm
Vikt:491 g
Format:Häftad
Språk:Engelska
Serie:Sitzungsberichte der Heidelberger Akademie der Wissenschaften
Antal sidor:270
Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:9783540532750

Utforska kategorier

Hematologi inom Medicin
Anatomi inom Medicin

Innehållsförteckning

Endothelial Functions and Haemostasis.- Structure, Shape and Function of Glycosaminoglycans.- Structure and Metabolism of Glycosaminoglycans.- Fibrin Polymerization and Its Role in Regulating Haemostasis.- Function of von Willebrand Factor in Plasma.- Biosynthesis and Assembly of the Factor VIII — von Willebrand Factor Complex.- Modulation of Endothelial Cell Function by Hypoxia: Perturbation of Barrier and Anticoagulant Function and Induction of a Novel Procoagulant Activity.- Tissue Factors and Endothelium.- Platelet Adhesion; A Concerted Action of Hemodynamic and Biochemical Processes.- Modulation of Endothelial Functions by Advanced Glycosylation End Products.- Procogulant Activities of Leukocytes.- Cytokine Induced Stimulation of Endothelial Cells in Vitro.- Anti-Platelet Treatment of Metastasis.- The Molecular Anatomy of Vitronectin as Extracellular Regulator Protein: Multifunctional Properties of the Heparin-Binding Domain.- Mode of Action of Annexin V (Vascular Anticoagulant Alpha), A Protein Synthesized by the Vessel Wall.- Coagulation Inhibitors and Haemostasis.- Clinical Pharmacologal Profile of Low Molecular Weight Heparins.- Anticoagulant Actions of Sulphated Polysaccharides.- Development of Synthetic Proteinase Inhibitors as Anticoagulant Agents.- Antithrombin and Its Deficiency States.- “New” Coagulation Inhibitors.- Biological Function of Vitamin K Antagonists.- Plasminogen Activator Inhibitors: Biological Effects.- Fibrin-Specific Clot Lysis with Single Chain Urokinase-Type Plasminogen Activator (scu-PA).- Antibody — Mediated Thrombolysis: Promise and Problems.- Thromboembolism: Detection and Prophylaxis.- Causation and Prevention of Coronary Thrombosis: Present Situation.- Non-Invasiva Diagnostic Techniques in Deep Vein Thrombosis.- Evaluationof the Bleeding Effects of Antithrombotic Drugs.- List of Participants.- List of Sponsors.