Crosby - Böcker

Environmental toxicology and chemistry have become subjects of intense academic and public interest. This book is the first text to tie them closely together. It presents their principles and applications through numerous illustrative examples and special topics highlighting current environmental concerns. Intended for advanced undergraduate and graduate students, the book will also interest anyone desiring an update in these timely subjects.

The production of optically active intermediates and products as pure enantiomers is a topic of ever-increasing importance to the chemical industry. The economic incentives of improved cost efficiency and enhanced biological activity, together with new regulatory pressures have, in the last decade, brought about a dramatic increase in the number and scope of industrial processes. Chirality in Industry provides an overview of the production of optically active compounds on a large scale wholly from an industrial perspective. The volume includes example of each of the available process options, from classical resolution procedures to asymmetric syntheses with traditional chemical catalysts and enzyme-based technologies. An extended opening chapter, which systematically considers these options and relates them to a series of important targets, is followed by a series of more detailed case histories by industrial authors summarizing the processes which underpin the large-scale production of several important optically pure intermediates. While Chirality in Industry should prove of particular interest to chemists who are professionally involved in the production of pure enantiomers on a practical scale, it is hoped that students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of large scale thinking. An economic solution is more likely to be a simple, elegant solution.

This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own, Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals, agrochemicals, electronics, food, flavour and fragrance industries are all represented.Chirality in Industry II All new case historiesUnique industrial perspective on chiral technologyEmphasis on scale-up and process developmentComparison of biocatalysis, asymmetric synthesis and classical resolution approachesThe chiral infrastructure is now largely in place and there is no reason why large-scale production should not be possible for even moderately priced single enantiomer products. The successful industrial application of chiral chemistry depends on the integration of a range of supporting technologies and there are many examples in this volume of how widely the industrial practitioner must cast the net to achieve practical production methods. As with Volume I, this new volume is of particular interest to those professionally involved in the scale-up processes for single enantiomers. However, students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of large-scale thinking. An economic solution is still most likely to be a simple, elegant solution.

Sex Discrimination in the Workplace is an interdisciplinary volume that examines the various approaches to the study of sex discrimination and explores solutions and interventions. With riveting first-hand accounts from plaintiffs, lawyers and expert witnesses who have mounted battles against discriminatory employers, it is an invaluable resource for anyone seeking to gain a better understanding of precisely what sex discrimination is and what can be done to combat it. Examines sex discrimination through the eyes of law, economics, sociology, and psychology, providing expert descriptions of the fundamental research related to sex discrimination and their field Contains first hand accounts of sex discrimination cases, many of which relate to landmark contemporary incidents Concludes with solutions to the problems of discrimination from individual, organizational, and societal perspectives Written in clear, engaging prose with contributions from eminent scholars