Muneeb U Rehman – författare

Black Seeds (Nigella sativa) is a comprehensive resource covering all aspects of this medicinal plant, well-known for its positive effects in many human ailments. It has been used to promote health and fight diseases, and has been found to have antioxidant, antihypertensive, anti-diabetic, anti-inflammatory, and analgesic effects. It has also been known to have antimicrobial, anticancer, neuro-protectant, cardio protectant, immunomodulator, hepatic protectant characteristics. Thymoquinone, the active compound of the plant, also exhibits these protective qualities against many disorders. This book summarizes the effect of this plant on all the organ systems of the body. Black Seeds (Nigella sativa) is a comprehensive resource for researchers working in pharmacology, food chemistry and pharmaceutical chemistry, both in industry and academia.

A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics.

An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology.

Clinical Applications of Immunogenetics: Immunogenetics: A Molecular and Clinical Overview, Volume II provides readers with an exclusive, updated overview of scientific knowledge, achievements and findings in the field of immunogenetics. In thirteen chapters, the book gives insights in new advancements and approaches in viral and autoimmune diseases. Specific chapters are dedicated to immunogenetic mechanisms in the treatment of immune disorders, cancer, neurological and neurodegenerative disorders. In addition, other chapters cover immunogenomics in precision medicine, clinical medicine and transplantation. Finally, a special chapter, COVID-19: A novel challenge to human immune-genetic machinery, updates on thoughts surrounding the pandemic.

Proteomics: A Promising Approach for Cancer Research provides an updated overview of scientific knowledge, achievements and findings in the field of cancer proteomics. The book discusses topics such as the use of proteomics in cancer biology and drug discovery, its role in surgical oncology, applications of mass spectrometry, target proteomics, single-cell proteomics, and next-generation proteomics. In addition, it discusses proteomics and phosphor-proteomics in cancer precision medicine; translation of proteomics research into clinical application; and challenges and future developments of the field. This will be a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of proteomics in cancer research and treatment.

The field of cancer proteomics is very dynamic, with emerging trends related to clinical solutions developed in recent years, therefore this book's content helps readers get up-to-speed on the topic to easily apply learnings into their research or clinical practice.

Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The book's chapters over the foundational aspects of pharmacogenomics, including drug metabolism, drug discovery, development, and testing, and then detail studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. This is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. However, researchers and graduate students in the related fields of genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit from the structured approach of the book.

Dihydropyrimidinones as Potent Anticancer Agents gives readers a unique update on scientific knowledge, accomplishments and recent advances in the medicinal chemistry of dihydropyrimidinones in cancer treatment. Dihydropyrimidinones are known to be active scaffold and have been reported to show some exceptional results with regards to malignancies. With ever increasing knowledge and information about synthesis, pharmacology and other aspects of dihydropyrimidinones, there is need to document such information in one place. Since the field of medicinal chemistry is dynamic, with new emerging trends, it provides readily available updated information on chemistry and pharmacology aspects of dihydropyrimidinones in cancer.

This book covers everything about dihydropyrimidinones from synthesis, derivatives, mode of action and potential therapeutic targets. It will also provide insights about the clinical trials and way forward in cancer research of dihydropyrimidinones.

Proteomics: A Promising Approach for Cancer Research Volume 2 Proteome signaling dysregulation in cancer, therapeutic interventions, and future perspectives provides an updated overview of scientific knowledge, achievements, and findings in the field of cancer proteomics. The field of cancer proteomics is very dynamic, with emerging trends specifically related to clinical solutions. The book content was developed to help readers get up to speed on the topic and easily apply learnings into research or clinical practice.Volume 2 covers proteome signaling, their dysregulation to therapeutics options and future prospects in 17 different signaling pathways. It capitalizes the enormous interest in proteomics among academics and gives new viewpoints on this topic in cancer treatment. It is a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of proteomics in cancer research and treatment.

Biological Insights of Multi-Omics Technologies in Human Diseases provides detailed information about the basics of multi-omic technologies, including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters, this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharmaceutical, socio-ethical, and economic perspectives.The chapters are designed in a well-defined chronology such that readers will intuitively understand the central idea. This book is an ideal resource for health professionals, scientists and researchers, nutritionists, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

With the emergence of new pesticide combinations and application methods, assessing their potential risks to non-target organisms and human well-being becomes paramount. Pesticide Toxicology and Risk Assessment focuses on the need and strategies for safe and efficient use of pesticides. It offers insights from toxicogenomics, enabling an understanding of the genetic and epigenetic factors influencing human susceptibility to chemical toxicity, thereby quantifying their impacts.This book underscores the significance of risk assessment methodologies considering real-time variables influencing pesticide exposure to the environment and humans. It provides comprehensive details about models designed to evaluate risks across a spectrum of scenarios, from worst-case to real-time situations, while outlining strategies to mitigate these risks proactively. Furthermore, this book delves into the critical need for conducting field studies, particularly in addressing innovative combinations and application techniques.

Key Features:

• Covers toxicogenomic insights, delving into genetic and epigenetic impacts on human susceptibility to chemical toxicity

• Provides insight into necessary field studies for new pesticide approaches

• Aids pesticide manufacturers with risk assessment and effective formulation insights

As an aid for regulatory bodies, the book facilitates the evaluation of risks linked to both established and innovative pesticides, promoting informed decisions on usage by integrating risk reduction approaches. Simultaneously, it serves as a valuable guide for pesticide manufacturers, offering insights into using risk assessment tools to develop secure and effective pesticide blends. This guidance expedites the introduction of novel pesticides that are efficient and safe for various applications.

With the emergence of new pesticide combinations and application methods, assessing their potential risks to non-target organisms and human well-being becomes paramount. Pesticide Toxicology and Risk Assessment focuses on the need and strategies for safe and efficient use of pesticides. It offers insights from toxicogenomics, enabling an understanding of the genetic and epigenetic factors influencing human susceptibility to chemical toxicity, thereby quantifying their impacts.This book underscores the significance of risk assessment methodologies considering real-time variables influencing pesticide exposure to the environment and humans. It provides comprehensive details about models designed to evaluate risks across a spectrum of scenarios, from worst-case to real-time situations, while outlining strategies to mitigate these risks proactively. Furthermore, this book delves into the critical need for conducting field studies, particularly in addressing innovative combinations and application techniques.

Key Features:

• Covers toxicogenomic insights, delving into genetic and epigenetic impacts on human susceptibility to chemical toxicity

• Provides insight into necessary field studies for new pesticide approaches

• Aids pesticide manufacturers with risk assessment and effective formulation insights

As an aid for regulatory bodies, the book facilitates the evaluation of risks linked to both established and innovative pesticides, promoting informed decisions on usage by integrating risk reduction approaches. Simultaneously, it serves as a valuable guide for pesticide manufacturers, offering insights into using risk assessment tools to develop secure and effective pesticide blends. This guidance expedites the introduction of novel pesticides that are efficient and safe for various applications.

Honey typically has a complex chemical and biochemical composition that invariably includes complex sugars, specific proteins, amino acids, phenols, vitamins, and rare minerals. It is reported to be beneficial in the treatment of various diseases, such as those affecting the respiratory, cardiovascular, gastrointestinal, and nervous systems, as well as diabetes mellitus and certain types of cancers; however, there is limited literature describing the use of honey in modern medicine.

This book provides evidence-based information on the pharmaceutical potential of honey along with its therapeutic applications and precise mechanisms of action. It discusses in detail the phytochemistry and pharmacological properties of honey, highlighting the economic and culturally significant medicinal uses of honey and comprehensively reviewing the scientific research on the traditional uses, chemical composition, scientific validation, and general pharmacognostical characteristics. Given its scope, it is a valuable tool for researchers and scientists interested in drug discovery and the chemistry and pharmacology of honey.