Edited by two leading orthopaedic surgeons specializing in the treatment of haemophilia, and an acclaimed haematologist, Musculoskeletal Aspects of Haemophilia draws together, within a single volume, all the information needed for the practical treatment of the musculoskeletal complications of haemophilia.

A practical ''hands on'' guide designed for use on the ward, in the office and at the computer, this book draws on the experience not only of two major centres (Madrid, Spain and London, UK) but also of numerous specialists worldwide. In addition to orthopaedic surgery, it also covers research, rehabilitation and physiotherapy.

While of primary interest to the orthopaedic surgeon, rheumatologist, physiatrist and physiotherapist, this book will also be relevant to the haematologist responsible for the care of the haemophiliac patient.

Edited by an orthopaedic surgeon and a haematologist who are leading specialists in the treatment of haemophilia, Inhibitors in Patients with Haemophilia reviews the different haemostatic products and protocols for the control of bleeding and surgery in haemophilic patients with inhibitors.

The book draws together in a single volume all of the clinical issues involved in the treatment of inhibitors from numerous specialists worldwide. It will be an invaluable resource for all those treating inhibitors in people with haemophilia.

Edited by an orthopaedic surgeon and a haematologist who are leading specialists in the treatment of haemophilia, Inhibitors in Patients with Haemophilia reviews the different haemostatic products and protocols for the control of bleeding and surgery in haemophilic patients with inhibitors.The book draws together in a single volume all of the clinical issues involved in the treatment of inhibitors from numerous specialists worldwide. It will be an invaluable resource for all those treating inhibitors in people with haemophilia.

Textbook of Hemophilia, 3rd editionEdited byChristine A. Lee, MA, MD, DSc, FRCP, FRCPath, FRCOGEmeritus Professor of Haemophilia, University of London, London, UKErik E. Berntorp, MD, PhDProfessor of Coagulation Medicine, Lund UniversityMalmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, SwedenW. Keith Hoots, MDDirector, Division of Blood Diseases and Resources, National Heart, Lung and Blood InstituteNational Institutes of Health, Bethesda, MD;Professor of Pediatrics and Internal Medicine, University of Texas Medical School at Houston, Houston, TX, USAWithout doubt, Textbook of Hemophilia, 3rd edition is the definitive reference source on all aspects of haemophilia including diagnosis, management and treatment. Edited by three, world-renowned experts on haemophilia, this completely revised resource features chapters written by over 60 international contributors with international expertise in caring for haemophilia patients.Textbook of Hemophilia, 3rd edition Features eight new chapters, covering individualised dosing, vCJD and haemophilia, new drugs in the pipeline, and surgery in inhibitor patientsPresents new developments, such as gene therapyHighlights controversial issues and provides advice for everyday clinical questionsRepresents essential reading for all healthcare professionals involved in the care of those with haemophiliaTitles of related interestHemophilia and Hemostasis: A Case-Based Approach to Management, 2nd Editionhttp://eu.wiley.com/WileyCDA/Section/id-302479.html, ISBN: 9780470659762Current and Future Issues in Hemophilia Carehttp://eu.wiley.com/WileyCDA/Section/id-302479.html?query=E.+Carlos+Rodriguez-Merchan, ISBN: 9780470670576http://www.wiley.com/go/hematology

Textbook of Hemophilia, 3rd edition

Edited by Christine A. Lee, MA, MD, DSc, FRCP, FRCPath, FRCOG Emeritus Professor of Haemophilia, University of London, London, UK

Erik E. Berntorp, MD, PhD Professor of Coagulation Medicine, Lund University Malmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, Sweden

W. Keith Hoots, MD Director, Division of Blood Diseases and Resources, National Heart, Lung and Blood Institute National Institutes of Health, Bethesda, MD; Professor of Pediatrics and Internal Medicine, University of Texas Medical School at Houston, Houston, TX, USA

Without doubt, Textbook of Hemophilia, 3rd edition is the definitive reference source on all aspects of haemophilia including diagnosis, management and treatment. Edited by three, world-renowned experts on haemophilia, this completely revised resource features chapters written by over 60 international contributors with international expertise in caring for haemophilia patients.

Textbook of Hemophilia, 3rd edition

Features eight new chapters, covering individualised dosing, vCJD and haemophilia, new drugs in the pipeline, and surgery in inhibitor patients Presents new developments, such as gene therapy Highlights controversial issues and provides advice for everyday clinical questions Represents essential reading for all healthcare professionals involved in the care of those with haemophilia

 Titles of related interest

 Hemophilia and Hemostasis: A Case-Based Approach to Management, 2nd Edition

Ma, ISBN: 9780470659762

Current and Future Issues in Hemophilia Care

Rodriguez-Merchan, ISBN: 9780470670576

www.wiley.com/go/hematology

Textbook of Hemophilia, 3rd edition

Edited by Christine A. Lee, MA, MD, DSc, FRCP, FRCPath, FRCOG Emeritus Professor of Haemophilia, University of London, London, UK

Erik E. Berntorp, MD, PhD Professor of Coagulation Medicine, Lund University Malmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, Sweden

W. Keith Hoots, MD Director, Division of Blood Diseases and Resources, National Heart, Lung and Blood Institute National Institutes of Health, Bethesda, MD; Professor of Pediatrics and Internal Medicine, University of Texas Medical School at Houston, Houston, TX, USA

Without doubt, Textbook of Hemophilia, 3rd edition is the definitive reference source on all aspects of haemophilia including diagnosis, management and treatment. Edited by three, world-renowned experts on haemophilia, this completely revised resource features chapters written by over 60 international contributors with international expertise in caring for haemophilia patients.

Textbook of Hemophilia, 3rd edition

Features eight new chapters, covering individualised dosing, vCJD and haemophilia, new drugs in the pipeline, and surgery in inhibitor patients Presents new developments, such as gene therapy Highlights controversial issues and provides advice for everyday clinical questions Represents essential reading for all healthcare professionals involved in the care of those with haemophilia

 Titles of related interest

 Hemophilia and Hemostasis: A Case-Based Approach to Management, 2nd Edition

Ma, ISBN: 9780470659762

Current and Future Issues in Hemophilia Care

Rodriguez-Merchan, ISBN: 9780470670576

www.wiley.com/go/hematology

The essential guide for understanding and treating women with inherited bleeding disorders, revised and updatedNow in its second edition, Inherited Bleeding Disorders in Women includes the most recent developments and research in the field. This important guide offers the most current information available for the effective management of these complex and difficult to diagnose disorders. Treating women with inherited bleeding disorders can be challenging and requires close collaboration among practitioners in different specialties.This important guide is written by a team of international experts who offer advice and practical suggestions for treating women with inherited bleeding disorders. Inherited Bleeding Disorders in Women comprehensively covers obstetric and gynecological issues for carriers of hemophilia, women with von Willebrand disease, rare bleeding disorders and inherited platelet disorders. This important resource: Offers an updated guide for hematologists, obstetricans and gynecologists and other clinicians treating women with inherited bleeding disordersIncludes information for treating both common and rare bleeding disordersContains the most recent developments and advances in the field for the treatment and management of inherited bleeding disorders in womenPresents information from noted experts in the fieldOffers a multidisciplinary approach to the topicWritten for hematologists, obstetricians and gynecologists and other clinicians working with women, Inherited Bleeding Disorders in Women has been fully revised and updated and continues to serve as a trusted guide for the management and treatment of women with inherited bleeding disorders.

The essential guide for understanding and treating women with inherited bleeding disorders, revised and updated

Now in its second edition, Inherited Bleeding Disorders in Women includes the most recent developments and research in the field. This important guide offers the most current information available for the effective management of these complex and difficult to diagnose disorders. Treating women with inherited bleeding disorders can be challenging and requires close collaboration among practitioners in different specialties.

This important guide is written by a team of international experts who offer advice and practical suggestions for treating women with inherited bleeding disorders. Inherited Bleeding Disorders in Women comprehensively covers obstetric and gynecological issues for carriers of hemophilia, women with von Willebrand disease, rare bleeding disorders and inherited platelet disorders. This important resource:

Offers an updated guide for hematologists, obstetricans and gynecologists and other clinicians treating women with inherited bleeding disorders Includes information for treating both common and rare bleeding disorders Contains the most recent developments and advances in the field for the treatment and management of inherited bleeding disorders in women Presents information from noted experts in the field Offers a multidisciplinary approach to the topic

Written for hematologists, obstetricians and gynecologists and other clinicians working with women, Inherited Bleeding Disorders in Women has been fully revised and updated and continues to serve as a trusted guide for the management and treatment of women with inherited bleeding disorders. 

The essential guide for understanding and treating women with inherited bleeding disorders, revised and updated

Now in its second edition, Inherited Bleeding Disorders in Women includes the most recent developments and research in the field. This important guide offers the most current information available for the effective management of these complex and difficult to diagnose disorders. Treating women with inherited bleeding disorders can be challenging and requires close collaboration among practitioners in different specialties.

This important guide is written by a team of international experts who offer advice and practical suggestions for treating women with inherited bleeding disorders. Inherited Bleeding Disorders in Women comprehensively covers obstetric and gynecological issues for carriers of hemophilia, women with von Willebrand disease, rare bleeding disorders and inherited platelet disorders. This important resource:

Offers an updated guide for hematologists, obstetricans and gynecologists and other clinicians treating women with inherited bleeding disorders Includes information for treating both common and rare bleeding disorders Contains the most recent developments and advances in the field for the treatment and management of inherited bleeding disorders in women Presents information from noted experts in the field Offers a multidisciplinary approach to the topic

Written for hematologists, obstetricians and gynecologists and other clinicians working with women, Inherited Bleeding Disorders in Women has been fully revised and updated and continues to serve as a trusted guide for the management and treatment of women with inherited bleeding disorders. 

The only up-to-date definitive reference source on hemophilia

This book is an invaluable resource that provides an overview of all aspects of the care of patients with haemophilia.

Covering how to assess both bleeding children and adults, Haemophilia A and B, molecular basis of the disease, the role of factors in coagulation, epidemiology, pharmacokinetics, and treatment of inhibitors. There will also be a section on musculoskeletal aspects of haemophilia as well as newer developments such as gene therapy and rare bleeding disorders.

Textbook of Hemophilia is ideal for:

Trainees and residents in hematology Hematologists in practice Specialists working in thrombosis and hemostasis as well as transfusion medicine

Why Buy This Book?

Essential for all those managing hemophilia patients Detailed guidance on assessment, diagnosis, management and treatment Advice for everyday clinical questions Edited by three of the world’s leading experts on hemophilia

The Textbook of Hemophilia has become a definitive resource for all those managing hemophilia patients. It covers all the common and rare bleeding disorders, both in terms of clinical management as well as the genetic, laboratory, financial and psychological aspects.

This second edition covers all the latest developments in the field of hemophilia, with new chapters on:

the genetic and molecular basis of inherited blood disorders how to manage adolescent and older patients emergency medicine and inherited blood disorders national hemophilia databases

Drawing on the vast experience of the authors, the aim of this textbook remains the same - to improve the care of patients suffering from hemophilia. The book is full of detailed guidance and advice on everyday clinical questions making it invaluable to all trainee and practicing hematologists.

Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease.

This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding.

Written by an international team of contributors it describes the progress in, and difficulties of diagnosing phenotypes and genotypes. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy.

Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis.

Edited by two leading orthopaedic surgeons specializing in the treatment of haemophilia, and an acclaimed haematologist, Musculoskeletal Aspects of Haemophilia draws together, within a single volume, all the information needed for the practical treatment of the musculoskeletal complications of haemophilia.

A practical ''hands on'' guide designed for use on the ward, in the office and at the computer, this book draws on the experience not only of two major centres (Madrid, Spain and London, UK) but also of numerous specialists worldwide. In addition to orthopaedic surgery, it also covers research, rehabilitation and physiotherapy.

While of primary interest to the orthopaedic surgeon, rheumatologist, physiatrist and physiotherapist, this book will also be relevant to the haematologist responsible for the care of the haemophiliac patient.

Edited by an orthopaedic surgeon and a haematologist who are leading specialists in the treatment of haemophilia, Inhibitors in Patients with Haemophilia reviews the different haemostatic products and protocols for the control of bleeding and surgery in haemophilic patients with inhibitors.

The book draws together in a single volume all of the clinical issues involved in the treatment of inhibitors from numerous specialists worldwide. It will be an invaluable resource for all those treating inhibitors in people with haemophilia.

Edited by an orthopaedic surgeon and a haematologist who are leading specialists in the treatment of haemophilia, Inhibitors in Patients with Haemophilia reviews the different haemostatic products and protocols for the control of bleeding and surgery in haemophilic patients with inhibitors.The book draws together in a single volume all of the clinical issues involved in the treatment of inhibitors from numerous specialists worldwide. It will be an invaluable resource for all those treating inhibitors in people with haemophilia.

Textbook of Hemophilia, 3rd editionEdited byChristine A. Lee, MA, MD, DSc, FRCP, FRCPath, FRCOGEmeritus Professor of Haemophilia, University of London, London, UKErik E. Berntorp, MD, PhDProfessor of Coagulation Medicine, Lund UniversityMalmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, SwedenW. Keith Hoots, MDDirector, Division of Blood Diseases and Resources, National Heart, Lung and Blood InstituteNational Institutes of Health, Bethesda, MD;Professor of Pediatrics and Internal Medicine, University of Texas Medical School at Houston, Houston, TX, USAWithout doubt, Textbook of Hemophilia, 3rd edition is the definitive reference source on all aspects of haemophilia including diagnosis, management and treatment. Edited by three, world-renowned experts on haemophilia, this completely revised resource features chapters written by over 60 international contributors with international expertise in caring for haemophilia patients.Textbook of Hemophilia, 3rd edition Features eight new chapters, covering individualised dosing, vCJD and haemophilia, new drugs in the pipeline, and surgery in inhibitor patientsPresents new developments, such as gene therapyHighlights controversial issues and provides advice for everyday clinical questionsRepresents essential reading for all healthcare professionals involved in the care of those with haemophiliaTitles of related interestHemophilia and Hemostasis: A Case-Based Approach to Management, 2nd Editionhttp://eu.wiley.com/WileyCDA/Section/id-302479.html, ISBN: 9780470659762Current and Future Issues in Hemophilia Carehttp://eu.wiley.com/WileyCDA/Section/id-302479.html?query=E.+Carlos+Rodriguez-Merchan, ISBN: 9780470670576http://www.wiley.com/go/hematology

Textbook of Hemophilia, 3rd edition

Edited by Christine A. Lee, MA, MD, DSc, FRCP, FRCPath, FRCOG Emeritus Professor of Haemophilia, University of London, London, UK

Erik E. Berntorp, MD, PhD Professor of Coagulation Medicine, Lund University Malmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, Sweden

W. Keith Hoots, MD Director, Division of Blood Diseases and Resources, National Heart, Lung and Blood Institute National Institutes of Health, Bethesda, MD; Professor of Pediatrics and Internal Medicine, University of Texas Medical School at Houston, Houston, TX, USA

Without doubt, Textbook of Hemophilia, 3rd edition is the definitive reference source on all aspects of haemophilia including diagnosis, management and treatment. Edited by three, world-renowned experts on haemophilia, this completely revised resource features chapters written by over 60 international contributors with international expertise in caring for haemophilia patients.

Textbook of Hemophilia, 3rd edition

Features eight new chapters, covering individualised dosing, vCJD and haemophilia, new drugs in the pipeline, and surgery in inhibitor patients Presents new developments, such as gene therapy Highlights controversial issues and provides advice for everyday clinical questions Represents essential reading for all healthcare professionals involved in the care of those with haemophilia

 Titles of related interest

 Hemophilia and Hemostasis: A Case-Based Approach to Management, 2nd Edition

Ma, ISBN: 9780470659762

Current and Future Issues in Hemophilia Care

Rodriguez-Merchan, ISBN: 9780470670576

www.wiley.com/go/hematology

Textbook of Hemophilia, 3rd edition

Edited by Christine A. Lee, MA, MD, DSc, FRCP, FRCPath, FRCOG Emeritus Professor of Haemophilia, University of London, London, UK

Erik E. Berntorp, MD, PhD Professor of Coagulation Medicine, Lund University Malmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, Sweden

W. Keith Hoots, MD Director, Division of Blood Diseases and Resources, National Heart, Lung and Blood Institute National Institutes of Health, Bethesda, MD; Professor of Pediatrics and Internal Medicine, University of Texas Medical School at Houston, Houston, TX, USA

Without doubt, Textbook of Hemophilia, 3rd edition is the definitive reference source on all aspects of haemophilia including diagnosis, management and treatment. Edited by three, world-renowned experts on haemophilia, this completely revised resource features chapters written by over 60 international contributors with international expertise in caring for haemophilia patients.

Textbook of Hemophilia, 3rd edition

Features eight new chapters, covering individualised dosing, vCJD and haemophilia, new drugs in the pipeline, and surgery in inhibitor patients Presents new developments, such as gene therapy Highlights controversial issues and provides advice for everyday clinical questions Represents essential reading for all healthcare professionals involved in the care of those with haemophilia

 Titles of related interest

 Hemophilia and Hemostasis: A Case-Based Approach to Management, 2nd Edition

Ma, ISBN: 9780470659762

Current and Future Issues in Hemophilia Care

Rodriguez-Merchan, ISBN: 9780470670576

www.wiley.com/go/hematology

The essential guide for understanding and treating women with inherited bleeding disorders, revised and updatedNow in its second edition, Inherited Bleeding Disorders in Women includes the most recent developments and research in the field. This important guide offers the most current information available for the effective management of these complex and difficult to diagnose disorders. Treating women with inherited bleeding disorders can be challenging and requires close collaboration among practitioners in different specialties.This important guide is written by a team of international experts who offer advice and practical suggestions for treating women with inherited bleeding disorders. Inherited Bleeding Disorders in Women comprehensively covers obstetric and gynecological issues for carriers of hemophilia, women with von Willebrand disease, rare bleeding disorders and inherited platelet disorders. This important resource: Offers an updated guide for hematologists, obstetricans and gynecologists and other clinicians treating women with inherited bleeding disordersIncludes information for treating both common and rare bleeding disordersContains the most recent developments and advances in the field for the treatment and management of inherited bleeding disorders in womenPresents information from noted experts in the fieldOffers a multidisciplinary approach to the topicWritten for hematologists, obstetricians and gynecologists and other clinicians working with women, Inherited Bleeding Disorders in Women has been fully revised and updated and continues to serve as a trusted guide for the management and treatment of women with inherited bleeding disorders.

The essential guide for understanding and treating women with inherited bleeding disorders, revised and updated

Now in its second edition, Inherited Bleeding Disorders in Women includes the most recent developments and research in the field. This important guide offers the most current information available for the effective management of these complex and difficult to diagnose disorders. Treating women with inherited bleeding disorders can be challenging and requires close collaboration among practitioners in different specialties.

This important guide is written by a team of international experts who offer advice and practical suggestions for treating women with inherited bleeding disorders. Inherited Bleeding Disorders in Women comprehensively covers obstetric and gynecological issues for carriers of hemophilia, women with von Willebrand disease, rare bleeding disorders and inherited platelet disorders. This important resource:

Offers an updated guide for hematologists, obstetricans and gynecologists and other clinicians treating women with inherited bleeding disorders Includes information for treating both common and rare bleeding disorders Contains the most recent developments and advances in the field for the treatment and management of inherited bleeding disorders in women Presents information from noted experts in the field Offers a multidisciplinary approach to the topic

Written for hematologists, obstetricians and gynecologists and other clinicians working with women, Inherited Bleeding Disorders in Women has been fully revised and updated and continues to serve as a trusted guide for the management and treatment of women with inherited bleeding disorders. 

The essential guide for understanding and treating women with inherited bleeding disorders, revised and updated

Now in its second edition, Inherited Bleeding Disorders in Women includes the most recent developments and research in the field. This important guide offers the most current information available for the effective management of these complex and difficult to diagnose disorders. Treating women with inherited bleeding disorders can be challenging and requires close collaboration among practitioners in different specialties.

This important guide is written by a team of international experts who offer advice and practical suggestions for treating women with inherited bleeding disorders. Inherited Bleeding Disorders in Women comprehensively covers obstetric and gynecological issues for carriers of hemophilia, women with von Willebrand disease, rare bleeding disorders and inherited platelet disorders. This important resource:

Offers an updated guide for hematologists, obstetricans and gynecologists and other clinicians treating women with inherited bleeding disorders Includes information for treating both common and rare bleeding disorders Contains the most recent developments and advances in the field for the treatment and management of inherited bleeding disorders in women Presents information from noted experts in the field Offers a multidisciplinary approach to the topic

Written for hematologists, obstetricians and gynecologists and other clinicians working with women, Inherited Bleeding Disorders in Women has been fully revised and updated and continues to serve as a trusted guide for the management and treatment of women with inherited bleeding disorders. 

The only up-to-date definitive reference source on hemophilia

This book is an invaluable resource that provides an overview of all aspects of the care of patients with haemophilia.

Covering how to assess both bleeding children and adults, Haemophilia A and B, molecular basis of the disease, the role of factors in coagulation, epidemiology, pharmacokinetics, and treatment of inhibitors. There will also be a section on musculoskeletal aspects of haemophilia as well as newer developments such as gene therapy and rare bleeding disorders.

Textbook of Hemophilia is ideal for:

Trainees and residents in hematology Hematologists in practice Specialists working in thrombosis and hemostasis as well as transfusion medicine

Why Buy This Book?

Essential for all those managing hemophilia patients Detailed guidance on assessment, diagnosis, management and treatment Advice for everyday clinical questions Edited by three of the world’s leading experts on hemophilia

The Textbook of Hemophilia has become a definitive resource for all those managing hemophilia patients. It covers all the common and rare bleeding disorders, both in terms of clinical management as well as the genetic, laboratory, financial and psychological aspects.

This second edition covers all the latest developments in the field of hemophilia, with new chapters on:

the genetic and molecular basis of inherited blood disorders how to manage adolescent and older patients emergency medicine and inherited blood disorders national hemophilia databases

Drawing on the vast experience of the authors, the aim of this textbook remains the same - to improve the care of patients suffering from hemophilia. The book is full of detailed guidance and advice on everyday clinical questions making it invaluable to all trainee and practicing hematologists.

Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease.

This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding.

Written by an international team of contributors it describes the progress in, and difficulties of diagnosing phenotypes and genotypes. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy.

Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis.