Bimal Krishna Banik - Böcker

Natural Products as Anticancer Agents introduces the different types of natural products that have been used for cancer treatment. Divided into four parts, covering anticancer agents derived from terrestrial plants, anticancer agents derived from the marine environment, and anticancer agents derived from microorganisms, as well as evaluation of new anticancer agents, each part includes discussion of the properties, synthesis/extraction, storage, mechanism of action, and usage of the molecules. Discussion of the future prospects in anticancer natural products-including several new trends and an indication of where research in this area is likely to go in the future-is also included. Assists in the identification of risk factors associated with the drug development process Includes process diagrams detailing the procedure for the isolation and purification of molecules Covers cost-effective green approaches in the development of anticancer drugs

Due to their medicinal activity and potential use as synthetic starting materials, studies on beta-lactams have increased significantly. This unique volume takes readers on a tour de force from the concept of antibiosis to the serendipity of antibiotics, evolution of beta‐lactam development, and molecular biology of antibiotic resistance. These areas of research have culminated in a deeper understanding of microbiology, particularly in the area of bacterial cell wall synthesis and recycling. Considerable work has been performed by chemists and biologists to continue updating their findings about beta-lactam synthesis.Features:Stereoselective synthesis of monocyclic, bicyclic, and polycyclic beta-lactamsMicrowave, ultrasound, and solid support-mediated preparation of beta-lactamsDiverse medicinal activities including anticancer activities of beta-lactams and products obtained from themNanoparticles, artificial intelligence, and dipole moments in beta-lactam scienceSynthesis and mechanism of formation of polyaromatic beta-lactams

This unique volume covers specific aspects of the biological chemistry of terpenoids. It provides extensive information related to classification, general methods of extraction and isolation of terpenoids, synthesis and pharmacological activities of monoterpenoids, synthesis and medicinal uses of diterpenoids, biogenesis of terpenoids, synthesis and medicinal uses of sesqui terpenoids and sesterpenoids. Some terpenes are also classified as diterpene alkaloids. Most of the terpenoids with diverse molecular structures are biologically active and are used for the treatment of various diseases such as cancer, malaria, inflammation, tuberculosis and infection, and this is discussed.Features:Activities and biological relationships of terpenes An accurate assessment of where and what terpenes can lead to Discusses how microbes, in particular the actinomycetales, have well over 400 different gene clusters that produce terpenes Arranged by biological activities and usage Provides information on eukaryotic enzymes that have been shown to be a source of “ethnobotanical” terpenes

Comprehensive Guide to Green Chemistry: Principles, Materials, and Applications provides an authoritative analysis of green and sustainable chemistry, integrating foundational principles with the advanced materials and technologies that are transforming research and industrial applications. The book provides detailed exploration of green solvents, bio-based polymers, nanomaterials, photocatalysis, and advanced oxidation processes, highlighting their roles in minimizing environmental impact. The text further addresses sustainable synthetic methodologies, pollution control technologies for water, air, and soil, and waste-to-energy strategies within circular economy models, providing a holistic view of resource-efficient chemical practices.It equips professionals and academics with the knowledge and tools necessary to implement environmentally responsible strategies that advance sustainable development objectives. This essential reference supports the transition toward eco-efficient chemistry, enabling the reduction of pollution, conservation of resources, and promotion of long-term ecological balance across diverse sectors.Provides a comprehensive and structured reference for green and sustainable chemistry, meeting the informational needs of both academia and industry professionalsHighlights real-world applications and emerging technologies such as AI, nanomaterials, and green synthesis, positioning the book as a forward-looking resource to support innovation and sustainabilityFeatures visual elements like flow diagrams, process charts, and comparative tables that enhance understanding and facilitate quick reference

This unique volume covers specific aspects of the biological chemistry of terpenoids. It provides extensive information related to classification, general methods of extraction and isolation of terpenoids, synthesis and pharmacological activities of monoterpenoids, synthesis and medicinal uses of diterpenoids, biogenesis of terpenoids, synthesis and medicinal uses of sesqui terpenoids and sesterpenoids. Some terpenes are also classified as diterpene alkaloids. Most of the terpenoids with diverse molecular structures are biologically active and are used for the treatment of various diseases such as cancer, malaria, inflammation, tuberculosis and infection, and this is discussed.Features:Activities and biological relationships of terpenes An accurate assessment of where and what terpenes can lead to Discusses how microbes, in particular the actinomycetales, have well over 400 different gene clusters that produce terpenes Arranged by biological activities and usage Provides information on eukaryotic enzymes that have been shown to be a source of “ethnobotanical” terpenes

Trace elements selenium, vanadium and chromium play an essential role in the nutrition of both animals and humans. Their accumulation in various environments and the subsequent transition of these elements into the food chain significantly affect human and environmental health. This volume emphasizes the integrative aspects of selenium, vanadium and chromium with chapters dedicated to their fundamental chemistry, biochemistry, clinical science and environmental effects. Each chapter focuses on the advancement of scientific knowledge about these trace elements. Important studies on these elements will be described through interdisciplinary approaches.Emphasizes chemistry, biology, and toxicology of trace elements Se, V & Cr helping readers to understand their cycle in environment and effects on humans.Focuses on three important trace minerals and their recent research involving improvement of human health.Timely presentation of research being conducted on the roles of Se, V, Cr in health and disease.Addresses usefulness of trace metals in food science & nutrition, unlike other books.Distinctively presents extensive and integrative information of the fundamental aspects of Selenium, Vanadium, and Chromium in an easy to read format.

A comprehensive and authoritative exploration of Tempol (4-Hydroxy-TEMPO), an exceptional chemical compound with diverse applications in both scientific research and medical practice. This book delves into Tempol's unique properties, mechanisms of action, and its potential role in combating oxidative stress-related disorders. Includes a chapter devoted to the safe handling, storage, and disposal of Tempol in compliance with pharmaceutical regulations. The authors pay particular attention to pharmaceutical regulations in the industry.This book offers an in-depth exploration of Tempol (4-Hydroxy-TEMPO), covering its chemical, pharmaceutical, and medical applications, making it a valuable resource for researchers, academicians, and industry professionals.The chapters bridge chemistry, pharmacology, and medical sciences, detailing Tempol’s role in various fields such as terpenoid synthesis, cancer therapy, diabetic nephropathy, and ocular neuroprotection.The dedicated chapter emphasizes Tempol's safe handling, storage, and disposal, with a focus on adhering to pharmaceutical regulations, ensuring its practical utility for pharmaceutical and industrial applications.Mechanistic insights into Tempol's interaction with phenolic antioxidants and its role in oxidative stress inhibition provide theoretical depth, while discussions on industrial and therapeutic applications highlight its practical relevance.The inclusion of nano-formulation techniques for Tempol showcases cutting-edge approaches to enhance its bioavailability and efficacy, catering to the latest trends in drug delivery systems.

A comprehensive and authoritative exploration of Tempol (4-Hydroxy-TEMPO), an exceptional chemical compound with diverse applications in both scientific research and medical practice. This book delves into Tempol's unique properties, mechanisms of action, and its potential role in combating oxidative stress-related disorders. Includes a chapter devoted to the safe handling, storage, and disposal of Tempol in compliance with pharmaceutical regulations. The authors pay particular attention to pharmaceutical regulations in the industry.This book offers an in-depth exploration of Tempol (4-Hydroxy-TEMPO), covering its chemical, pharmaceutical, and medical applications, making it a valuable resource for researchers, academicians, and industry professionals.The chapters bridge chemistry, pharmacology, and medical sciences, detailing Tempol’s role in various fields such as terpenoid synthesis, cancer therapy, diabetic nephropathy, and ocular neuroprotection.The dedicated chapter emphasizes Tempol's safe handling, storage, and disposal, with a focus on adhering to pharmaceutical regulations, ensuring its practical utility for pharmaceutical and industrial applications.Mechanistic insights into Tempol's interaction with phenolic antioxidants and its role in oxidative stress inhibition provide theoretical depth, while discussions on industrial and therapeutic applications highlight its practical relevance.The inclusion of nano-formulation techniques for Tempol showcases cutting-edge approaches to enhance its bioavailability and efficacy, catering to the latest trends in drug delivery systems.

The exceptional capability of N-heterocyclic scaffolds to function as biomimetics and active pharmacophores has resulted in modulating their structure, reactivity and formulation for effective drugs. The direct and viable synthetic strategies of these molecules are valuable features. Numerous methods revealed the general synthesis and application of N-heterocyclic compounds through conventional as well as modified approaches. Additionally, the advent of combinatorial and medicinal chemistry for the synthesis of new heterocyclic compounds for drug discovery have added a new essence to existing protocol.Key FeaturesBridges the gap by integrating both chemical and biological aspects of heterocycles in a cohesive and comprehensive manner.Serves as a valuable resource for researchers, students, and professionals who need focused insights into heterocyclic chemistry and its applications in biology.Offers new perspectives on how these compounds influence or can be influenced by biological systems, and how they may be utilized in fields of drug design and development.Illustrates the importance of the ring size of heterocyclic compounds and heteroatoms involved with its biological applications.The biological evaluation and significance of various chiral and achiral heterocycles along with chemical strategies will attract the scientific community.

Nanotechnology has been recognized for its transformative potential across various industries for decades, sparking widespread interest among researchers and innovators seeking to explores its capabilities for sustainable solutions. It remains one of the most dynamic and extensively studied fields in modern science. Nanotechnology involves the manipulation of matter at the nanoscale, where unique properties of materials emerge due to their size and structure. These nanomaterials play a pivotal role in advancing applications in energy, healthcare, environmental remediation and sustainable economic development. In recent years, green nanotechnology, particularly the eco-friendly synthesis of nanomaterials, has gained significant attention for its ability to minimize environmental impact while maximizing efficiency. Nanomaterials exhibit remarkable properties such as enhanced strength, conductivity and reactivity that make them indispensable in addressing global challenges like climate change, water scarcity and healthcare innovation, positioning nanotechnology as a cornerstone of sustainable progress.The book delves into the structural and functional properties of nanomaterials, which are critical for their applications in clean energy production, environmental remediation, water treatment and healthcare. It highlights their environmental significance, including their use in mitigating climate change, enhancing construction materials, and developing fire-retardant solutions. The fundamentals of nanotechnology are thoroughly explored, alongside cutting-edge developments in synthesis, characterization methods, and applications, covering chemical, optical, thermal, and structural properties. Additionally, the book addresses the environmental fate, health hazards, and regulatory frameworks of nanomaterials, offering a balanced perspective on their deployment. With contributions from leading experts, this book serves as an authoritative resource for researchers, policymakers, and industry professionals to drive sustainable economic growth while addressing pressing global challenges.Key Features:Comprehensive Coverage: The book spans a wide range of nanotechnology applications, from energy production and storage to healthcare, environmental remediation and sustainable economic development.Multidisciplinary Approach: Contributions from various experts provide insights into nanotechnology's role in diverse fields, including construction, fire retardancy and climate change mitigation.Focus on Sustainability: Emphasis on eco-friendly and green nanotechnology solutions, such as green synthesis of nanomaterials and sustainable development goals (SDGs).Environmental and Health Perspectives: Detailed exploration of nanomaterials' environmental fate, transport, and health hazards alongside their role in environmental remediation and water treatment.Policy and Regulation Insights: Discussion on policy and regulatory frameworks to support a green economy through nanotechnology.Future-Oriented Outlook: Analysis of current trends and future prospects, particularly in healthcare, clean energy and sustainable economic development.Expert Contributions: Chapters authored by specialists in their respective fields, ensuring authoritative and in-depth content.Lifecycle Thinking: Inclusion of lifecycle perspectives to assess the long-term impacts and sustainability of nanotechnology applications.

Nanotechnology has been recognized for its transformative potential across various industries for decades, sparking widespread interest among researchers and innovators seeking to explores its capabilities for sustainable solutions. It remains one of the most dynamic and extensively studied fields in modern science. Nanotechnology involves the manipulation of matter at the nanoscale, where unique properties of materials emerge due to their size and structure. These nanomaterials play a pivotal role in advancing applications in energy, healthcare, environmental remediation and sustainable economic development. In recent years, green nanotechnology, particularly the eco-friendly synthesis of nanomaterials, has gained significant attention for its ability to minimize environmental impact while maximizing efficiency. Nanomaterials exhibit remarkable properties such as enhanced strength, conductivity and reactivity that make them indispensable in addressing global challenges like climate change, water scarcity and healthcare innovation, positioning nanotechnology as a cornerstone of sustainable progress.The book delves into the structural and functional properties of nanomaterials, which are critical for their applications in clean energy production, environmental remediation, water treatment and healthcare. It highlights their environmental significance, including their use in mitigating climate change, enhancing construction materials, and developing fire-retardant solutions. The fundamentals of nanotechnology are thoroughly explored, alongside cutting-edge developments in synthesis, characterization methods, and applications, covering chemical, optical, thermal, and structural properties. Additionally, the book addresses the environmental fate, health hazards, and regulatory frameworks of nanomaterials, offering a balanced perspective on their deployment. With contributions from leading experts, this book serves as an authoritative resource for researchers, policymakers, and industry professionals to drive sustainable economic growth while addressing pressing global challenges.Key Features:Comprehensive Coverage: The book spans a wide range of nanotechnology applications, from energy production and storage to healthcare, environmental remediation and sustainable economic development.Multidisciplinary Approach: Contributions from various experts provide insights into nanotechnology's role in diverse fields, including construction, fire retardancy and climate change mitigation.Focus on Sustainability: Emphasis on eco-friendly and green nanotechnology solutions, such as green synthesis of nanomaterials and sustainable development goals (SDGs).Environmental and Health Perspectives: Detailed exploration of nanomaterials' environmental fate, transport, and health hazards alongside their role in environmental remediation and water treatment.Policy and Regulation Insights: Discussion on policy and regulatory frameworks to support a green economy through nanotechnology.Future-Oriented Outlook: Analysis of current trends and future prospects, particularly in healthcare, clean energy and sustainable economic development.Expert Contributions: Chapters authored by specialists in their respective fields, ensuring authoritative and in-depth content.Lifecycle Thinking: Inclusion of lifecycle perspectives to assess the long-term impacts and sustainability of nanotechnology applications.

This book deals with chemical reactions which are triggered when light energy is absorbed by a substance’s molecules. It highlights the synthesis, molecular mechanism, chemical and biological properties of organic compounds and also focuses on recent advances in drug development related to cancer and other ailments. It will be helpful for researchers during target identification, lead identification, and optimization during the drug development process as well as in designing new molecules based on the data retrieved from the literature survey.Features: • Methods for creating carbon-carbon and carbon-heteroatom bonds following green chemistry and concepts on electron-donor-acceptor pathways.• Focuses on medicinally important molecules, in particular against diverse cancers.• Describes synthesis of natural products.• Describe economical and practical pathways.• Encourages new ways to conduct research in organic and medicinal chemistry.This book will be beneficial to undergraduates, postgraduates, research scholars, and young teachers in chemistry and biological science, pharmacists, pharmacologists, clinicians, industrialists, and biochemists.

Kinase inhibitors are the type of medications that target enzymes called kinases, which play a crucial role in signaling pathways involved in cell growth, proliferation, and survival. These inhibitors are used in the treatment of various cancers and other diseases. This book provides essential information in the design of new drug molecules for the development of kinase inhibitors. It includes the existing drugs and those under clinical trial that are involved in the development process.Key FeaturesHighlights the synthesis, molecular mechanism, biochemical pathways, chemical and biological properties of kinase inhibitors.Focuses on recent advances in these drugs used in the field of cancer and other diseases.Researchers are provided with information on target identification, lead identification, and optimization during the drug development process.

Heterocyclic systems are defined by the integration of one or more heteroatoms within a cyclic framework and serve as the structural foundation for a vast array of natural products, clinical pharmaceuticals, and advanced functional materials. This work examines the synthetic landscape of heterocycles, prioritizing the development of robust methodologies, mechanistic insights, and late-stage modifications. Given their pervasive role in modulating anticancer, antimicrobial, and anti-inflammatory and many other pathways, these scaffolds remain central to medicinal chemistry. By elucidating the intricate interplay between chemical architecture and pharmacological efficacy, this study promotes the thought process to the rational design of next-generation therapeutic agents.Key FeaturesBridges the gap by integrating both chemical and biological aspects of heterocycles in a cohesive and comprehensive manner.Serves as a valuable resource for researchers, students, and professionals who need focused insights into heterocyclic chemistry and its applications in biology.Offers new perspectives on how these compounds influence or can be influenced by biological systems, and how they may be utilized in fields of drug design and development.Illustrates the importance of the ring size of heterocyclic compounds and heteroatoms involved with its biological applications.The biological evaluation and significance of various chiral and achiral heterocycles along with chemical strategies will attract the scientific community.

Organocatalysis are an important tool for greener catalytic processes due to the lack of precious metals used. This book explores different organocatalysts and their use in synthesis. Topics covered include zwitterionic imidazolium salt catalysts, asymmetric catalysts in aqueous media, beaker yeast catalysis, organocatalysts for Aldol and Michael reactions, amino acid-based organocatalysts, and Brönsted acidic surfactant organocatalysts.

Cancer is an incredibly diverse and difficult disease to treat, and even after decades of research there is no definitive cure. Therefore, it is highly crucial to search for novel and new organic molecules with high potency, low toxicity, and low mutagenicity with selective anticancer properties that are able to overcome frequently developed resistance to available drugs. Heterocyclic anticancer agents are an important class of drugs for cancer therapies. This book explores different heterocycles and their use as anticancer therapies. Topics covered include different heterocyclic derivatives, the impact of heterocycles on anticancer agent development, and naturally occurring heterocycles.