DJ-1/PARK7 Protein

Parkinson’s Disease, Cancer and Oxidative Stress-Induced Diseases

AvHiroyoshi Ariga,Sanae M. M. Iguchi-Ariga

Häftad, Engelska, 2018

Del i serien Advances in Experimental Medicine and Biology

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Beskrivning

This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases. Those chapters present the roles of DJ-1 in various oxidative stress-related diseases such as neurodegenerative diseases, as well as cancer, diabetes, and fertility.

Produktinformation

Utgivningsdatum:2018-12-12
Mått:155 x 235 x 12 mm
Vikt:401 g
Format:Häftad
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:222
Förlag:Springer Verlag, Singapore
ISBN:9789811349089

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik

Mer om författaren

Hiroyoshi ArigaFaculty of Pharmaceutical Sciences, Hokkaido UniversitySapporo, JapanSanae M.M. Iguchi‐ArigaFaculty of Agriculture, Hokkaido UniversitySapporo,Japan

Innehållsförteckning

Preface.-　Chapter 1 Introduction/Overview.- Chapter 2 Structural Biology of the DJ-1 Superfamily.- Chapter 3 Expression of DJ-1 in patients with neurodegenerative diseases.- Chapter 4 DJ-1 as an oncogene and its clinical significance.- Chapter 5 Role of DJ-1 in fertilization.- Chapter 6 Anti-oxidative stress function of DJ-1.- Chapter 7 Ttranscriptional regulation of DJ-1.- Chapter 8 Regulation of Signal Transduction by DJ-1.- Chapter 9 Protein repair by DJ-1 from glycation by glyoxal and methylglyoxal.- Chapter 10 DJ-1 as a biomarker of Parkinson's disease.- Chapter 11 Roles of DJ-1 in diabetes mellitus .- Chapter 12 Therapeutic activities of DJ-1 and its binding compounds against neurodegenerative diseases.- Chapter 13 DJ-1 as an oncogene and promising target for cancer chemotherapy.