Developmental Origins of Health and Disease (DOHaD)

From Biological Basis to Clinical Significance

AvTakeo Kubota,Hideoki Fukuoka

Häftad, Engelska, 2019

Del 1012 i serien Advances in Experimental Medicine and Biology

1 763 kr

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Beskrivning

This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period.

Produktinformation

Utgivningsdatum:2019-02-05
Mått:178 x 254 x 6 mm
Vikt:240 g
Format:Häftad
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:95
Förlag:Springer Verlag, Singapore
ISBN:9789811338564

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Mer om författaren

Takeo KubotaFaculty of Child Studies, Seitoku University, Chiba, JapanHideoki Fukuoka Research Institute for Science and Engineering, Waseda University, Tokyo, Japan

Innehållsförteckning

Part 1 Biological Basis.- One carbon metabolism and lipid metabolism in DOHaD.- Novel models of epigenetic gene regulation in the nutritional environment.- Epigenetic switching and neonatal nutritional environment.- Part 2 Disease and environment.- Developmental Origins of Non-Alcoholic Fatty Liver Disease (NAFLD).- Fetal origins of hypertension.- Involvement of noncoding RNAs in stress-related neuropsychiatric diseases caused by DOCaD theory.- Part 3 Transgenerational mechanism and its consequences.- Placental development and nutritional environment.- Risk of neurodevelopmental disease by paternal aging: a possible influence of epigenetic alteration in sperm.- Part 4 Clinical Significance.- Preemptive epigenetic medicine based on fetal programming.