This textbook provides a comprehensive, state of the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in GIST. The book  reviews new data about risk factors for the disease, profiles the new staging system for GIST, highlights our current understanding of genetic mutations that lead to GIST, and provides new perspectives about imaging of  GIST tumors. For localized disease, a greater appreciation of organ-sparing approaches and the importance of preservation of gastrointestinal function is discussed in detail, and advances in surgical techniques are highlighted, including minimally invasive surgery. For metastatic disease, the molecular biology of GIST is reviewed in a detailed and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. Several landmark trials have been published in the last few years and are placed incontext with respect to current management. Integration of surgery and systemic therapy through consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain are also discussed.   Gastrointestinal Stromal Tumors: Bench to Bedside will serve as a very useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

This textbook provides a comprehensive, state of the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in GIST. The book  reviews new data about risk factors for the disease, profiles the new staging system for GIST, highlights our current understanding of genetic mutations that lead to GIST, and provides new perspectives about imaging of  GIST tumors. For localized disease, a greater appreciation of organ-sparing approaches and the importance of preservation of gastrointestinal function is discussed in detail, and advances in surgical techniques are highlighted, including minimally invasive surgery. For metastatic disease, the molecular biology of GIST is reviewed in a detailed and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. Several landmark trials have been published in the last few years and are placed incontext with respect to current management. Integration of surgery and systemic therapy through consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain are also discussed.   Gastrointestinal Stromal Tumors: Bench to Bedside will serve as a very useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

The landscape of academic surgery has become increasingly complex.  Young academic surgeons are now confronted with the task of juggling administrative, clinical, educational, and research responsibilities.  While decades ago young faculty would look toward a single “triple threat” mentor, trainees and young junior faculty now must assemble a team of mentors who can help him/her craft a career trajectory for success in academia.  In addition, with the emergence of team based science and an emphasis on clinical “crew management” faculty now must hone their leadership skills to be effective in the research and clinical environment. While many books focus on specific research or technical surgical topics, there is a need for an accessible, user-friendly text on the subject of surgical mentorship and leadership. In particular, there is a strong desire among trainees and young surgeons to learn about mentorship, as well as define leadershiptools. Currently, there is a gap in the market for a definitive reference on surgical leadership and mentorship. This text will provide a comprehensive, state-of-the art definitive reference on surgical mentorship and leadership. The book will provide a practical, useful guide that reviews select topics on leadership and mentorship, as well as provide key information on how to launch a successful “young” surgical career. This text will focus on key points on how to identify mentors, highlight mentor-mentee “pearls”, as well as define key leadership traits in being successful as an academic surgeon.This text will serve as a very useful resource for young surgical faculty, as well as fellows and residents in a broad array of surgical training programs. Chapters will have multiple “call out” boxes to highlight key lessons learned, as well as provide mentorship and leadership “pearls.”  All chapters will be written by experts in their field and will include the most up-to-date information from national and international leaders.

The landscape of academic surgery has become increasingly complex.  Young academic surgeons are now confronted with the task of juggling administrative, clinical, educational, and research responsibilities.  While decades ago young faculty would look toward a single “triple threat” mentor, trainees and young junior faculty now must assemble a team of mentors who can help him/her craft a career trajectory for success in academia.  In addition, with the emergence of team based science and an emphasis on clinical “crew management” faculty now must hone their leadership skills to be effective in the research and clinical environment. While many books focus on specific research or technical surgical topics, there is a need for an accessible, user-friendly text on the subject of surgical mentorship and leadership. In particular, there is a strong desire among trainees and young surgeons to learn about mentorship, as well as define leadershiptools. Currently, there is a gap in the market for a definitive reference on surgical leadership and mentorship. This text will provide a comprehensive, state-of-the art definitive reference on surgical mentorship and leadership. The book will provide a practical, useful guide that reviews select topics on leadership and mentorship, as well as provide key information on how to launch a successful “young” surgical career. This text will focus on key points on how to identify mentors, highlight mentor-mentee “pearls”, as well as define key leadership traits in being successful as an academic surgeon.This text will serve as a very useful resource for young surgical faculty, as well as fellows and residents in a broad array of surgical training programs. Chapters will have multiple “call out” boxes to highlight key lessons learned, as well as provide mentorship and leadership “pearls.”  All chapters will be written by experts in their field and will include the most up-to-date information from national and international leaders.

This textbook provides a comprehensive, state of the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in GIST. The book  reviews new data about risk factors for the disease, profiles the new staging system for GIST, highlights our current understanding of genetic mutations that lead to GIST, and provides new perspectives about imaging of  GIST tumors. For localized disease, a greater appreciation of organ-sparing approaches and the importance of preservation of gastrointestinal function is discussed in detail, and advances in surgical techniques are highlighted, including minimally invasive surgery. For metastatic disease, the molecular biology of GIST is reviewed in a detailed and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. Several landmark trials have been published in the last few years and are placed incontext with respect to current management. Integration of surgery and systemic therapy through consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain are also discussed.   Gastrointestinal Stromal Tumors: Bench to Bedside will serve as a very useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

This textbook provides a comprehensive, state of the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in GIST. The book  reviews new data about risk factors for the disease, profiles the new staging system for GIST, highlights our current understanding of genetic mutations that lead to GIST, and provides new perspectives about imaging of  GIST tumors. For localized disease, a greater appreciation of organ-sparing approaches and the importance of preservation of gastrointestinal function is discussed in detail, and advances in surgical techniques are highlighted, including minimally invasive surgery. For metastatic disease, the molecular biology of GIST is reviewed in a detailed and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. Several landmark trials have been published in the last few years and are placed incontext with respect to current management. Integration of surgery and systemic therapy through consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain are also discussed.   Gastrointestinal Stromal Tumors: Bench to Bedside will serve as a very useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

The landscape of academic surgery has become increasingly complex.  Young academic surgeons are now confronted with the task of juggling administrative, clinical, educational, and research responsibilities.  While decades ago young faculty would look toward a single “triple threat” mentor, trainees and young junior faculty now must assemble a team of mentors who can help him/her craft a career trajectory for success in academia.  In addition, with the emergence of team based science and an emphasis on clinical “crew management” faculty now must hone their leadership skills to be effective in the research and clinical environment. While many books focus on specific research or technical surgical topics, there is a need for an accessible, user-friendly text on the subject of surgical mentorship and leadership. In particular, there is a strong desire among trainees and young surgeons to learn about mentorship, as well as define leadershiptools. Currently, there is a gap in the market for a definitive reference on surgical leadership and mentorship. This text will provide a comprehensive, state-of-the art definitive reference on surgical mentorship and leadership. The book will provide a practical, useful guide that reviews select topics on leadership and mentorship, as well as provide key information on how to launch a successful “young” surgical career. This text will focus on key points on how to identify mentors, highlight mentor-mentee “pearls”, as well as define key leadership traits in being successful as an academic surgeon.This text will serve as a very useful resource for young surgical faculty, as well as fellows and residents in a broad array of surgical training programs. Chapters will have multiple “call out” boxes to highlight key lessons learned, as well as provide mentorship and leadership “pearls.”  All chapters will be written by experts in their field and will include the most up-to-date information from national and international leaders.

The landscape of academic surgery has become increasingly complex.  Young academic surgeons are now confronted with the task of juggling administrative, clinical, educational, and research responsibilities.  While decades ago young faculty would look toward a single “triple threat” mentor, trainees and young junior faculty now must assemble a team of mentors who can help him/her craft a career trajectory for success in academia.  In addition, with the emergence of team based science and an emphasis on clinical “crew management” faculty now must hone their leadership skills to be effective in the research and clinical environment. While many books focus on specific research or technical surgical topics, there is a need for an accessible, user-friendly text on the subject of surgical mentorship and leadership. In particular, there is a strong desire among trainees and young surgeons to learn about mentorship, as well as define leadershiptools. Currently, there is a gap in the market for a definitive reference on surgical leadership and mentorship. This text will provide a comprehensive, state-of-the art definitive reference on surgical mentorship and leadership. The book will provide a practical, useful guide that reviews select topics on leadership and mentorship, as well as provide key information on how to launch a successful “young” surgical career. This text will focus on key points on how to identify mentors, highlight mentor-mentee “pearls”, as well as define key leadership traits in being successful as an academic surgeon.This text will serve as a very useful resource for young surgical faculty, as well as fellows and residents in a broad array of surgical training programs. Chapters will have multiple “call out” boxes to highlight key lessons learned, as well as provide mentorship and leadership “pearls.”  All chapters will be written by experts in their field and will include the most up-to-date information from national and international leaders.