Alfred E. Chang – författare

This issue of Surgical Oncology Clinics of North America focuses on Immunotherapy for Solid Malignancies and is edited by Dr. Alfred E. Chang. Articles will include: Current immunotherapy practices for melanoma; Immunotherapy for ovarian cancer; Vaccines therapies for melanoma; Vaccine therapies for breast cancer; Induced pleuripotent T cells for adoptive immunotherapy; Future research goals in immunotherapy; Oncolytic immunotherapy; Adoptive T cell therapy for solid malignancies; Checkpoint inhibition immunotherapy; Toxicities of immunotherapy agents; Immunologic targeting of cancer stem cells; Role of surgery in combination with immunotherapy; and more!

Oncology: An Evidence-Based Approach is a textbook designed to reflect the principles and current practice of oncology with contributors from the fields of medical, surgical, and radiation oncology. The textbook will incorporate an evidence-based approach, enabling the reader to make decisions on the basis of concrete data. Sections on solid tumors, hematologic malignancies and the practice of oncology address the natural history and therapy for the full spectrum of neoplastic diseases in the adult. Further sections present fundamentals of supportive care of the cancer patient, the management of oncologic emergencies and acute toxicities of therapy, as well as care of metastatic disease and the terminally-ill patient. Breaking new ground, the textbook features thoughtful, in-depth sections on cancer prevention and control, cancer surviorship, the economics of cancer care, and cancer informatics. Cancer imaging is covered with an organ system-based approach, with an additional chapter on the especially intriguing potential of PET.Furthermore, a comprehensive section on translational basic science reviews the fundamentals of molecular biology, the cell cycle and signal transduction, carcinogenesis, cancer genetics, the biology of invations and metastasis, and tumor immunology.

"…the ambitious undertaking of creating an evidence-based textbook of surgery has largely succeeded and I heartily recommend it. Surgery: Basic Science and Clinical Evidence have something for everyone, from the newest surgical resident to the established surgeon in practice." JAMA on the First Edition"During a period of numerous adventures in the textbook arena, this is different in focus and quality…reader friendly with excellent illustrations and 200 evidence-based tables" Archives of Surgery on the First Edition"The text is clearly written, and the chapters are well illustrated...Chief residents in surgery preparing for their board examinations will find this book especially helpful, because the chapters deal in a comprehensive way with the nine major areas of general surgery identified by the American Board of Surgery." New England Journal of Medicine on the First Edition"…a strong text for the general surgeon, regardless of training status, academic affiliation, or practice venue. There is much here for everyone. The work is current, fairly complete, objective, and very readable compared with other general surgical textbooks." Surgical Infections on the First Edition. The second edition of Surgery: Basic Science and Clinical Evidence features fully revised and updated information on the evidence-based practice of surgery, significant new sections on trauma and critical care on the often challenging surgical care of unique populations; (elderly, pediatric, immunocompromised, and obese patients). The internationally recognized editors and authors have maintained their evidence-based approach throughout the text with thoughtful and timely new chapters on the pre- and post-operative care of the cardiac surgery patient, intestinal transplantation, surgical infections, the fundamentals of cancer genetics and proteomics, and discussions of electrosurgical instruments, robotics, imaging modalities, and other emerging technologies influencing the modern practice of surgery. The oft-cited chapter on the principles of evidence-based decision-making in surgical practice is completely updated for the second edition, presenting the reader with a framework for the evidence-based practice of surgery. The First Edition’s strong emphasis on the basic science underlying the practice of surgery is upheld, providing readers with solid preparation for inservice and recertification examinations. Clinically focused sections in gastrointestinal, vascular, cardiothoracic, transplant, and cancer surgery enable the surgeon to make decisions based upon the most relevant data. The text is enhanced by more than 1,000 illustrations and hundreds of the signature evidence-based tables that made the first edition of SURGERY an instant classic. With is strong basic science coverage and emphasis on evidence-based decision making, the Second Edition is required reading for all general surgery trainees, practitioners, and surgical subspecialists.