Activating and Inhibitory Immunoglobulin-like Receptors

Häftad, Engelska, 2012

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Beskrivning

This volume is the first attempt to summarize and highlight all known aspects of immunoglobulin-like receptors, providing a topical overview of the roles and characteristic features of the immunoglobulin-like receptors and related molecules in the immune system.

Produktinformation

Utgivningsdatum:2012-11-15
Mått:155 x 235 x 15 mm
Vikt:400 g
Format:Häftad
Språk:Engelska
Antal sidor:246
Förlag:Springer Verlag, Japan
ISBN:9784431679592

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik

Innehållsförteckning

Fc receptors: Activation-inhibition receptor pairing.- Phylogeny of Paired Ig-like Receptors.- Genomic organization of the ILT11 gene, a novel member of the Leukocyte Receptor Cluster (LRC).- Regulated expression of non-polymorphic gp49 molecules on mouse natural killer cells.- Regulation of human Fc?R gene expression.- Molecular recognition by Ig-like receptors, KIRs and Fc?Rs.- Ig modules as discrete structural units to exploit functional and structural aspects of Ig-like receptors.- Structural studies on the leukocyte co-stimulatory molecule, B7-1.- ITIM-bearing receptors in platelets.- Identification of Fc?/u receptor expressed on B lymphocytes and macrophages.- Functional characterization of mouse CD94 by using a novel monoclonal antibody.- Interaction of human cytomegalovirus glycoproteins with immunoreceptors.- Function of gp49A in mast cell activation.- The Fc receptor family structure based strategies for the development of anti-inflammatory drugs.- The mouse gp49 family.- Regulation of B-cell antigen receptor signaling by CD72.- A role for the SH2-containing inositol phosphatase in the biology of natural killer cells and stem cells.- SHIP 1-mediated negative regulation of cell activation and proliferation by Fc?RIIB.- The preBCR signaling through Igß regulates locus accessibility for ordered immunoglobulin gene rearrangements.- Regulation of phospolipase C-?2 and phosphoinositide 3-kinase by adaptor proteins in B cells.- Fc receptor signaling during phagocytosis.- Molecular mechanism of paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal.- IgE stabilizes its high affinity receptor (Fc?RI) on mast cells in vitro and ex vivo: The mechanism of IgE-mediated Fc?RI up-regulation and its physiological meaning.- Autoimmune arthritis andGoodpasture’s syndrome induced in Fe? receptor-deficient mice.- Receptors involved in human NK cell activation in the process of natural cytotoxicity.- The regulation of PD-1/PD-L1 pathway and autoimmune diseases.- Identification of the functional recognition site on MHC class I for a NK cell lectin-like receptor.- Characterization of Tml cells, a NKR+ subset of memory-phenotype CD8+ T cells.- How do killer cell Ig-like receptors inhibit natural killer cells?.