David Kerr - Böcker

It’s almost impossible to overstate the benefits of creating a well-planned pond in your garden or field. This detailed and practical guide will give the novice and experienced gardener alike a straightforward explanation of how to plan, construct and plant a thriving pond, avoiding common problems and establishing a haven for wildlife.

Diabetes Digital Health brings together the multifaceted information surrounding the science of digital health from an academic, regulatory, industrial, investment and cybersecurity perspective. Clinicians and researchers who are developing and evaluating mobile apps for diabetes patients will find this essential reading, as will industry people whose companies are developing mobile apps and sensors.

Provides valuable information for clinicians, researchers and industry about the design and evaluation of patient-facing diabetes adherence technologies Highlights cutting-edge topics that are presented and discussed at the Digital Diabetes Congress

In the past 10 years the European Union and China have emerged as new international actors. They have an increasingly diverse relationship covering economy, politics, technology, culture and education; but beyond these two-way linkages the EU-China development is also changing the international political environment. One noted US scholar, David Shambaugh, has pointed to a new 'Strategic Triangle' between the US, EU, and China. Several other major actors such as Japan, India and Russia are also interested in the 'EU factor' in their relations with China; or the 'China factor' in their EU relations. This volume presents contributions from major scholars from Europe and China, which debate the nature, problems and potential of the emerging strategic relationship between the EU and China. Several papers develop new theoretical approaches to regionalism and inter-regionalism. The first major scholarly work to provide a comprehensive overview of EU-China relations and the wider international context, this volume will be essential reading for scholars and students of international relations and policy makers.

Recent advances in biology and immunology have opened up new horizons in both our understanding of cancer as a disease, and the potential for cancer therapy. These major developments mean that chemotherapy, radiotherapy and surgery are no longer the only options. Biotherapy, or biological therapy, is now regarded as the fourth treatment modality for patients with cancer. It utilises the great increase in our knowledge of molecular biology, cell biology and immunology to achieve tumour control. New biological agents are currently being used to treat cancer, such as monoclonal antibodies and vaccine therapies to stimulate the body's immune system to attack cancer cells. Biotherapy may be targeted to act specifically on cancer cells. Drugs such as monoclonal antibodies can be designed to recognize and find a particular type of cancer cell, attach itself to them, and destroy them. Naturally occuring biological molecules such as cytokines are also used, and the manipulation of normal biological mechanisms to control or inhibit tumour growth is another key feature of biotherapy. Edited by a team with perspectives in pharmacology, oncology and nursing, and with contributions from experts in the various areas of biotherapy, this book serves as an introduction to the subject. It includes the principles behind biological therapy, with discussion of the impact on the future of the fight against cancer. It has a strong clinical focus, describing the relevant biology and immunology while highlighting clinical relevance and treatment issues.

The treatment of cancer has undergone dramatic evolutions in the past two decades and the provision of holistic care by a multidisciplinary team of specialists is emerging as the cornerstone of recent improvements in outcome. Accompanying this multidisciplinary approach is the increasing complexity of therapeutic agents and modalities utilized. Drugs in Cancer Care is a succinct, practical and user-friendly guide to commonly used drugs and non-surgical therapeutic modalities in oncology. This detailed yet concise handbook contains over 90 monographs of cancer care providing the information needed to deliver chemotherapy with safety and precision, including information on mechanism of action, clinical pharmacology, side effect profile, tumour indications, combination treatment and how to respond to the hepato-renal impairment seen in many patients with advanced cancer.In an easy to use A-Z format this handbook will appeal to a variety of healthcare professional involved in the provision of cancer care and medicine information and will become an essential and well-thumbed item in every oncologist's toolkit.

Diabetes Digital Health and Telehealth explains, from technologic, economic and sociologic standpoints how digital health and telehealth have come to dominate the management of diabetes. The book also includes information on improved telemedicine tools and platforms for communicating with patients, reviewing medical records, and interpreting data from wearable devices. In addition, evolving wearable sensors such as continuous glucose monitors, closed loop automated insulin delivery systems, cuffless blood pressure monitors, exercise monitors and smart insulin pens are covered. Covers advances in the fields of digital health and telehealth, including research methods, relevant types of evidence, and viable endpoints for assessing the clinical and economic benefits of digital health and telehealth for diabetes Discusses improved telemedicine tools and platforms for communicating with patients, reviewing medical records and interpreting data from wearable devices Analyzes information gaps, research methods, relevant types of evidence, and viable endpoints for assessing the clinical and economic benefits of digital health and telehealth for diabetes

Citizenship through Secondary History reveals the potential of history to engage with citizenship education and includes:a review of the links between citizenship education and the teaching and learning of historyan analysis of how citizenship education is characterised, raising key issues about what could and should be achieveda critique of the discipline and the pitfalls to avoid in teaching citizenship through historycase studies offering practical teaching suggestions.History teaching is at the vanguard of citizenship education - the past is the springboard from which citizens learn to think and act. This book offers positive and direct ways to get involved in the thinking that must underpin any worthwhile citizenship education, for all professional teachers, student teachers in history, policy-makers, heads of department and principals.

Diabetes Digital Health, Telehealth, and Artificial Intelligence explains how to develop and use the emerging technologies of digital health, telehealth, and artificial intelligence to address this important public health problem to deliver new hardware, software, and processes. The book explores trends in developing and deploying the three most important emerging technologies for diabetes: digital health, telehealth, and artificial intelligence. This book is essential to clinicians, scientists, engineers, industry professionals, regulators, and investors, offering the tools that will be used to create the next generation products to support a precision medicine approach to manage diabetes.According to the CDC, in the US there are 37 million people with diabetes and 96 million people with prediabetes. Diabetes triples the risk of myocardial infarction and stroke and is the leading cause of blindness, end stage renal failure, and amputations. The management of diabetes is becoming increasingly dominated by digital health tools consisting of wearable sensors, mobile applications providing decision support software, and wireless communication tools. Digital health provides new data streams that can be combined to create unique approaches for diabetes based on a precision medicine paradigm.

Includes Artificial intelligence (AI) data for the prediction, diagnosis, treatment, and prognostication for diabetes as a model diseaseDescribes the most important issues of our time that comprise the most important technologies currently being applied to diabetesPresented in a consistent easy to help those new to the field understand and compare/contrast various elements of digital health, telehealth, and artificial intelligence for diabetes

The advent of the World Wide Web has changed the perspectives of groupware systems. The interest and deployment of Internet and intranet groupware solutions is growing rapidly, not just in academic circles but also in the commercial arena. The first generation of Web-based groupware tools has already started to emerge, and leading groupware vendors are urgently adapting their products for compatibility and integration with Web technologies. The focus of Groupware and the World Wide Web is to explore the potential for Web-based groupware. This book includes an analysis of the key characteristics of the Web, presenting reasons for its success, and describes developments of a diverse range of Web-based groupware systems. An emphasis on the technical obstacles and challenges is implemented by more analytical discussions and perspectives, including that of Information Technology managers looking to deploy groupware solutions within their organizations. Written by experts from different backgrounds - academic and commercial, technical and organizational - this book provides a unique overview of and insight into current issues and future possibilities concerning extension of the World Wide Web for group working.

An overview of African popular theatre, its history and contemporary formsIn this survey of theatre forms in sub-Saharan Africa from pre-colonial times to the present day, popular theatre is interpreted widely to include not only conventional drama, but such non-literary forms of performance as dance, mime, dramatised story-telling, masquerades, improvised urban vaudeville theatre, and the theatre of resistance and social action. The book also considers theatre embedded in the modern media of film, radio and television.Kenya: EAEP

This book will contain lectures given by four eminent speakers at the Recent Advances in Operator Theory and Operator Algebras conference held at the Indian Statistical Institute, Bangalore, India in 2014. The main aim of this book is to bring together various results in one place with cogent introduction and references for further study.

Citizenship through Secondary History reveals the potential of history to engage with citizenship education and includes:a review of the links between citizenship education and the teaching and learning of historyan analysis of how citizenship education is characterised, raising key issues about what could and should be achieveda critique of the discipline and the pitfalls to avoid in teaching citizenship through historycase studies offering practical teaching suggestions.History teaching is at the vanguard of citizenship education - the past is the springboard from which citizens learn to think and act. This book offers positive and direct ways to get involved in the thinking that must underpin any worthwhile citizenship education, for all professional teachers, student teachers in history, policy-makers, heads of department and principals.

Published in 1994. Integrating cross-curricular themes into the curriculum has emerged as a major challenge for all schools. What is their relevance to the specialist subject teacher? How can the hard-pressed teacher ensure their coverage through the statutory programmes of study and statements of attainment? How does a school ensure that each pupil's experience makes sense – across the curriculum, at any one time, and in the course of time? How can a school link with partners in the local community to enhance cross-curricular work? This challenge remains as National Curriculum content and procedures are streamlined. Primary and secondary school teachers will find here a book filled with practical suggestions from a wide range of subject-specialist viewpoints. These highlight opportunities for developing economic and industrial understanding (EIU) and economic awareness through work in the other cross-curricular areas, through the National Curriculum core and foundation subjects and through other areas of study. Whatever the shape of the National Curriculum in years to come, this book and its companion volumes provide – for heads and deputies, teachers engaged in curriculum coordination and delivery, school inspectors, advisers, initial teacher trainers, INSET providers and those in the community – a wealth of ideas to embed cross-curricular issues into the whole school and its curriculum.

Published in 1994. Integrating cross-curricular themes into the curriculum has emerged as a major challenge for all schools. What is their relevance to the specialist subject teacher? How can the hard-pressed teacher ensure their coverage through the statutory programmes of study and statements of attainment? How does a school ensure that each pupil's experience makes sense – across the curriculum, at any one time, and in the course of time? How can a school link with partners in the local community to enhance cross-curricular work? This challenge remains as National Curriculum content and procedures are streamlined. Primary and secondary school teachers will find here a book filled with practical suggestions from a wide range of subject-specialist viewpoints. These highlight opportunities for developing economic and industrial understanding (EIU) and economic awareness through work in the other cross-curricular areas, through the National Curriculum core and foundation subjects and through other areas of study. Whatever the shape of the National Curriculum in years to come, this book and its companion volumes provide – for heads and deputies, teachers engaged in curriculum coordination and delivery, school inspectors, advisers, initial teacher trainers, INSET providers and those in the community – a wealth of ideas to embed cross-curricular issues into the whole school and its curriculum.

One trait that defines great technologists is their ability to make their tools work for them by adapting the tools to their unique styles and needs. This book will help you do just that by using the shell. Investing a few hours in learning the command line techniques in Effective Shell will have a huge impact on your productivity. It will also make your work more fun. The shell's simple text-based interface lets you maintain a state of creative flow, free from the distractions of a graphical environment. This isn't a book on shell scripting or Linux administration. Each chapter presents a stand-alone set of techniques to help you work more efficiently, understand your system better, and tailor your environment to your individual workflow. This book doesn't ask you to totally change the way you work or drop your current tooling. Instead, it brings together a set of skills that you can add to your toolkit and incorporate as you like. The author focuses on the essentials that allow you to immediately apply the new skill rather than describing every possible feature. The goal is for you to be able to pick up the book, read a chapter over coffee, and try out what you've learned right away.

If we could know in 2020 what we will know in 2025 (only five foreseeable years into the future), how would we change our attitudes, actions, and the way in which we practice law, the services we offer, the clients we target, and the ways in which we choose to deliver our services? Indeed - if we could have known a year ago the events of the first three months in 2020, what might we have done to prepare? The American writer and humorist, Mark Twain, advised: "When everybody is out digging for gold, the business to be in is selling shovels!" So, what foreseeable trend may represent the figurative "shovel" that every client will need tomorrow?

This book provides an overview of Data Monitoring Committees(DMC) - what was done in the past, what is currently being done, and thoughts on improvements for the future. Previous works focused primarily on large cardiovascular studies (where DMCs originated more than 30 years ago) but updated references are needed that discuss smaller, more flexible studies in areas such as oncology. The authors have attended ~800 DMC meetings from ~200 distinct studies across all areas of clinical studies (oncology, rheumatology, rare diseases, cardiology, immunology, etc.) This wide range of expertise will be used, as well as the expertise that comes from working with virtually every large biotechnology and pharmaceutical company and CRO for DMC work. The reader of the book will know when DMCs are needed or helpful, how to form the DMC, how to work with external CROs and with sponsor teams and the DMC to create needed DMC outputs, how the DMC meetings are conducted, and - especially for DMC members - what are considerations within the Closed Session to review safety/efficacy outputs to assess risk/benefit to make appropriate recommendations that protect the patient safety and trial integrity.This is a practical hands-on book on how to decide if a DMC is necessary, how to form the DMC, how to expertly create the necessary materials for the DMC and have smooth running DMC meetings. There is no specialized training in school about how DMCs work - frequently people may have been in industry for many years without ever needing to work with a DMC. This book is the helpful reference for those new to these DMCs. The DMC work is critical to be correctly implemented as the impact of DMC activity on safeguarding the trial is so important.This book provides the following:Provides thorough instructions on the steps needed to form and implement a Data Monitoring Committee for clinical trial evaluation;Includes practical and hands-on information on DMC implementation;Discusses a wide range of clinical trial – by phase and therapeutic area.

This book provides an overview of Data Monitoring Committees(DMC) - what was done in the past, what is currently being done, and thoughts on improvements for the future. Previous works focused primarily on large cardiovascular studies (where DMCs originated more than 30 years ago) but updated references are needed that discuss smaller, more flexible studies in areas such as oncology. The authors have attended ~800 DMC meetings from ~200 distinct studies across all areas of clinical studies (oncology, rheumatology, rare diseases, cardiology, immunology, etc.) This wide range of expertise will be used, as well as the expertise that comes from working with virtually every large biotechnology and pharmaceutical company and CRO for DMC work. The reader of the book will know when DMCs are needed or helpful, how to form the DMC, how to work with external CROs and with sponsor teams and the DMC to create needed DMC outputs, how the DMC meetings are conducted, and - especially for DMC members - what are considerations within the Closed Session to review safety/efficacy outputs to assess risk/benefit to make appropriate recommendations that protect the patient safety and trial integrity.This is a practical hands-on book on how to decide if a DMC is necessary, how to form the DMC, how to expertly create the necessary materials for the DMC and have smooth running DMC meetings. There is no specialized training in school about how DMCs work - frequently people may have been in industry for many years without ever needing to work with a DMC. This book is the helpful reference for those new to these DMCs. The DMC work is critical to be correctly implemented as the impact of DMC activity on safeguarding the trial is so important.This book provides the following:Provides thorough instructions on the steps needed to form and implement a Data Monitoring Committee for clinical trial evaluation;Includes practical and hands-on information on DMC implementation;Discusses a wide range of clinical trial – by phase and therapeutic area.

This book is about the manipulation of the immune system as a therapeutic approach to gastrointestinal cancer and its clinical applications, exploring therapeutic approaches which might be taken under the broad banner of immunotherapy.Starting by introducing concepts of modern immunology, the clinical applications of immunotherapy are then discussed. The reader will learn about the three broad classes of immune therapeutic agents: cell-based treatment; antibody therapy; cytokine application and the key effector cells and mechanisms which might cause tumour rejection.  The reverse side of this equation, the genetic and molecular mechanisms which the tumour can use to escape immune control and regulation, is also discussed.  Through reviewing the most up-to-date evidence, this volume provides an overview of the important scientific lessons learned from past failure of immunotherapeutics in the clinic and highlights more positive recent data, coupled to practical guidelines for clinical usage.Written by a team of worldwide experts, this is an indispensable guide for medical oncologists, surgical oncologists, radiation therapists, pharmacists, oncology nurse specialists.