A. Rami Horowitz – författare

This book covers advanced concepts and creative ideas with regard to insect biorational control and insecticide resistance management. Some chapters present and summarize general strategies or tactics for managing insect pests such as the principles of IPM in various crop systems and biorational control of insect pests, advances in organic farming, alternative strategies for controlling orchard and field-crop pests. Other chapters cover alternative methods for controlling pests such as disruption of insect reproductive systems and utilization of semiochemicals and diatomaceous earth formulations, and developing bioacoustic methodsfor mating disruption. Another part is devoted to insecticide resistance: mechanisms and novel approaches for managing insect resistance in agriculture and in public health.

In the past, insecticide development has been guided mostly by chemo-rational and bio-rational design based on understanding of the physiology and ecology of insects and crops. A limitation in each new class of compounds is the evolution of resistance in populations of key pests, which ultimately leads to control failures. This phenomenon and the desire to produce more selective and biorational compounds serve as the driving force to develop advanced technologies for insecticide design. Among the highlights of this book are the use of nanotechnology to increase potency of available insecticides, the use of genetic engineering techniques for controlling insect pests, the development of novel insecticides that bind to unique biochemical receptors, the exploration of natural products as a source for environmentally acceptable insecticides, and the use of insect genomics and cell lines for determining biological and biochemical modes of action of new insecticides.

Among the highlights of this book is the use of novel insecticides acting on a specific site in an insect group and are compatible with natural enemies and the environment. One of such approaches is based on disrupting the activity of biochemical sites acting on transcription factors such as the Helix-Loop-Helix (bHLH) family, anti juvenile hormone (AJH) agents that target JH biosynthetic enzymes, G-protein coupled receptors (GPCR) and bursicon as a target for insect control. Another one is the biotechnology or the genetic approach such as gene silencing (RNA interference) and Bt-crops. Other sections of the book are devoted to the plant’s natural products, optical manipulation and the use of nanotechnology for improving insect control methods.