Ashutosh Mani – författare

Plants are an indispensable part of human and animal lives for nutrition and health. But pests, diseases and abiotic stress adversely affect crop yield, which ultimately places significant pressure on society to provide food to an increasing population. Moreover, it also encourages increased chemical/pesticide usage on crops, which we see in the biomagnification of toxic and hazardous compounds polluting water bodies, soil and the environment. This condition will continue to worsen in the future due to the resistance-acquiring ability of pathogens against plant defense and chemical treatments. In addition, environmental disturbances and consumer health issues are being reported more promptly than before due to intensive use of pesticides in food production. Plant diseases affect our daily lives, as the use of insecticides and pesticides has become part of our food chain. As a result, precise disease diagnosis and management is crucial in order to avoid huge losses in plant production and related commodities. Accurate detection, precise diagnosis and proper management can play a significant role in keeping plants free from pathogens. In this book, scientists, researchers and scholars share their research knowledge, offering a valuable resource for understanding plant diseases, pathogen interaction and responses to stress through an omics perspective, contributing to further advancements in the fieldDiseases in plants may be caused by various factors, such as viruses, bacteria, fungi and abiotic stress. Disease causes low crop yield, production of poor-quality fruits and grains, and deficiency of nutrients, which have a direct impact on human and animal health. A genomics-based approach can be applied to disease diagnosis; disease outbreak; evolution of plant and pathogen genome for disease outbreak in relation to climate change; and development of long-term strategies for plant health and defense. This book presents an overview of omics technologies and approaches used to understand:the relation between plants and their environment in terms of diseasesresponses to abiotic stressthe genomics of plant–pathogen interactionherbicide-resistance mechanismsthe epigenetics of plant–pathogen interactiongene regulation during abiotic stress responsethe oxidative stress response

Plants are an indispensable part of human and animal lives for nutrition and health. But pests, diseases and abiotic stress adversely affect crop yield, which ultimately places significant pressure on society to provide food to an increasing population. Moreover, it also encourages increased chemical/pesticide usage on crops, which we see in the biomagnification of toxic and hazardous compounds polluting water bodies, soil and the environment. This condition will continue to worsen in the future due to the resistance-acquiring ability of pathogens against plant defense and chemical treatments. In addition, environmental disturbances and consumer health issues are being reported more promptly than before due to intensive use of pesticides in food production. Plant diseases affect our daily lives, as the use of insecticides and pesticides has become part of our food chain. As a result, precise disease diagnosis and management is crucial in order to avoid huge losses in plant production and related commodities. Accurate detection, precise diagnosis and proper management can play a significant role in keeping plants free from pathogens. In this book, scientists, researchers and scholars share their research knowledge, offering a valuable resource for understanding plant diseases, pathogen interaction and responses to stress through an omics perspective, contributing to further advancements in the field

Diseases in plants may be caused by various factors, such as viruses, bacteria, fungi and abiotic stress. Disease causes low crop yield, production of poor-quality fruits and grains, and deficiency of nutrients, which have a direct impact on human and animal health. A genomics-based approach can be applied to disease diagnosis; disease outbreak; evolution of plant and pathogen genome for disease outbreak in relation to climate change; and development of long-term strategies for plant health and defense. This book presents an overview of omics technologies and approaches used to understand:

the relation between plants and their environment in terms of diseases responses to abiotic stress the genomics of plant–pathogen interaction herbicide-resistance mechanisms the epigenetics of plant–pathogen interaction gene regulation during abiotic stress response the oxidative stress response

Plants are an indispensable part of human and animal lives for nutrition and health. But pests, diseases and abiotic stress adversely affect crop yield, which ultimately places significant pressure on society to provide food to an increasing population. Moreover, it also encourages increased chemical/pesticide usage on crops, which we see in the biomagnification of toxic and hazardous compounds polluting water bodies, soil and the environment. This condition will continue to worsen in the future due to the resistance-acquiring ability of pathogens against plant defense and chemical treatments. In addition, environmental disturbances and consumer health issues are being reported more promptly than before due to intensive use of pesticides in food production. Plant diseases affect our daily lives, as the use of insecticides and pesticides has become part of our food chain. As a result, precise disease diagnosis and management is crucial in order to avoid huge losses in plant production and related commodities. Accurate detection, precise diagnosis and proper management can play a significant role in keeping plants free from pathogens. In this book, scientists, researchers and scholars share their research knowledge, offering a valuable resource for understanding plant diseases, pathogen interaction and responses to stress through an omics perspective, contributing to further advancements in the field

Diseases in plants may be caused by various factors, such as viruses, bacteria, fungi and abiotic stress. Disease causes low crop yield, production of poor-quality fruits and grains, and deficiency of nutrients, which have a direct impact on human and animal health. A genomics-based approach can be applied to disease diagnosis; disease outbreak; evolution of plant and pathogen genome for disease outbreak in relation to climate change; and development of long-term strategies for plant health and defense. This book presents an overview of omics technologies and approaches used to understand:

the relation between plants and their environment in terms of diseases responses to abiotic stress the genomics of plant–pathogen interaction herbicide-resistance mechanisms the epigenetics of plant–pathogen interaction gene regulation during abiotic stress response the oxidative stress response

This book, Pharmacology of Plants and Plant Derived Biologically Active Molecules, delves into the interesting world of phytochemicals and their therapeutic applications. It explores the journey from traditional medicine practices such as Ayurveda to modern scientific understanding, providing a comprehensive analysis of the chemistry, pharmacology, and therapeutic potential of plant-derived compounds. The detailed discussions on recent advancements and future directions in the field of pharmacology of plants, including novel extraction techniques, structure-activity relationship studies, and cutting-edge applications in various diseases, are the unique selling point (USP) of this book, setting it apart from the available books. Furthermore, it explores the exciting frontiers of anticancerous and antidiabetic molecules derived from plants.Key Features:Focus on advancements in extraction techniques for phytochemicals.Recent advances in understanding the pharmacological effects of primary and secondary metabolitesAnalysis of structure-activity relationships of biomoleculesFuture directions for integrating natural therapies into modern medicineRole of plants in homeopathic and Ayurvedic treatmentsApplication of computational and AI techniques in phytochemistryComprehensive review of anticancer biomolecules in the Simaroubaceae familyImportance of dose-dependent studies for medicinal extractsExploration of herbal remedies for ulcers and ocular diseasesThis book offers a comprehensive and insightful perspective on the therapeutic potential of plant-derived molecules and serves as an invaluable resource for researchers, students, and healthcare professionals interested in the pharmacology of plants and the development of novel therapeutics from natural sources.

This book explores the therapeutic potential of everyday kitchen ingredients, blending traditional practices with modern scientific analysis. It provides insights beyond the regular culinary use of vegetables and spices, and presents a comprehensive analysis of their chemistry, nutraceutical roles, and pharmacological applications. The diverse range of topics will offer readers a glimpse into the profound medicinal benefits these ingredients hold.With contributions from leading researchers at eminent institutions, the book encompasses the therapeutic potential of daily-use kitchen ingredients, their importance in historical and cultural contexts, and their relevance in modern medicine. This volume will help to reveal the true power of kitchen ingredients through scientific evidence.Key features include:A diverse range of topics on the therapeutic roles and nutraceutical significance of vegetables such as garlic, spinach, capsicum, fennels, onion, leafy vegetables, and others.A comprehensive insight into the phytochemistry and pharmacology of spices such as clove, cinnamon, ginger, cumin, cardamom, nutmeg, asafoetida, thyme, and more.The utilization of different kitchen ingredients for nutraceutical purposes in addressing chronic illnesses such as cancer and diabetes.Insight into the pharmacological role of essential oils derived from spices.Comprehensive insights into allergenicity, toxicity profiles, and dose-dependent studies.A detailed discussion on clinical evidence of assessments done on functional spices.This book is an essential resource for students, researchers, faculties, and healthcare professionals working in naturopathy. Exploration of the Medicinal Potential of Kitchen Ingredients promises to inspire innovative solutions and expand horizons in the fields of pharmacology and natural therapeutics.

Plant-Associated Medicinal Nano-Chemistry is a collection of 15 meticulously curated chapters that interconnects the transformative synergy between plant-derived bioactives and advanced nanotechnological platforms. This book reveals the pathways of green nanoparticle synthesis from plant sources, charting a dense trajectory through their complex applications—from targeted drug release and biosensing to innovative food preservation methods. A necessity for nanomedicine and pharmacognosy visionaries, and environmentally aware chemists, this handbook blends innovation and sustainability.Salient features:The book delivers holistic and in-depth coverage of plant-mediated nanoparticle synthesis with detailed descriptions of biomedical, therapeutic, and diagnostic applicationsInterdisciplinary integration of various themes related to nanotech, phytochemistry, molecular biology, toxicology, biosensing, food science, and regulatory affairs offers a truly rational approachInclusion of topics such as nanocellulose production, noscapine-potentiated cancer therapies, and real-time detection of molecular hazards highlights the pioneering innovations in the field of drug developmentEach chapter reflects the latest experimental findings and theoretical frameworks enriched by the insights of domain experts and promises to deliver scholar-driven excellenceChapters on eco-friendly synthesis routes, emphasizing biodegradable technologies, minimal environmental impact, and ethical standards in nano-biomedicine, support the idea of sustainability

This book, Pharmacology of Plants and Plant Derived Biologically Active Molecules, delves into the interesting world of phytochemicals and their therapeutic applications. It explores the journey from traditional medicine practices such as Ayurveda to modern scientific understanding, providing a comprehensive analysis of the chemistry, pharmacology, and therapeutic potential of plant-derived compounds. The detailed discussions on recent advancements and future directions in the field of pharmacology of plants, including novel extraction techniques, structure-activity relationship studies, and cutting-edge applications in various diseases, are the unique selling point (USP) of this book, setting it apart from the available books. Furthermore, it explores the exciting frontiers of anticancerous and antidiabetic molecules derived from plants.Key Features: Focus on advancements in extraction techniques for phytochemicals. Recent advances in understanding the pharmacological effects of primary and secondary metabolites Analysis of structure-activity relationships of biomolecules Future directions for integrating natural therapies into modern medicine Role of plants in homeopathic and Ayurvedic treatments Application of computational and AI techniques in phytochemistry Comprehensive review of anticancer biomolecules in the Simaroubaceae family Importance of dose-dependent studies for medicinal extracts Exploration of herbal remedies for ulcers and ocular diseases This book offers a comprehensive and insightful perspective on the therapeutic potential of plant-derived molecules and serves as an invaluable resource for researchers, students, and healthcare professionals interested in the pharmacology of plants and the development of novel therapeutics from natural sources.

This book, Pharmacology of Plants and Plant Derived Biologically Active Molecules, delves into the interesting world of phytochemicals and their therapeutic applications. It explores the journey from traditional medicine practices such as Ayurveda to modern scientific understanding, providing a comprehensive analysis of the chemistry, pharmacology, and therapeutic potential of plant-derived compounds. The detailed discussions on recent advancements and future directions in the field of pharmacology of plants, including novel extraction techniques, structure-activity relationship studies, and cutting-edge applications in various diseases, are the unique selling point (USP) of this book, setting it apart from the available books. Furthermore, it explores the exciting frontiers of anticancerous and antidiabetic molecules derived from plants.Key Features: Focus on advancements in extraction techniques for phytochemicals. Recent advances in understanding the pharmacological effects of primary and secondary metabolites Analysis of structure-activity relationships of biomolecules Future directions for integrating natural therapies into modern medicine Role of plants in homeopathic and Ayurvedic treatments Application of computational and AI techniques in phytochemistry Comprehensive review of anticancer biomolecules in the Simaroubaceae family Importance of dose-dependent studies for medicinal extracts Exploration of herbal remedies for ulcers and ocular diseases This book offers a comprehensive and insightful perspective on the therapeutic potential of plant-derived molecules and serves as an invaluable resource for researchers, students, and healthcare professionals interested in the pharmacology of plants and the development of novel therapeutics from natural sources.

This book explores the therapeutic potential of everyday kitchen ingredients, blending traditional practices with modern scientific analysis. It provides insights beyond the regular culinary use of vegetables and spices, and presents a comprehensive analysis of their chemistry, nutraceutical roles, and pharmacological applications. The diverse range of topics will offer readers a glimpse into the profound medicinal benefits these ingredients hold.With contributions from leading researchers at eminent institutions, the book encompasses the therapeutic potential of daily-use kitchen ingredients, their importance in historical and cultural contexts, and their relevance in modern medicine. This volume will help to reveal the true power of kitchen ingredients through scientific evidence.Key features include: A diverse range of topics on the therapeutic roles and nutraceutical significance of vegetables such as garlic, spinach, capsicum, fennels, onion, leafy vegetables, and others. A comprehensive insight into the phytochemistry and pharmacology of spices such as clove, cinnamon, ginger, cumin, cardamom, nutmeg, asafoetida, thyme, and more. The utilization of different kitchen ingredients for nutraceutical purposes in addressing chronic illnesses such as cancer and diabetes. Insight into the pharmacological role of essential oils derived from spices. Comprehensive insights into allergenicity, toxicity profiles, and dose-dependent studies. A detailed discussion on clinical evidence of assessments done on functional spices. This book is an essential resource for students, researchers, faculties, and healthcare professionals working in naturopathy. Exploration of the Medicinal Potential of Kitchen Ingredients promises to inspire innovative solutions and expand horizons in the fields of pharmacology and natural therapeutics.

Plant-Associated Medicinal Nano-Chemistry is a collection of 15 meticulously curated chapters that interconnects the transformative synergy between plant-derived bioactives and advanced nanotechnological platforms. This book reveals the pathways of green nanoparticle synthesis from plant sources, charting a dense trajectory through their complex applications-from targeted drug release and biosensing to innovative food preservation methods. A necessity for nanomedicine and pharmacognosy visionaries, and environmentally aware chemists, this handbook blends innovation and sustainability.Salient features: The book delivers holistic and in-depth coverage of plant-mediated nanoparticle synthesis with detailed descriptions of biomedical, therapeutic, and diagnostic applications Interdisciplinary integration of various themes related to nanotech, phytochemistry, molecular biology, toxicology, biosensing, food science, and regulatory affairs offers a truly rational approach Inclusion of topics such as nanocellulose production, noscapine-potentiated cancer therapies, and real-time detection of molecular hazards highlights the pioneering innovations in the field of drug development Each chapter reflects the latest experimental findings and theoretical frameworks enriched by the insights of domain experts and promises to deliver scholar-driven excellence Chapters on eco-friendly synthesis routes, emphasizing biodegradable technologies, minimal environmental impact, and ethical standards in nano-biomedicine, support the idea of sustainability

Plant-Associated Medicinal Nano-Chemistry is a collection of 15 meticulously curated chapters that interconnects the transformative synergy between plant-derived bioactives and advanced nanotechnological platforms. This book reveals the pathways of green nanoparticle synthesis from plant sources, charting a dense trajectory through their complex applications-from targeted drug release and biosensing to innovative food preservation methods. A necessity for nanomedicine and pharmacognosy visionaries, and environmentally aware chemists, this handbook blends innovation and sustainability.Salient features: The book delivers holistic and in-depth coverage of plant-mediated nanoparticle synthesis with detailed descriptions of biomedical, therapeutic, and diagnostic applications Interdisciplinary integration of various themes related to nanotech, phytochemistry, molecular biology, toxicology, biosensing, food science, and regulatory affairs offers a truly rational approach Inclusion of topics such as nanocellulose production, noscapine-potentiated cancer therapies, and real-time detection of molecular hazards highlights the pioneering innovations in the field of drug development Each chapter reflects the latest experimental findings and theoretical frameworks enriched by the insights of domain experts and promises to deliver scholar-driven excellence Chapters on eco-friendly synthesis routes, emphasizing biodegradable technologies, minimal environmental impact, and ethical standards in nano-biomedicine, support the idea of sustainability

This book explores the therapeutic potential of everyday kitchen ingredients, blending traditional practices with modern scientific analysis. It provides insights beyond the regular culinary use of vegetables and spices, and presents a comprehensive analysis of their chemistry, nutraceutical roles, and pharmacological applications. The diverse range of topics will offer readers a glimpse into the profound medicinal benefits these ingredients hold.With contributions from leading researchers at eminent institutions, the book encompasses the therapeutic potential of daily-use kitchen ingredients, their importance in historical and cultural contexts, and their relevance in modern medicine. This volume will help to reveal the true power of kitchen ingredients through scientific evidence.Key features include: A diverse range of topics on the therapeutic roles and nutraceutical significance of vegetables such as garlic, spinach, capsicum, fennels, onion, leafy vegetables, and others. A comprehensive insight into the phytochemistry and pharmacology of spices such as clove, cinnamon, ginger, cumin, cardamom, nutmeg, asafoetida, thyme, and more. The utilization of different kitchen ingredients for nutraceutical purposes in addressing chronic illnesses such as cancer and diabetes. Insight into the pharmacological role of essential oils derived from spices. Comprehensive insights into allergenicity, toxicity profiles, and dose-dependent studies. A detailed discussion on clinical evidence of assessments done on functional spices. This book is an essential resource for students, researchers, faculties, and healthcare professionals working in naturopathy. Exploration of the Medicinal Potential of Kitchen Ingredients promises to inspire innovative solutions and expand horizons in the fields of pharmacology and natural therapeutics.

We are extremely happy to introduce our new book, Recent Advances in Computer Aided Drug Designing. While interacting with many researchers in the field of biotechnology and allied sciences, we felt that there was need for a book that could easily bridge the gap between in silico methods applied in structural bioinformatics for drug designing and wet lab workers. Today, when computational skills in biology and biomedical research are in high demand, this book presents updated content for methods and tools applicable in modern computer-aided drug designing. Researchers are pouring knowledge into databases that are publicly available and laboratories across the globe are accessing this information for analysis and further investigation. There is a battery of data scientists involved in development and maintenance of online databases. Alongside them, there is another class of programmers and scientists involved in development of software tools for analysis of this data. Modern tools based on machine learning are available to provide accuracy and efficiency with speedy analysis of biological and biomedical data. In many cases, analysis of readily available biological data helps to decide future directions for laboratory work. Indications obtained from such analytics save time and resources which could be very crucial in general. Publicly available protein three-dimensional structure and drug databank libraries have facilitated the drug discovery process. Millions of drugs can be screened in a few hours by using virtual screening tools. Molecular viewing tools can be used to visualize macromolecules and their interactions with drugs. Findings from such studies are being used to validate results directly in laboratories. Efforts have been made to cover all areas relevant for computer-aided drug designing to allow this book to serve as a standard reference book and meet the requirements of graduate students and researchers working in drug design and structural bioinformatics. Some chapters are dedicated to basic concepts in computer-aided drug discovery while other chapters present applications of the available tools in the field. Contents from exemplary method-based chapters are easy to follow and will help new researchers in applying contemporary tools for their studies. The book will also stimulate programmers and data scientists interested in developing tools for structural bioinformatics applications to develop new and improved versions of software. Chapters presenting the basic concepts of methods involved in drug design will help new learners in the field to meet the challenges of designing novel therapeutics by using computational tools. Cross-disciplinary research is in trend nowadays and such investigations involving experts of their respective fields are highly promising and fruitful. Drug discovery requires experts from health sciences and medical sciences, molecular biologists, bioinformaticians, biotechnologists, biochemists, statisticians, biophysicists and clinicians. For a complete piece of translated product such as a drug, inputs from specialist researchers are needed. Modern rational drug discovery approaches are truly inter-disciplinary fields which require a systems biology approach for successful ventures. This book covers all steps of drug design, from drug target identification to intermediate steps to successful clinical trials, making it truly essential for modern researchers in the drug discovery and structural bioinformatics fields.