Oncogenes Meet Metabolism

From Deregulated Genes to a Broader Understanding of Tumour Physiology

AvGuido Kroemer,Dominik Mumberg

Häftad, Engelska, 2010

Del i serien Ernst Schering Foundation Symposium Proceedings

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Beskrivning

In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions.

Produktinformation

Utgivningsdatum:2010-11-30
Mått:130 x 210 x 16 mm
Vikt:326 g
Format:Häftad
Språk:Engelska
Serie:Ernst Schering Foundation Symposium Proceedings
Antal sidor:265
Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:9783642098406

Utforska kategorier

Fysiologi inom Medicin
Analytisk kemi inom Naturvetenskap och teknik
Onkologi inom Medicin

Innehållsförteckning

Mitochondria and Cancer.- Role of the Metabolic Stress Responses of Apoptosis and Autophagy in Tumor Suppression.- The Interplay Between MYC and HIF in the Warburg Effect.- Using Metabolomics to Monitor Anticancer Drugs.- Biomarker Discovery for Drug Development and Translational Medicine Using Metabonomics.- Pyruvate Kinase Type M2: A Key Regulator Within the Tumour Metabolome and a Tool for Metabolic Profiling of Tumours.- Molecular Imaging of Tumor Metabolism and Apoptosis.- Minimally Invasive Biomarkers for Therapy Monitoring.- Use of Metabolic Pathway Flux Information in Anticancer Drug Design.- Cancer Diagnostics Using 1H-NMR-Based Metabonomics.- Human Metabolic Phenotyping and Metabolome Wide Association Studies.- Defining Personal Nutrition and Metabolic Health Through Metabonomics.