Beth Shapiro - Böcker

An insider's view on bringing extinct species back to lifeCould extinct species, like mammoths and passenger pigeons, be brought back to life? In How to Clone a Mammoth, Beth Shapiro, an evolutionary biologist and pioneer in ancient DNA research, addresses this intriguing question by walking readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used to resurrect the past. Considering de-extinction's practical benefits and ethical challenges, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.

From the very first dog to glowing fish and designer pigs – the human history of remaking nature‘Enlightening… Big history meets big science – and it’s great entertainment.’ THE TIMES, BEST BOOKS OF 2021Malaria-free mosquitoes, resurrected dinosaurs and woolly mammoths, designer humans – such is the power of the science of tomorrow. But the idea that humans have only recently begun to tinker with the natural world is false. We’ve been meddling with nature since the last ice age, we’re just getting a lot better at it.Drawing on decades of research, Beth Shapiro reveals the surprisingly long history of human intervention in evolution – for good and for ill – and looks ahead to the future, casting aside scaremongering myths about the dangers of interference. New biotechnologies can present us with the chance to improve our own lives, and increase the likelihood that we will continue to live in a rich and biologically diverse world.‘Very few people write about the insane complexities and power of biology with greater clarity, insight and levity than Beth Shapiro.’ ADAM RUTHERFORD, AUTHOR OF A BRIEF HISTORY OF EVERYONE WHO EVER LIVED

Research into ancient DNA began more than 25 years ago with the publication of short mitochondrial DNA sequence fragments from the quagga, an extinct relative of the zebra.

This fully updated second edition explores protocols that address the most challenging aspects of experimental work in ancient DNA, such as preparing ancient samples for DNA extraction, the DNA extraction itself, and transforming extracted ancient DNA molecules for sequencing library preparation. The volume also examines the analysis of high-throughput sequencing data recovered from ancient specimens, which, because of the degraded nature of ancient DNA and common co-extraction of contaminant DNA, has challenges that are unique compared to data recovered from modern specimens.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Ancient DNA: Methods and Protocols, Second Edition aims to serve both experts and beginners by presenting protocols in a manner that makes them easily accessible for everyday use in the lab.