Immobilized Enzymes in Medicine

AvVladimir P. Torchilin,J.A. Kellen

Häftad, Engelska, 2011

Del 11 i serien Progress in Clinical Biochemistry and Medicine

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Beskrivning

The application of immobilized enzymes in medicine is the main objective of this book. The author reviews natural and synthetic carriers for enzyme immobilization, chemistry of enzyme binding, and in-vitro and in-vivo properties of immobilized enzymes. Four chapters are dedicated to clinical use of immobilized enzymes.

Produktinformation

Utgivningsdatum:2011-12-13
Mått:155 x 235 x 13 mm
Vikt:341 g
Format:Häftad
Språk:Engelska
Serie:Progress in Clinical Biochemistry and Medicine
Antal sidor:206
Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:9783642758232

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Farmakologi inom Medicin
Klinisk medicin och internmedicin inom Medicin

Innehållsförteckning

1 Introduction.- 2 Enzymes in Medicine: Advantages and Disadvantages.- 2.1 Native Enzymes in Therapy and Clinical Analysis.- 2.2 Difficulties Connected with Enzyme Application in Medicine...- 2.3 How the Immobilization can Help.- 3 Immobilization of Therapeutic Enzymes.- 3.1 General Principles of Enzyme Stabilization and Immobilization.- 3.2 The Peculiarities of Enzyme Immobilization for Medical Use. Carriers and Immobilization Methods Required.- 3.3 The Fate of Immobilized Enzymes in the Body.- 3.4 Principal Types of Immobilized Enzymes in Medicine.- 4 Therapeutic Immobilized Enzymes for Parenteral Application.- 4.1 Preparations Intended for Prolonged Circulation in the Body.- 4.2 Insoluble Immobilized Enzymes for Local Application.- 4.3 Immobilization Principles and Drug Targeting.- 5 Immobilized Enzymes for Extracorporeal Application.- 5.1 Immobilized Enzymes in Extracorporeal Systems.- 5.2 Dressing and Drainage Materials Containing Immobilized Enzymes; Films, Ointments and Powders with Immobilized Enzymes in the Treatment of Wounds, Ulcers and Burns.- 6 Immobilized Enzymes in Clinical Analysis.- 6.1 Enzyme Electrodes.- 6.2 Enzyme Immunoassay.- 6.3 Immobilized Bioluminiscent Systems.- 6.4 Reactors with Immobilized Enzymes; Miscellaneous.- 7 Conclusion.- 8 References.

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