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Beskrivning
Some of the current concepts used in transgenic research, an increasingly important tool to study the regulation and function of genes, are illustrated in this book.
1 The Human Renin-Angiotensin System in Transgenic Rats — New Tools for Antihypertensive Therapy.- 2 Probing the Genetics of Atherosclerosis in Transgenic Mice.- 3 The PrP-less Mouse: A Tool for Prion Research.- 4 The Carboxyterminal Fragment of the Alzheimer Amyloid Protein Precursor Causes Neurodegeneration In Vivo.- 5 Transgenic Models of Chronic Arthritis and of Systemic Tumour Necrosis Factor-Mediated Disease in Mice Expressing Human Tumour Necrosis Factor.- 6 Mammary Neoplasia in Mouse Mammary Tumor Virus-Transforming Growth Factor ? Transgenic Mice.- 7 Exploring the Pathogenic Potential of c-fos, Polyoma Middle T and Human Foamy Virus in Transgenic Mice.- 8 Transgenic Animals as Bioreactors for Therapeutic and Nutritional Proteins.- 9 Targeted Inactivation of the Muscle Regulatory Genes Myf-5 and MyoD: Effect on Muscle and Skeletal Development.
