A. W. F. Edwards - Böcker
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956 kr
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In 1901 William Bateson, Professor of Biology at Cambridge, published a renewed version of a lecture which he had delivered the year before to the Royal Horticultural Society in London (reprinted in the book as an appendix). In this lecture he recognized the importance of the work completed by Gregor Mendel in 1865, and brought it to the notice of the scientific world. Upon reading Bateson's paper, Archibald Garrod realized the relevance of Mendel's laws to human disease and in 1902 introduced Mendelism to medical genetics.The first part of A Century of Mendelism in Human Genetics takes a historical perspective of the first 50 years of Mendelism, including the bitter argument between the Mendelians and the biometricians. The second part discusses human genetics since 1950, ending with a final chapter examining genetics and the future of medicine. The book considers the genetics of both single-gene and complex diseases, human cancer genetics, genetic linkage, and natural selection in human populations. Besides being of general medical significance, this book will be of particular interest to departments of genetics and of medical genetics, as well as to historians of science and medicine.
3 238 kr
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In 1901 William Bateson, Professor of Biology at Cambridge, published a renewed version of a lecture which he had delivered the year before to the Royal Horticultural Society in London (reprinted in the book as an appendix). In this lecture he recognized the importance of the work completed by Gregor Mendel in 1865, and brought it to the notice of the scientific world. Upon reading Bateson's paper, Archibald Garrod realized the relevance of Mendel's laws to human disease and in 1902 introduced Mendelism to medical genetics.The first part of A Century of Mendelism in Human Genetics takes a historical perspective of the first 50 years of Mendelism, including the bitter argument between the Mendelians and the biometricians. The second part discusses human genetics since 1950, ending with a final chapter examining genetics and the future of medicine. The book considers the genetics of both single-gene and complex diseases, human cancer genetics, genetic linkage, and natural selection in human populations. Besides being of general medical significance, this book will be of particular interest to departments of genetics and of medical genetics, as well as to historians of science and medicine.
441 kr
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This new and expanded edition of A. W. F. Edwards' classic volume on scientific inference presents his most important published articles on the subject. Edwards argues that the appropriate axiomatic basis for inductive inference is not that of probability, with its addition axiom, but that of likelihood, the concept introduced by Fisher as a measure of relative support among different hypotheses. Starting from the simplest considerations and assuming no more than a basic acquaintancewith probability theory, the author sets out to reconstruct a consistent theory of statistical inference in science. Using the likelihood approach, he explores estimation, tests of significance, randomization, experimental design, and other statistical topics. Likelihood is important reading for students and professionals in biology, mathematical sciences, and philosophy.
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Used today in spheres of life as diverse as business strategy, creative writing, medicine, computer science, and theoretical physics, Venn diagrams possess fascinating properties. The basic Venn diagram is both elegantly simple-three overlapping circles that intersect to create eight distinct areas-and conceptually innovative. Devised by English logician John Venn (1834-1923) to visually represent complex logical propositions and algebraic statements, the diagrams drew the excited interest of both scholars and the general public. In Cogwheels of the Mind, statistician and geneticist A. W. F. Edwards provides an accessible and engaging history of the Venn diagram, its reception and evolution, and its presence in such objects and images as Christian iconography, tennis balls, and flags which provide a rich source of Venn diagrams for Edwards, including those of Switzerland, Poland, and Japan (all one-set Venn diagrams), Greenland (a two-set Venn diagram), and Maryland (a three-set device).Edwards begins with a sketch of Venn's life, his discovery of the three-circle design while developing a series of lectures on symbolic logic at Cambridge University, and the publication of his find in an 1880 paper, and, more influentially, his 1881 book, Symbolic Logic. Edwards discusses the rival diagrammatic scheme invented by Charles Dodgson, better known as Lewis Carroll, who also developed a board game based on his design. The author also recreates famous Venn diagrams from history, including Winston Churchill's of 1948 depicting the mutual interests of the British Empire, a united Europe, and the English-speaking world, with the United Kingdom located at the intersection. Edwards goes on to show how different shapes can be linked together to form artistically beautiful and mathematically important, multi-set Venn diagrams, including the author's own influential Adelaide variation. And he delineates the possibilities for expanding the analytic power of these diagrams far beyond those first appreciated by Venn. Edwards even tells readers how to draw complex Venn diagrams on a spherical surface to create "Vennis balls."For anyone interested in mathematics or its history, Cogwheels of the Mind is invaluable and compelling reading.