Bhupendra Koul – författare

This book presents a comprehensive collection of various in situ and ex-situ soil remediation regimes that employ natural or genetically modified microbes, plants, and animals for the biodegradation of toxic compounds or hazardous waste into simpler non-toxic products. These techniques are demonstrated to be functionally effective in connection with physical, chemical, and biological strategies.

Soil and water contamination through heavy metals, hydrocarbons and radioactive wastes is of global concern, as these factors have cumulative effects on the environment and human health through food-chain contamination. The book discusses the utilization of algae, plants, plant-associated bacteria, fungi (endophytic or rhizospheric) and certain lower animals for the sustainable bioremediation of organic and inorganic pollutants.  In addition, it explores a number of more recent techniques like biochar and biofilms for carbon sequestration, soil conditioning and remediation, and water remediation. It highlights a number of recent advances in nanobioremediation, an emerging technology based on biosynthetic nanoparticles. Lastly, it presents illustrative case studies and highlights the successful treatment of polluted soils by means of these strategies.

This book presents up-to-date information on various vector-less/direct (physical, chemical) and vector-mediated/indirect (Agrobacterium-mediated) plant transformation techniques. It summarizes various strategies that facilitate a gene from lower organism to be expressed in higher plants and also in silico designing of synthetic gene for higher expression. It also highlights the importance of strong promoters to drive the expression of transgene(s). This book encompasses the advantages and drawbacks of cisgenesis and transgenesis, their implications towards sustainable crop improvement, and their future prospects. The importance, limitations, challenges, recent developments, and future prospects of molecular pharming is also discussed.  The book concludes with a chapter that summarizes the major contribution of GM-crops towards global food security and economy, advances in genome editing for crop improvement, challenges and risk associated with therelease of GM-crops, and the future of GM technology.

This book is meant for students and researchers in the field of life sciences, food science, and agriculture. 

This book provides detailed information on the various types of cancer, etiology, effects, and challenges associated with current cancer treatment regimes. The present edition has been written to reflect recent developments, success rates and lacunae in herbal and modern cancer therapies. It also describes the use of several herbal formulations to boost patients’ immunity, in order to prevent or help them cope with several cancers. The book highlights several herbs/shrubs/trees that have been reported to possess anti-cancer properties, paving the way for in-depth research into the dose standardization and efficacy of plant-based bioactive molecules. It also focuses on the sustainable conservation of medicinal flora, so that, in future, novel biomolecules be extracted and made available for the treatment of various cancers.

Given its highly relevant content, the book will benefit the entire cancer research community (students, scientists, pharmacists, herbalists and lecturers) at universities, research institutions and industry in the areas of oncology, herbal cancer therapy, biotechnology, drug discovery, pharmaceuticals, agriculture, and various disciplines of the biomedical sciences. 

This edited volume presents recent advancements in genetic transformation and genome editing, offering a comprehensive understanding of their applications for creating more sustainable crops. These innovations are revolutionizing crop development, enhancing yields, and mitigating environmental challenges.

The demand for sustainable crop production, driven by a growing global population and mounting environmental challenges, has never been more pressing. Genetic transformation and genome editing techniques offer precise and targeted ways to enhance crop traits, increase yields, and reduce the need for chemical inputs. The book traces the evolution of these technologies, from the early days of genetic modification to the current era of CRISPR-based genome editing. It covers cutting-edge technologies, from CRISPR-Cas9 to advanced gene editing techniques, while discussing the current scenario and future prospects of GM crops developed either by transgenic or genome editing approaches. The book explores the ethical and regulatory aspects surrounding genetic transformation, providing a complete perspective on this evolving domain.

It is an essential read for researchers, students, and professionals in the fields of agriculture, plant sciences, biotechnology, agronomy, as well as policymakers.

This edited book support Sustainable Development Goal 2 (SDG 2): Zero Hunger. This book summarizes the contribution of genetic engineering for sustainable crop improvement toward global food and health security, climate resilience and economic growth. The book acts as a compendium of research reports on recent developments in the arena of cisgenics or transgenics or genome editing of crop plants for tolerance to biotic or abiotic stresses, introgression of value-added traits, molecular pharming etc. Sustainable crop productivity, yield and nutrition are the major constrain for food and nutritional security for the human population especially, in developing countries where arable land per capita is shrinking while the human population is steadily increasing. Zero hunger and achieving food security is the top priority of the United Nations development goals. This book explains various methods of genetic transformation such as transgenic, cisgenic, and genome editing for crop improvement. It also encompasses the advantages of genetic engineering in plants and their scope for sustainable crop improvement. The importance, limitations, challenges, GM biosafety regulations, recent advancements and future prospects of GM crops are covered in various chapters. This book is of interest to teachers, researchers, plant tissue culturists, GM crop experts, research scholars, academicians, plant breeders, policymakers etc. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences. National and international agricultural scientists and policymakers will also find this to be a useful read.