B Cells in Immunity and Tolerance

Inbunden, Engelska, 2020

Del 1254 i serien Advances in Experimental Medicine and Biology

1 683 kr

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Beskrivning

This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.

Produktinformation

Utgivningsdatum:2020-04-23
Mått:178 x 254 x 17 mm
Vikt:576 g
Format:Inbunden
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:181
Upplaga:20001
Förlag:Springer Verlag, Singapore
ISBN:9789811535314

Utforska kategorier

Onkologi inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin

Mer om författaren

Dr. Ji-Yang Wang is a professor at Department of Immunology, School of Basic Medical Sciences, Fudan University, China. He was recruited to the 1000Talents Program of Shanghai in 2013. Prof. Wang’s research focuses on B cell development, activation and differentiation, and B cell-related diseases. He has published more than 100 articles on international journals in these fields.

Innehållsförteckning

B cell development and maturation.- B cell receptor signalling.- Involvement of reactive oxygen species (ROS) in BCR signaling as a second messenger.- Germinal center reaction.- Memory B cells in local and systemic sites.- Regulation of plasma cell differentiation.- Regulation of humoral immune responses and B cell tolerance by the IgM Fc receptor.- Regulatory B cells.- Diversified IgA-bacteria interaction in gut homeostasis.- Primary antibody deficiencies.- B cell-mediated autoimmune diseases.- B cell lymphomas.