The globalization processes in tourism, the fast and constant change of the tourist market, the more intensive competition between the tourist areas require faster and more flexible changes, reactions on behalf of the macro- and micro environment of tourism. That is the reason why the current management and operation process of tourism require some changes, they need to be renewed. The present structure of tourism management and operation get revaluated, it is replaced by the modern tourism management and operation system, the regional and organizational system of destination management. It is hoped that his book will not only meet the requirements of students but will also be useful as a guide to the academic professionals.