Aarif Ali - Böcker

Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The book's chapters over the foundational aspects of pharmacogenomics, including drug metabolism, drug discovery, development, and testing, and then detail studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. This is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. However, researchers and graduate students in the related fields of genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit from the structured approach of the book.

Provides an in-depth review of pharmacogenomics and its role in drug discovery/metabolism and its clinical impactsDescribes the practice of pharmacogenomics in the treatment of diabetes, cancers, cardiovascular diseases, psychiatric disorders, pulmonary diseases, infectious, gastroenterology, and autoimmune diseasesUses a consistent chapter structure to support understanding of the fundamental concepts in the area

Biological Insights of Multi-Omics Technologies in Human Diseases provides detailed information about the basics of multi-omic technologies, including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters, this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharmaceutical, socio-ethical, and economic perspectives.The chapters are designed in a well-defined chronology such that readers will intuitively understand the central idea. This book is an ideal resource for health professionals, scientists and researchers, nutritionists, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

Explains the in-depth role of multi-omics on drug discovery/metabolism, diseases, and highlights progress in both the research and clinical areas of computation, as well as relevant implementation experience and challengesDescribes the practice of multi-omic technologies in the treatment of several diseasesIncludes practical application and machine learning approaches of multi-omics

CRISPR-Cas systems have redefined the landscape of genetic engineering, offering an unprecedented level of precision, efficiency, and versatility in genome editing. This book, titled Gene Editing by CRISPR-Cas, provides a comprehensive and well-structured approach on the historical context of genetics and gene-editing techniques leading to the groundbreaking discovery of CRISPR-Cas systems.Distinguished by its multidisciplinary scope, this volume not only delves into CRISPR-Cas systems but also examines alternative and next-generation gene-editing technologies. The book aims to inform and engage both general audience with a keen interest in science and biology, and professionals and students in related fields. By offering a balanced blend of scientific explanations and real-world applications, the book seeks to empower readers to understand the potential of CRISPR technology and its impact across diverse domains, such as medicine, agriculture, biotechnology, and diagnostics, while addressing the ethical, regulatory, and biosafety considerations essential for responsible implementation. Furthermore, this book engages in a discussion on the future directions and broader impacts of CRISPR technologies, providing valuable insights into the evolving landscape of genome engineering and its implications for scientific advancements.Key Features:This book is written in a clear and accessible manner, making complex scientific concepts understandable to a general audience without overwhelming them with technical jargonThis book provides a comprehensive exploration of the discovery and evolution of CRISPR technology, delving into the underlying science and its transformative capabilities. It serves as an excellent introduction to both the technical intricacies and the human implications of this groundbreaking technologyThis book provides an in-depth exploration of the potential uses of CRISPR across multiple domains, with a particular focus on genetic disease treatment, cancer studies, agricultural advancements, HIV, blood disorders, neurological conditions, insect biology, microbial engineering, and both infectious and non-infectious diseasesFurthermore, this book also provides critical analysis of bioethics, safety concerns, and regulatory frameworks, providing a responsible perspective on genome editing

This book discusses the molecular mechanisms, signaling pathways, and emerging technologies in wound healing. The initial chapters present wound classification and examine the important role of signaling pathways and biomarkers in tissue repair. The relationship between the skin microbiome and wound healing is also explored, emphasizing the influence of microbial communities on acute and chronic wounds. The book also explores the use of animal models in wound healing research, outlining the advantages and limitations of various species in preclinical studies. Additionally, it examines the natural and bio-based approaches, including the use of herbal remedies and animal-derived products in wound healing. Further, the book reviews the revolutionary role of artificial intelligence in wound assessment and precision medicine. Further, the book presents conventional and novel therapeutic strategies, including bioengineered materials and nanotechnology for stem cell-based treatments and extracellular matrix-based therapies. The significance of nutritional support is examined, detailing the role of macronutrients, micronutrients, and hydration in optimizing wound repair.Key FeaturesCovers the molecular mechanisms, classification, and physiological processes involved in tissue repairExamines key biological regulators and their roles in wound assessment and healing progressionHighlights the impact of microbial communities on acute and chronic wound healingDiscusses the advantages, limitations, and biomedical relevance of various animal models in wound healing studiesInvestigates the role of herbal remedies and animal-derived products in promoting wound healingThis book is intended for researchers and students of regenerative medicine, biomedical sciences, and pharmaceutical sciences.