Abhishek Tiwari – författare

This unique volume covers specific aspects of the biological chemistry of terpenoids. It provides extensive information related to classification, general methods of extraction and isolation of terpenoids, synthesis and pharmacological activities of monoterpenoids, synthesis and medicinal uses of diterpenoids, biogenesis of terpenoids, synthesis and medicinal uses of sesqui terpenoids and sesterpenoids. Some terpenes are also classified as diterpene alkaloids. Most of the terpenoids with diverse molecular structures are biologically active and are used for the treatment of various diseases such as cancer, malaria, inflammation, tuberculosis and infection, and this is discussed.Features:Activities and biological relationships of terpenes An accurate assessment of where and what terpenes can lead to Discusses how microbes, in particular the actinomycetales, have well over 400 different gene clusters that produce terpenes Arranged by biological activities and usage Provides information on eukaryotic enzymes that have been shown to be a source of “ethnobotanical” terpenes

This unique volume covers specific aspects of the biological chemistry of terpenoids. It provides extensive information related to classification, general methods of extraction and isolation of terpenoids, synthesis and pharmacological activities of monoterpenoids, synthesis and medicinal uses of diterpenoids, biogenesis of terpenoids, synthesis and medicinal uses of sesqui terpenoids and sesterpenoids. Some terpenes are also classified as diterpene alkaloids. Most of the terpenoids with diverse molecular structures are biologically active and are used for the treatment of various diseases such as cancer, malaria, inflammation, tuberculosis and infection, and this is discussed.Features:Activities and biological relationships of terpenes An accurate assessment of where and what terpenes can lead to Discusses how microbes, in particular the actinomycetales, have well over 400 different gene clusters that produce terpenes Arranged by biological activities and usage Provides information on eukaryotic enzymes that have been shown to be a source of “ethnobotanical” terpenes

A comprehensive and authoritative exploration of Tempol (4-Hydroxy-TEMPO), an exceptional chemical compound with diverse applications in both scientific research and medical practice. This book delves into Tempol's unique properties, mechanisms of action, and its potential role in combating oxidative stress-related disorders. Includes a chapter devoted to the safe handling, storage, and disposal of Tempol in compliance with pharmaceutical regulations. The authors pay particular attention to pharmaceutical regulations in the industry.This book offers an in-depth exploration of Tempol (4-Hydroxy-TEMPO), covering its chemical, pharmaceutical, and medical applications, making it a valuable resource for researchers, academicians, and industry professionals.The chapters bridge chemistry, pharmacology, and medical sciences, detailing Tempol’s role in various fields such as terpenoid synthesis, cancer therapy, diabetic nephropathy, and ocular neuroprotection.The dedicated chapter emphasizes Tempol's safe handling, storage, and disposal, with a focus on adhering to pharmaceutical regulations, ensuring its practical utility for pharmaceutical and industrial applications.Mechanistic insights into Tempol's interaction with phenolic antioxidants and its role in oxidative stress inhibition provide theoretical depth, while discussions on industrial and therapeutic applications highlight its practical relevance.The inclusion of nano-formulation techniques for Tempol showcases cutting-edge approaches to enhance its bioavailability and efficacy, catering to the latest trends in drug delivery systems.

A comprehensive and authoritative exploration of Tempol (4-Hydroxy-TEMPO), an exceptional chemical compound with diverse applications in both scientific research and medical practice. This book delves into Tempol's unique properties, mechanisms of action, and its potential role in combating oxidative stress-related disorders. Includes a chapter devoted to the safe handling, storage, and disposal of Tempol in compliance with pharmaceutical regulations. The authors pay particular attention to pharmaceutical regulations in the industry.This book offers an in-depth exploration of Tempol (4-Hydroxy-TEMPO), covering its chemical, pharmaceutical, and medical applications, making it a valuable resource for researchers, academicians, and industry professionals.The chapters bridge chemistry, pharmacology, and medical sciences, detailing Tempol’s role in various fields such as terpenoid synthesis, cancer therapy, diabetic nephropathy, and ocular neuroprotection.The dedicated chapter emphasizes Tempol's safe handling, storage, and disposal, with a focus on adhering to pharmaceutical regulations, ensuring its practical utility for pharmaceutical and industrial applications.Mechanistic insights into Tempol's interaction with phenolic antioxidants and its role in oxidative stress inhibition provide theoretical depth, while discussions on industrial and therapeutic applications highlight its practical relevance.The inclusion of nano-formulation techniques for Tempol showcases cutting-edge approaches to enhance its bioavailability and efficacy, catering to the latest trends in drug delivery systems.

Exploring the Synthesis, Ethnopharmacology, and Therapeutic Applications of Bioactive Polyphenols offers a comprehensive examination of one of the most dynamic areas in natural product chemistry and drug discovery. Polyphenols, long recognized for their diverse biological activities, are now at the forefront of research in preventive medicine, nutraceuticals, and pharmaceutical innovation. This book brings together the chemistry, traditional uses, and modern therapeutic perspectives of bioactive polyphenols in a single, well-structured volume.The aim of this book is to bridge the gap between traditional ethnopharmacological knowledge and cutting-edge synthetic and therapeutic research. By integrating interdisciplinary perspectives, it provides a unique resource for understanding both the molecular intricacies of polyphenols and their real-world applications in treating chronic diseases. What sets this work apart is its balanced approach offering in-depth scientific analysis while also capturing the cultural and historical significance of these bioactive compounds.Key Features:Detailed coverage of the chemical synthesis and structural diversity of major polyphenols.Comprehensive insights into ethnopharmacological practices involving polyphenol-rich plants across different cultures.Thorough discussion of therapeutic applications, including cardiovascular, neuroprotective, anticancer, and anti-inflammatory potentials.Integration of recent advances in clinical studies and drug formulation strategies.This book includes extended chapters on nanotechnology-based delivery systems and sustainability in polyphenol extraction, and updated case studies highlighting translational research.This volume is an essential reference for researchers, academicians, and graduate students in pharmaceutical sciences, medicinal chemistry, pharmacognosy, and natural product research. It will also be invaluable to health-care professionals, nutritionists, and industry specialists seeking to explore the therapeutic promise of polyphenols and their role in future drug discovery.

Studies reveal that lung cancer causes about 22% of all cancer deaths worldwide, posing a significant challenge to the healthcare system. This new book, The Role of Nanotechnology in Holistic Lung Cancer Management and Treatment, is a comprehensive exploration of cutting-edge strategies in combating lung cancer and minimizing its harm.Covering a wide array of topics that range from the molecular mechanisms underlying lung cancer to the latest advancements in nanotechnology-based therapies, the book offers valuable insights into different aspects of lung cancer management, including the roles of dendrimers, polymeric micelles, nano-emulsions, inhalation delivery systems, novel nano-imaging platforms, hydrogels, quantum dots, and nanotherapeutics. It also covers drug delivery systems such as inhalation drug delivery systems, polymeric nanoparticle-based drug/gene delivery, SLN-based gene delivery, and liposome-based drug delivery for lung cancer. This book also addresses the impact of carcinogenic pollutants on lung cancer development, highlighting the importance of understanding environmental factors and implementing intervention strategies. Additionally, it delves into ongoing research and clinical trials, shedding light on promising nanotechnological approaches for more effective lung cancer treatment.The book will provide helpful insight on role of nanotechnology in holistic lung cancer for medical researchers, medical professionals, educators, and policymakers involved in fields related to nanotechnology and oncology.

Lung cancer remains one of the most prevalent and challenging malignancies, contributing significantly to global cancer-related morbidity and mortality. This new book explores various facets of lung cancer, providing an extensive overview of its molecular underpinnings, diagnostic modalities, treatment strategies, and the burgeoning field of nanotechnology in cancer therapeutics. It first provides an insightful overview of lung cancer, shedding light on its pervasiveness, etiological underpinnings, and the diverse therapeutic modalities employed in tackling both non-small cell lung cancer and small cell lung cancer. The book then goes on to cover the pathogenesis and molecular biology of lung cancer. Also discussed are diagnostic imaging techniques that explain lung cancer staging and characterization. The book also explores the development of targeted drug delivery systems, illuminating the evolving landscape of targeted therapies and the persistent challenges posed by therapeutic resistance and the role of diverse polymeric and lipid-based nanoparticle formulations as powerful tools in drug and gene delivery, offering tailored solutions to the multifaceted challenges of lung cancer treatment.

Herbal drugs have been used in healthcare for thousands of years. Recently, herbal drugs are experiencing a resurgence in popularity due to their perceived safety, efficacy, and potential health benefits. This new book explores many aspects in the herbal drug sector, addressing quality control, formulation development, manufacturing, regulatory aspects, and the role of herbal drug in global healthcare management.The book introduces herbal drugs, their historical developments and cultural significance. It also covers the challenges of modernizing herbal formulations and the designs and layouts for herbal drug production facilities. It also underscores the need for testing, quality control, regulatory compliance and sustainable sourcing practices, discussing quality standards and testing of natural products. The book covers patent and intellectual property rights within the herbal industry and details the frameworks governing herbal products globally and the issues related to herbal drug licensing. The book finally looks at future and emerging trends of the herbal industry.

Globalization, Urbanization, and Sustainability: What Can We Do? provides students with an introduction to the multifaceted nature of civilization and its impact on our environment. The text explores the intricate interplay between globalization, urbanization, and sustainability, and examines the environmental and health impacts of modern society, including climate change, resource consumption, and waste.The book's nine chapters focus on a distinct aspect of globalization, urbanization, and sustainability, including historical perspectives on urbanism and trade, economic fundamentals of global capitalism, world financial and trade institutions, demography, poverty and economic development, public health, and steps individuals can take to preserve our world and act as good stewards of the earth.Designed to foster a critical awareness of the costs associated with modern systems of production and inspire sustainable solutions, Globalization, Urbanization, and Sustainability is an exceptional resource for courses and programs in environmental studies, urban planning, international studies, economics, public health and sustainability.

This new book, Essentials of Herbal Drugs, is a comprehensive guide to understanding the fundamental aspects of herbal drugs and their significance in modern healthcare, offering a valuable resource on the rich history, quality control measures, cultivation practices, metabolic pathways, extraction techniques, regulatory considerations, and future trends of herbal medicines.The book details the role of traditional healing practices since time immemorial, discussing the diverse forms and therapeutic benefits of herbs. Important topics on the use of herbal drugs in modern times are also discussed, including quality control of herbal drugs and standardization, proper methods of cultivation, extraction and assessment, isolation, identification and analysis of phytoconstituents, and understanding the metabolic pathways of plants.The book also looks at nutraceuticals and their regulatory requirements and challenges. It also observes the biological screening, toxicity testing, and regulations of herbal drugs. Future prospects of herbal drugs including pharmacovigilance of natural products, and phyto-pharmaceutical research, highlighting emerging opportunities for drug discovery and the potential of natural compounds in healthcare.Essentials of Herbal Medicine will serve as a comprehensive resource for students, researchers, and practitioners interested in herbal drugs and their therapeutic applications.

This book presents peer reviewed articles from the International Conference on Fundamental and Industrial Research on Materials- iConFIRM 2023; held from 11th to 14th Dec at Ropar in India. It includes recent advances in the area of mechanics of metallic, nano and energy materials, extractive metallurgy, and processing. Fundamental research works including development and characterization of new alloys, ceramics, composites and nano materials along with advanced characterization techniques such as XRD, SEM and TEM and mathematical modelling, finite element simulations, molecular dynamics, machine learning and similar other advanced numerical, theoretical and experimental techniques in the field of materials and metallurgy.

This book presents peer reviewed articles from the International Conference on Fundamental and Industrial Research on Materials- iConFIRM 2023; held from 11th to 14th Dec at Ropar in India. It includes recent advances in the area of mechanics of metallic, nano and energy materials, extractive metallurgy, and processing. Fundamental research works including development and characterization of new alloys, ceramics, composites and nano materials along with advanced characterization techniques such as XRD, SEM and TEM and mathematical modelling, finite element simulations, molecular dynamics, machine learning and similar other advanced numerical, theoretical and experimental techniques in the field of materials and metallurgy.