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23 produkter
23 produkter
2 163 kr
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Cardiovascular drug therapy has markedly progressed in the recent decades. Not only have new drugs been introduced to clinical practice, but new classes of drugs have been developed. While in 1960 the practicing cardiolo gist had a selection of about only ten drugs, in 1987 about 150 drugs are routinely used in cardiovascular diseases. Elderly patients, however, usually do not enjoy the full benefit of this progress. This might be due to lack of knowledge, a conservative approach, or the worldwide tendency not to try new drugs in the elderly. It is now clear that the majority of patients that will be treated in car diovascular clinics will be, in the near future, elderly patients. Even now, elderly patients form about one-third of the patients with cardiovascular diseases. These patients are approached, however, according to criteria devel oped for younger populations. This is despite the fact that elderly patients differ from younger ones in most aspects, including pathology, epidemiol ogy, pathophysiology, diagnostic approach, management, pharmacology, pharmacokinetics, rehabilitation, and supportive treatment. It is the purpose of this book to present to the clinician all drugs with which there is clinical experience in the elderly or which might be potentially useful for the elderly with cardiovascular diseases. The data are presented without the authors taking a position. This should allow the clinicians to make their own selection and individualize treatment, vii viii Preface based on a wide data base. Comparative data are presented only when specific comparative studies were performed.
2 163 kr
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Cardiovascular drug therapy has markedly progressed in the recent decades. Not only have new drugs been introduced to clinical practice, but new classes of drugs have been developed. While in 1960 the practicing cardiolo gist had a selection of about only ten drugs, in 1987 about 150 drugs are routinely used in cardiovascular diseases. Elderly patients, however, usually do not enjoy the full benefit of this progress. This might be due to lack of knowledge, a conservative approach, or the worldwide tendency not to try new drugs in the elderly. It is now clear that the majority of patients that will be treated in car diovascular clinics will be, in the near future, elderly patients. Even now, elderly patients form about one-third of the patients with cardiovascular diseases. These patients are approached, however, according to criteria devel oped for younger populations. This is despite the fact that elderly patients differ from younger ones in most aspects, including pathology, epidemiol ogy, pathophysiology, diagnostic approach, management, pharmacology, pharmacokinetics, rehabilitation, and supportive treatment. It is the purpose of this book to present to the clinician all drugs with which there is clinical experience in the elderly or which might be potentially useful for the elderly with cardiovascular diseases. The data are presented without the authors taking a position. This should allow the clinicians to make their own selection and individualize treatment, vii viii Preface based on a wide data base. Comparative data are presented only when specific comparative studies were performed.
2 480 kr
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Der Stoffwechsel der Plasmalipoproteine und seine Bedeutung für die Pathogenese der Arteriosklerose
Vorgetragen in der Sitzung vom 6. Juli 1985
Häftad, Tyska, 1986
567 kr
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1 064 kr
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The limited resources available for chemical analyses of components of interest in food has forced scientists to bor row data from published food composition works of other countries. Due to language barriers, this is often undertaken without due knowledge of the background and the instruc tions for use. This collection of introductions, translated in to English, of frequently cited, published food tables has been compiled with the assistance and cooperation of many collaborators throughout the world. We hope that the result will facilitate a more appropriate and extensive use of foreign food tables for scientific purposes. Lenore Arab Marion Wittler Gotthard Schettler Introduction The following is a compilation of the introductory material included in the most recent edition of 19 of the published food composition tables of 14 European countries. In most cases these translations were graciously provided by the pro ducers of the tables or native-speaking people working closely with the information concerned. Recognition of the authors is given on each of the title pages. The title page also includes full publication details of the various tables and summary information on the number of foods contained in the latest edition as well as the number of food components within the tables. It should be noted that a complete list of components is not always given for each food, either because the component is not present, or data is not avail able.
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The outstanding contributions to this volume are designed to shed light on some fields of cell biology and cellular pathology, including newly observed phenomena of cell-cell interactions, which might be applicable in studying the pathological process of atherosclerosis. The topics included cover: lipoproteins and lipoprotein receptors; growth factors; endocytosis and exocytosis; ONC Genes and proliferative disease; white blood cells; prostaglandins and leukotrienes; and the biology of smooth muscle and endothelium. The volume provides a complete summary of the most important developments in the field with great impact for arteriosclerosis research.
1 095 kr
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Das Spektrum der in den westlichen Industrienationen filhren- den Krankheiten und der darauf basierenden Thdesursachen hat sich in den letzten J ahrzehnten gewandelt. Wahrend frliher die Infektionskrankheiten und speziell die Thberkulose den hochsten Todeszoll forderten, sind in den Jahrzehnten nach dem zweiten Weltkrieg mit steigendem Wohlstand die Herz- und GefaBkrankheiten an die erste Stelle gerlickt. Trotz gewis- ser Erfolge in der Pravention in einigen Uindern wie z. B. in den USA, Kanada, Australien; aber auch in einigen Gebieten West- europas, in denen die Zahl der tOdlichen Hirnschlage und Herzinfarkte inzwischen wieder rlicklaufig ist, wird die Spit- zenposition in der Todesursachenstatistik hier auch weiterhin von diesen Krankheiten eingenommen. In anderen Uindern wie z. B. in Osteuropanehmen die Erkrankungsraten weiter zu. Wenn man sich fragt, was getan werden kann, urn weitere Er- fqlge auf diesem Gebiet zu erzielen, dann ist ein Blick in die Lander des Fernen Ostens hilfreich. In der Volksrepublik Chi- na undin J apanliegt die Sterblichkeit an koronarer Herzkrank- heit bzw. an Herzinfarkten flinf- bis zehnmal niedriger als in der Bundesrepublik Deutschland.Arteriosklerotische Durch- blutungsstorungen der unteren Extremitaten, auch diabeti- sche GefaBerkrankungen kommen dort kaum vor. Vergleicht man die Lebensweise der Bevolkerung in diesen Uindern mit den Verhaltnissen in den westlichen Industriena- tionen, so fallenerhebliche Unterschiedeinder Ernahrungauf. Wahrend in China Fleisch und Molkereiprodukte in deutlich geringeren Mengen als bei uns verzehrt werden, besteht der Hauptanteil der Ernahrung aus einer an pflanzlichem EiweiB und Schlackenstoffen reichen Kost.
Wachstumsfaktoren und Onkogenprodukte bei Entstehung und Regression der Arteriosklerose
Häftad, Tyska, 1988
567 kr
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Die Pathogenese der Arteriosklerose ist immer noch weitgehend ungeklärt. In jüngster Zeit zeichnet sich jedoch ein wesentlicher Fortschritt im Verständnis der zugrundeliegenden kausalen Ereignisse ab. Das Entstehen arteriosklerotischer Läsionen beruht mit hoher Wahrscheinlichkeit auf einer Fehlsteuerung der interzellulären Kommunikation, die zum Verlust der Gefäßwandhomöostase führt. In einem komplexen Wechselspiel sind hieran hauptsächlich Wachstums- und Differenzierungsfaktoren beteiligt, deren biologische Funktion derzeit intensiv erforscht wird. Dieses Buch enthält eine Bestandsaufnahme über die zentrale Rolle dieser Wachstums- und Differenzierungsfaktoren beim Entstehen der Arteriosklerose. Es vermittelt Anstöße für grundlegende Forschungen auf diesem Gebiet, um zu neuen Therapiekonzepten im Kampf gegen die Arteriosklerose zu gelangen.
551 kr
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Initiated in 1975, the Eberbach/Wiesloch Study is a prospective preventive study modeled after the Cardiovascular Comprehensive Community Central Programme of the WHO, with the aim of lowering the incidence of cardiac infarctions in a population representative of that of the Federal Republic of Germany. Part of the study is devoted to a description of smoking habits, and in particular, of the effect of cigarette smoking on plasma lipid and lipoprotein levels. Important components of this investigation were the inclusion of plasma levels of cotinine (a stable metabolite of nicotine and the only precise parameter of cigarette consumption), as well as the correlation of cotinine with other plasma parameters. Not only are these studies unique in the Federal Republic of Germany, but they also provide significant insight into the development of arteriosclerosis in connection with the established risk factors of smoking and hyperlipidemia. The data collected point to a considerable influence of smoking behavior on plasma lipid protein parameters.
Thiaminzufuhr und Thiaminstatus der Bevölkerung in der Bundesrepublik Deutschland
Häftad, Tyska, 1988
550 kr
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542 kr
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Der Bericht präsentiert die Ergebnisse der Heidelberger Männer-Studie, der Heidelberger Frauen-Studie und der Ernährungs- und Gesundheitsstudie. Ausführlich wird die Eisenversorgung für repräsentative Bevölkerungsgruppen in der Bundesrepublik Deutschland analysiert. Die Autoren kommen zu einer überraschend günstigen Beurteilung der Eisenversorgung in der Bevölkerung. Potentielle und reale Risikogruppen werden identifiziert. Weiterhin werden Einflußfaktoren auf die Eisenversorgung und Eisenzufuhr wie Eßgewohnheiten, Alkoholkonsum, Rauchen, Einnahme von Kontrazeptiva und körperliche Aktivität auf ihre Bedeutung hin untersucht und abgehandelt.
567 kr
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1 095 kr
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A high-level text on the molecular and genetic aspects of human ageing with reference to cognitive functions and age-related diseases.
New Trends in Haemostasis
Coagulation Proteins, Endothelium, and Tissue Factors
Häftad, Engelska, 1990
1 095 kr
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To give an update in the field of haemostasis, scientists and clinicians from overseas and European countries met to discuss the new trends in pathophysiology and clinical implications. This book is devoted to the interactions of endothelial functions, tissue factors, coagulation inhibitors and haemostasis as well as detection and prophylaxis of thromboembolism. Data of new research work on molecular and clinical approaches to diseases in haemostasis is presented. This book of proceedings on haemostasiology and angiology is intended for reseachers and clinicians.
Gesundheitsrisiken in der Industriegesellschaft
Vorgetragen in der Sitzung vom 1. Dezember 1990
Häftad, Tyska, 1991
567 kr
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Die Erkrankungsrisiken f}r Schlaganf{lle, Herzinfarkte und Krebs sind in europ{ischen L{ndern sehr unterschiedlich. Der Zusammenhang zwischen Risikofaktoren wie Rauchen, Alkohol- konsum, falscher Ern{hrung und Lebenserwartung in verschie- denen Regionen f}hrt zu einer gesundheitspolitischen Dis- kussion um Vorsorgeuntersuchungen und Pr{vention.
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The essays in this book discuss the role that chemicalagents in the environment play in the development of cancer.Thus, it gives information toimprove our understanding ofcarcinogenesis and how to prevent it. The essays wereoriginally presented at an international symposium.
Baseline Evaluation
CINDI Countrywide Integrated Noncommunicable Diseases Intervention Programme
Häftad, Engelska, 1991
551 kr
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CINDI is a European intervention programme against major noncommunicable diseases (NCDs). 12 European countries, Canada and Israel participate in the programme, which is co-ordinated by the World Health Organization. This book describes the situation in these countries prior to the start of the programme. Trends in the premature mortality of some major NCDs are given as well as the prevalence of risk factors for NCDs in the population (high blood cholesterol, high blood pressure, overweight, smoking). The results presented stress the necessity of a countrywide integrated approach. NCDs account for two-thirds of premature deaths in the CINDI countries, and approximately 70% of the adult population is at risk.
567 kr
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Das vorliegende Buch enth{lt die Proceedings einer Tagung der Konferenz der Akademien der Wissenschaften in der Bundesrepublik Deutschland. Ziel der Tagung war es, M|glich- keiten, Hindernisse und Chancen der Zusammenarbeit zwischen Industrie und Wissenschaft sowie die Rolle der Politik, Gesetzgebung und \ffentlichkeit grunds{tzlich zu diskutieren und neue Anregungen unter Ber}cksichtigung der besonderen aktuellen Situation in Deutschland zu geben. In dem Buch wurden Diskussionsbeitr{ge von Vertretern von Wissenschaftsinstitutionen, der forschenden Industrie, den Medien und Wissenschaftsphilosophen mit aufgenommen. Dabei ging es nicht nur um Formen der Forschungsf|rderung, sondern auch um die Darstellung der Zusammenarbeit von Wissenschaft und Industrie im Lichte der \ffentlichkeit.
Cellular Metabolism of the Arterial Wall and Central Nervous System
Selected Aspects
Häftad, Engelska, 1993
1 095 kr
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International experts review the molecular biology of ion channels, diseases of the central nervous system including Alzheimer's disease, the molecular biology of atherogenesis, plasma lipproteins, lipid transport, long chain fatty acid transport and metabolism, and lipoprotein receptors. Future directions and perspectives and common features in these important areas are discussed.
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In 1993 three institutes belonging respectively to the Heidelberg Academy for Humanities and Sciences, to the Russian Academy of Sciences and to the Russian Academy of Medical Sciences, launched a co-operative research project. The main aim of the project is to develop mathematical methodologies needed for better information support in health policy decision-making in the area of primary health care provision for the Russian populations affected by radiation due to the Chernobyl accident. This work describes the general mathematical approaches to the project and the given conditions of the registry.
770 kr
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1 095 kr
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Major advances have been made in the understanding of the molecular mechanisms of atherosclerosis, the disease that still affects more than 50 percent of the population in the highly industrialized countries. This volume covers the most recent advances in the treatment of hyperlipidemia. It represents a necessary update because molecular mechanisms of atherogenesis have been discovered in the past few years and their molecular mechanisms of action identified. Extensively treated are the molecular mechanisms of disease etiology of arteriosclerosis in relation to the major risk factor "hyperlipidemia", rationale for more effective treatment of this disease by dietary means, the treatment of associated or causing diseases, and the treatment using hypolipidemic drugs.
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Numerous new and important findings relating to the reconstruction of disturbed circulatory conditions in the coronary area are reported in this book. Fundamental aspects of therapeutic and prophylactic possibilities are covered in detail. Recommendations are then made to practitioners and clinicians for their everyday work. Critical standards for the indications and risks of the recommended procedures are given. Particular emphasis is laid on the possibilities for revascularization by means of dissolution of blood thrombi. The book aims to present top-level guidance to the pros and cons of reconstructive measures in coronary disorders.