Debmalya Barh – författare

Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care.

Covers various aspects of biotechnology and bio-engineering using omics technologies Focuses on the latest developments in the field, including biofuel technologies Provides key insights into omics approaches in personalized and precision medicine Provides a complete picture on how one can utilize omics data in molecular biology, biotechnology and human health care

Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine.

Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development.

The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences.

Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health.

This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.

Covers not only the technological aspects, but also the diverse applications of single cell omics in the biomedical field Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis Written by experts across the world, bringing different points-of-view and case studies to give a comprehensive overview on the topic

Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 2 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care.

Covers various aspects of biotechnology and bio-engineering using omics technologies Focuses on the latest developments in the field, including biofuel technologies Provides key insights into omics approaches in personalized and precision medicine Provides a complete picture on how one can utilize omics data in molecular biology, biotechnology and human health care

Sports, Exercise, and Nutritional Genomics: Current Status and Future Directions is the first reference volume to offer a holistic examination of omics-driven advances across different aspects of exercise and sports physiology, biochemistry, sports medicine, psychology, anthropology, and sports nutrition; and highlighting the opportunities towards advance personalized training and athlete health management. More than 70 international experts from 14 countries have discussed key exercise and sport-related themes through the prism of genomics, epigenomics, transcriptomics, proteomics, metabolomics, telomere biology, talent in sport, individual differences in response to regular physical activity, that in the future may empower coaches, sports physicians, fitness experts, genetic counselors, and translational scientists to employ various omics data and approaches in improving health and physical performance of people participating in sports and exercise activities.

Contributors address current knowledge of genetic influence on athletic performance, individual responses to exercise training, as well as the genetics of musculoskeletal phenotypes, exercise-related injuries, flexibility, and neurodegenerative disorders in athletes.

Finally, performance-related and psychological traits associated with epigenetic, transcriptomic and metagenomic biomarkers are also considered, along with nutritional and pharmacogenomic aids in sports medicine and personalized nutrition.

Effectively synthesizes key themes across molecular aspects of exercise and sports sciences Provides a knowledge base for future translation of omics solutions to talent identification, individualized training, and nutrition Features contributions from international experts (researchers and clinicians) in the subject area

Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries is a comprehensive reference for animal biotechnologists, veterinary clinicians, fishery scientists, and anyone who needs to understand the latest advances in the field of next generation sequencing and genomic editing in animals and fish. This essential reference provides information on genomics and the advanced technologies used to enhance the production and management of farm and pet animals, commercial and non-commercial birds, and aquatic animals used for food and research purposes. This resource will help the animal biotechnology research community understand the latest knowledge and trends in this field.

Presents biological applications of cattle, poultry, marine and animal pathogen genomics Discusses the relevance of biomarkers to improve farm animals and fishery Includes recent approaches in cloning and transgenic cattle, poultry and fish production

Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches,� brings the main concepts and current approaches on pan-genomics research; the second, "case studies in pan-genomics,� thoroughly discusses twelve case, and the last, "current approaches and future prospects in pan-multiomics�, encompasses the developments on omics studies to be applied on bacteria related studies.

This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health.

Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives Discusses current bioinformatics tools and strategies for exploiting pangenomics data Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability

Artificial Intelligence in Precision Health: From Concept to Applications provides a readily available resource to understand artificial intelligence and its real time applications in precision medicine in practice. Written by experts from different countries and with diverse background, the content encompasses accessible knowledge easily understandable for non-specialists in computer sciences. The book discusses topics such as cognitive computing and emotional intelligence, big data analysis, clinical decision support systems, deep learning, personal omics, digital health, predictive models, prediction of epidemics, drug discovery, precision nutrition and fitness. Additionally, there is a section dedicated to discuss and analyze AI products related to precision healthcare already available.

This book is a valuable source for clinicians, healthcare workers, and researchers from diverse areas of biomedical field who may or may not have computational background and want to learn more about the innovative field of artificial intelligence for precision health.

Provides computational approaches used in artificial intelligence easily understandable for non-computer specialists Gives know-how and real successful cases of artificial intelligence approaches in predictive models, modeling disease physiology, and public health surveillance Discusses the applicability of AI on multiple areas, such as drug discovery, clinical trials, radiology, surgery, patient care and clinical decision support

Single-cell Omics, Volume 2: Advances in Applications provides the latest single-cell omics applications in the field of biomedicine. The advent of omics technologies have enabled us to identify the differences between cell types and subpopulations at the level of the genome, proteome, transcriptome, epigenome, and in several other fields of omics. The book is divided into two sections: the first is dedicated to biomedical applications, such as cell diagnostics, non-invasive prenatal testing (NIPT), circulating tumor cells, breast cancer, gliomas, nervous systems and autoimmune disorders, and more. The second focuses on cell omics in plants, discussing micro algal and single cell omics, and more.

This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and several members of biomedical field interested in understanding more about single-cell omics and its potential for research and diagnosis.

Covers the diverse single cell omics applications in the biomedical field Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis Written by experts across the world, it brings different points-of-view and study cases to fully give a comprehensive overview of the topic

Biotechnology in Healthcare, Technologies and Innovations, Volume One presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Sections cover 3D printing, tissue engineering, synthetic biology, nano-biotechnology, omics, precision medicine, gene therapy, vaccine development, predictive healthcare, entrepreneurship, financing, business models, product development and marketing in the sector. This is a valuable source for biotechnologists, bioinformaticians, clinicians and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare. Presents the progress and innovations that biotechnology has accomplished in the field of healthcare Discusses the impact of healthcare biotechnology in global economics and business prospects Explains how biotechnology revolutionizes future healthcare approaches

Biotechnology in Healthcare presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Biotechnology has revolutionized healthcare in the last two decades by developing and introducing novel diagnostics, therapeutics, and preventive measures; whether it is noncommunicable or communicable disease, primary or secondary care, or public health, it has shown its immense potential to provide a solution to the healthcare providers, physicians, and allied health care professionals.The second volume, Applications and Initiatives, contains 19 chapters focused on the applications of biotechnology related to public healthcare, hospital management, oncology, neurodegenerative and infectious diseases, regenerative medicine, IVF, clinical trials, precision food, FMGCs, PPCPs, pharmaceuticals, and smart technologies to monitor pandemic. Further, this volume also presents government initiatives and entrepreneurship challenges in healthcare biotechnology sector.This is a valuable resource for students, biotechnologists, bioinformaticians, clinicians, and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare. Describes various applications of novel biotechnology approaches in healthcare Presents applications of biotechnology in primary and secondary healthcare and in public health Discusses government initiatives, challenges and opportunities, and entrepreneurship development in the area of healthcare biotechnology

The COVID-19 pandemic has affected the entire world in an unprecedented way since 2019. However, novel and innovative applications of various omics, computational, and smart technologies have helped manage the pandemic of the 21st century in a very effective manner. Omics approaches and technologies in COVID-19 presents up-to-date knowledge on omics, genetic engineering, mathematical and computational approaches, and advanced technologies in the diagnosis, prevention, monitoring, and management of COVID-19.

This book contains 26 chapters written by academic and industry experts from more than 15 countries. Split into three sections (Omics; Artificial Intelligence and Bioinformatics; and Smart and Emerging Technologies), it brings an overview of novel technologies under omics such as, genomic, metagenomic, pangenomic, metabolomics and proteomics in COVID-19. In addition, it discusses hostpathogen interactions and interactomics, management options, application of genetic engineering, mathematical modeling andsimulations, systems biology, and bioinformatics approaches in COVID-19 drug discovery and vaccine development.

This is a valuable resource for students, biotechnologists, bioinformaticians, virologists, clinicians, and pharmaceutical, biomedical, and healthcare industry people who want to understand the promising omics and other technologies used in combating COVID-19 from various aspects.

Provides novel technologies for rapid diagnostics, drug discovery, vaccine development, monitoring, prediction of future waves, etc. Describes various omics applications including genomics, metagenomics, epigenomics, nutrigenomics, transcriptomics,miRNAomics, proteomics, metabolomics, phenomics, multiomics, etc., in COVID-19 Presents applications of genetic engineering, CRISPR, artificial intelligence, mathematical and in silico modeling, systems biology,and other computational approaches in COVID-19 Discusses emerging, digital, and smart technologies for the monitoring and management of COVID-19�

The availability of human genome, large amount of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the era of clinical practice of "Precision Medicine". This book aims to provide a readily available resource on all the important developments achieved so far in the field of oncology. All recent developments have been explained along with epidemiology, technologies and approaches to manage the included diseases. Therefore, readers will get the up to date information on the next-generation approach in tackling all kinds of cancer.Key Features• Presents the latest trend of cancer management based on precision/predictive medicine approach• Reviews the latest and up to date literature in the field of Precision Medicine• Highlights the next generation approach in tackling malignant diseases• Discusses how a life-threatening disease like cancer can be managed with the help of Precision Medicine• Encapsulates a global prospective

Applied Molecular Biotechnology: The Next Generation of Genetic Engineering explains state-of-the-art advances in the rapidly developing area of molecular biotechnology, the technology of the new millennium. Comprised of chapters authored by leading experts in their respective fields, this authoritative reference text: Highlights the latest omics-based tools and approaches used in modern biotechnologyExplains how various molecular biology technologies can be used to develop transgenic plants and how those plants can meet growing food and plant-derived product demandsDiscusses chloroplast gene expression systems, mitochondrial omics, plant functional genomics, and whole-genome resequencing for crop improvementExplores plant–microbe and plant–insect interactions affecting plant protection and productivityCovers animal models, pharmacogenomics, human tissue banking, and the molecular diagnosis of diseases such as cervical cancer, obesity, and diabetesExamines the molecular aspects of viral diseases, production of industrial commodities using viral biotechnology, and biotechnological uses of magnetic nanoparticlesDescribes the use of biotechnology in the food, chemical, pharmaceutical, environmental conservation, and renewable energy sectorsApplied Molecular Biotechnology: The Next Generation of Genetic Engineering serves as a springboard for new discoveries in molecular biology and its applications. Thus, this book is an invaluable resource for students and researchers of molecular biotechnology.

Deep Learning Applications in Translational Bioinformatics, a new volume in the Advances in Ubiquitous Sensing Application for Healthcare series, offers a detailed overview of basic bioinformatics, deep learning, and various applications of deep learning in translational bioinformatics, including deep learning ensembles, deep learning in protein classification, detection of various diseases, prediction of antiviral peptides, identification of antibiotic resistance, computer aided drug design and drug formulation. This new volume helps researchers working in the field of machine learning and bioinformatics foster future research and development.

Addresses the practical application of deep learning algorithms to a wide range of bioinformatics challengesPresents integrative and multidisciplinary approaches to ubiquitous healthcareIncludes case studies to illustrate the concepts discussed

Probiogenomics and Probiomics: Concepts, Techniques, Applications, and Achievements is a pioneering reference book that marks a significant milestone in the emerging fields of probiogenomics and probiomics. As the first comprehensive resource in these disciplines, the book offers a detailed exploration of how genetic insights and omics technologies are revolutionizing our understanding of probiotics and their application in health and disease. Spanning three detailed sections, the book begins by grounding readers in the fundamental concepts of probiotics, including their roles in health enhancement and disease prevention. It progresses into a deep dive into advanced genomic and post-genomic technologies, revealing how these tools are used to dissect and harness the health-promoting capacities of probiotics. From the structure and function of probiotic genomes to the cutting-edge applications in synthetic biology and multi-omics, the book encapsulates the latest advancements and methodologies in the field. The final sections focus on the practical and clinical applications of these microbial marvels, discussing their impact on healthcare, biotechnology, and therapeutics. Whether it's developing new biotechnological products or enhancing therapeutic efficacy, this book covers a broad spectrum of applications, making it an invaluable resource for undergraduate and postgraduate students, researchers, clinicians, and industry professionals involved in drug and probiotics development. With contributions from over ten global experts, "Probiogenomics and Probiomics" not only educates but also inspires, providing a thorough understanding of modern probiogenomics and its potential to shape the future of personalized medicine and healthcare.Offers the first complete guide to probiogenomics and probiomics, providing foundational knowledge, advanced techniques, and the latest research outcomes in the rapidly evolving field of probioticsDetails state-of-the-art genomic and multi-omics approaches, from transcriptomics to metabolomics, showcasing their application in understanding and enhancing the functionality of probioticsHighlights the practical implementation of probiogenomic studies in developing new biotechnological products and enhancing healthcare therapies, making it invaluable for professionals in both academic and industry settingsIntegrates insights from genetics, microbiology, bioinformatics, and healthcare to foster a comprehensive understanding of how probiotics can be optimized for health promotion and therapeutic interventions

The COVID-19 pandemic has affected the entire world in an unprecedented way, and this book provides an overview of the historical facts as well as ongoing approaches to tackle the COVID-19 pandemic. Experts of the respective domains provide details on anti-SARS-CoV-2 drug strategies, including repurposing drugs used for other indications and the development of novel drugs looking at different approaches to target virus entry and replication. COVID-19 vaccine development based on inactivated and attenuated live virus, protein subunit and peptide-based vaccines and utilization of vaccine candidates based on viral vectors, DNA and RNA are presented for both preclinical studies and clinical trials. Key Features Explains the background of the COVID-19 pandemic, the current progress in the development of treatments and prevention of COVID-19 including future aspects of dealing with the pandemic Serves as a timely repository of knowledge on COVID-19 for researchers and medical professionals engaged in its management

The COVID-19 pandemic has affected the entire world in an unprecedented way, and this book provides an overview of the historical facts as well as ongoing approaches to tackle the COVID-19 pandemic. Experts of the respective domains provide details on anti-SARS-CoV-2 drug strategies, including repurposing drugs used for other indications and the development of novel drugs looking at different approaches to target virus entry and replication. COVID-19 vaccine development based on inactivated and attenuated live virus, protein subunit and peptide-based vaccines and utilization of vaccine candidates based on viral vectors, DNA and RNA are presented for both preclinical studies and clinical trials. Key Features Explains the background of the COVID-19 pandemic, the current progress in the development of treatments and prevention of COVID-19 including future aspects of dealing with the pandemic Serves as a timely repository of knowledge on COVID-19 for researchers and medical professionals engaged in its management

A reflection of the explosion of research and development in this field, OMICS: Biomedical Perspectives and Applications explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. A select editorial panel of experts discusses their cutting edge omics research and novel technologies, supplying a basic platform of methods and applications and a resource for enhanced cross-pollination in a multiomics approach to future endeavors in the fertile fields of omics research.After an introduction on the omics universe, the book presents modern omics and its applications in nanotechnology, genomics, proteomics, metagenomics, toxicogenomics, immunomics, nutrigenomics, diabetes, neurology, cardiology, and cancer to name just a few. The book begins with an overview of omics and omic technologies such as cellomics, glycomics, and lipidomics. It also discusses bioinformatics, demonstrating how it can be a tool in omics, and examines the various approaches of omics technology in toxicology research and applications in biomedical sciences.While there are a long list of omics books available, most focus narrowly on one area. Presenting a wide view of the current status of integrative omics, this resource contains complete coverage of omics in research and therapy, ranging from neuroscience to cardiology. It collates recent developments in the field into a state-of-the-art framework for this discipline.

With the advent of new technologies and acquired knowledge, the number of fields in omics and their applications in diverse areas are rapidly increasing in the postgenomics era. Such emerging fields—including pharmacogenomics, toxicogenomics, regulomics, spliceomics, metagenomics, and environomics—present budding solutions to combat global challenges in biomedicine, agriculture, and the environment. OMICS: Applications in Biomedical, Agricultural, and Environmental Sciences provides valuable insights into the applications of modern omics technologies to real-world problems in the life sciences. Filling a gap in the literature, it offers a broad, multidisciplinary view of current and emerging applications of omics in a single volume.Written by highly experienced active researchers, each chapter describes a particular area of omics and the associated technologies and applications. Topics covered include:Proteomics, epigenomics, and pharmacogenomicsToxicogenomics and the assessment of environmental pollutantsApplications of plant metabolomicsNutrigenomics and its therapeutic applicationsMicroalgal omics and omics approaches in biofuel production Next-generation sequencing and omics technology for transgenic plant analysisOmics approaches in crop improvement Engineering dark-operative chlorophyll synthesis Computational regulomicsOmics techniques for the analysis of RNA splicingNew fields, including metagenomics, glycomics, and miRNABreast cancer biomarkers for early detectionEnvironomics strategies for environmental sustainabilityThis timely book explores a wide range of omics application areas in the biomedical, agricultural, and environmental sciences. Throughout, it highlights working solutions as well as open problems and future challenges. Demonstrating the diversity of omics, it introduces readers to state-of-the-art developments and trends in omics-driven research.

Merging topical data from recently published review and research articles, as well as the knowledge and insight of industry experts, Omics Applications in Crop Science delves into plant science, and various technologies that use omics in agriculture. This book concentrates on crop breeding and environmental applications, and examines the applications of various omics technologies including genomics, transcriptomics, proteomics, metabolomics to important agronomic, horticultural, medicinal, plantation, fiber, forage, and bioenergy crops. It covers the application of omics technologies in several important crops, including cereal, and pulse. It explores the brassica species, drought tolerance in rice, and genetic engineering of the potato. The book discusses temperate fruits; and omics of medicinal plants, the metabolomics of Catharanthus roseus and how the medicinally important alkaloids of the plant are produced, as well as the omics of another important medicinal plant, Withania somnifera. It examines floriculture, the omics advances in tea, and omics strategies in improving the fiber qualities of cotton. It provides omics-related information on forest trees and forage crops, and offers a detailed account on how omics technologies are applicable in molecular farming, along with associated issues such as commercial aspects of molecular farming, clinical trials of plant-produced pharmaceuticals, regulatory issues and intellectual property rights. Written as a resource for plant biologists, plant breeders, agriculture scientists, researchers and college students studying various fields in agriculture, and the agri industries, OMICS Applications in Crop Science compiles the latest research in this essential field of modern crop and plant science utilizing various omics technologies and their applications in a number of important crops/plants from agronomy, pomology, olericulture, floriculture, medicinal plants, plantation and energy crops, agro-forestry, and more.

Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer markers that are under development or currently in use. It deals with a majority of commonly prevalent cancers and can help anyone working in the health-care industry to recommend or develop early diagnostics, at-risk tests, and prognostic biomarkers for various cancers. It explores the practice of determining biomarkers by their characteristics and relative methodologies, and presents the most recent data as well as a number of current and upcoming early diagnostic noninvasive molecular markers for many common cancers. It also considers the sensitivity and specificity of markers, biomarker market, test providers, and patent information. Approximately 30-35 Cancer Specific Noninvasive Molecular Diagnostic Markers in a Single VolumeThe book details the general and technical aspects of noninvasive cancer markers. It covers imaging, cutting-edge molecular technologies for biomarker development, and noninvasive or minimally invasive sources of molecular markers, as well as quality control and ethical issues in cancer biomarker discovery. It also provides a detailed account of brain, head and neck, and oral cancer markers, and provides information on a number of gastrointestinal cancers, lung cancer, and mesothelioma markers. Emphasizes the Importance of Volatile Markers in Early Cancer DiagnosisPresents noninvasive early molecular markers in urological cancersDescribes gynecological and endocrine cancer markers Details noninvasive markers of breast, ovarian, cervical, and thyroid cancers Addresses hematological malignancies Contains information on noninvasive molecular markers in myelodysplastic syndromes, acute myeloid leukemia, Hodgkin’s lymphoma, and multiple myelomaProvides comprehensive information on diagnostic and prognostic biomarkers in cutaneous melanomaThis text considers molecular technologies for biomarker development, noninvasive or minimally invasive sources of molecular markers, and quality control and ethical issues in cancer biomarker discovery.

Early detection is critical for any given cancer. With the advent of the latest omics technologies, molecular markers in combination with conventional diagnostic and screening methods are emerging as next-generation early diagnostic and prognostic strategies that can allow early-stage diagnosis, resulting in more effective treatment and patient care and, in turn, an increased rate of survival. A ready-made resource, Noninvasive Molecular Markers in Gynecologic Cancers not only provides information on noninvasive molecular diagnostic biomarkers, it includes coverage of the epidemiology, clinical features, conventional diagnosis, treatment, and prognosis for these cancers.With contributions from leading international experts, the book presents a compact but comprehensive overview of gynecologic cancer. Each of the five main gynecologic cancers—ovarian, cervical, uterine, vaginal, and vulvar—have unique signs and symptoms, risk factors, and molecular profile, and therefore requires different prevention strategies. This book describes the different features of each gynecologic cancer in separate chapters covering general information, epidemiology, clinical features, and biomarkers. The book also covers breast cancer and, although rare, fallopian tube cancer, to make it a complete resource. In cancer treatment, non-invasive diagnosis can avoid complications of biopsy and other unfavorable impacts on patients’ health. DNA, methylation, SNPs, miRNA, mRNA, protein, autoantibodies, metabolite, and omics-based markers from remote media such as blood, plasma, and urine are emerging as noninvasive molecular markers with high specificity and sensitivity towards many cancers. This book classifies the available molecular tumor markers according to their principal characteristics and relative methodologies. It covers markers that not only provide early detection and better treatment options, but are emerging as next-generation personalized diagnostics and targets or therapeutics for personalized cancer treatment.

A reflection of the explosion of research and development in this field, OMICS: Biomedical Perspectives and Applications explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. A select editorial panel of experts discusses their cutting edge omics research and novel technologies, supplying a basic platform of methods and applications and a resource for enhanced cross-pollination in a multiomics approach to future endeavors in the fertile fields of omics research.After an introduction on the omics universe, the book presents modern omics and its applications in nanotechnology, genomics, proteomics, metagenomics, toxicogenomics, immunomics, nutrigenomics, diabetes, neurology, cardiology, and cancer to name just a few. The book begins with an overview of omics and omic technologies such as cellomics, glycomics, and lipidomics. It also discusses bioinformatics, demonstrating how it can be a tool in omics, and examines the various approaches of omics technology in toxicology research and applications in biomedical sciences.While there are a long list of omics books available, most focus narrowly on one area. Presenting a wide view of the current status of integrative omics, this resource contains complete coverage of omics in research and therapy, ranging from neuroscience to cardiology. It collates recent developments in the field into a state-of-the-art framework for this discipline.

With the advent of new technologies and acquired knowledge, the number of fields in omics and their applications in diverse areas are rapidly increasing in the postgenomics era. Such emerging fields—including pharmacogenomics, toxicogenomics, regulomics, spliceomics, metagenomics, and environomics—present budding solutions to combat global challenges in biomedicine, agriculture, and the environment. OMICS: Applications in Biomedical, Agricultural, and Environmental Sciences provides valuable insights into the applications of modern omics technologies to real-world problems in the life sciences. Filling a gap in the literature, it offers a broad, multidisciplinary view of current and emerging applications of omics in a single volume.Written by highly experienced active researchers, each chapter describes a particular area of omics and the associated technologies and applications. Topics covered include:Proteomics, epigenomics, and pharmacogenomicsToxicogenomics and the assessment of environmental pollutantsApplications of plant metabolomicsNutrigenomics and its therapeutic applicationsMicroalgal omics and omics approaches in biofuel production Next-generation sequencing and omics technology for transgenic plant analysisOmics approaches in crop improvement Engineering dark-operative chlorophyll synthesis Computational regulomicsOmics techniques for the analysis of RNA splicingNew fields, including metagenomics, glycomics, and miRNABreast cancer biomarkers for early detectionEnvironomics strategies for environmental sustainabilityThis timely book explores a wide range of omics application areas in the biomedical, agricultural, and environmental sciences. Throughout, it highlights working solutions as well as open problems and future challenges. Demonstrating the diversity of omics, it introduces readers to state-of-the-art developments and trends in omics-driven research.

Early detection is critical for any given cancer. With the advent of the latest omics technologies, molecular markers in combination with conventional diagnostic and screening methods are emerging as next-generation early diagnostic and prognostic strategies that can allow early-stage diagnosis, resulting in more effective treatment and patient care and, in turn, an increased rate of survival. A ready-made resource, Noninvasive Molecular Markers in Gynecologic Cancers not only provides information on noninvasive molecular diagnostic biomarkers, it includes coverage of the epidemiology, clinical features, conventional diagnosis, treatment, and prognosis for these cancers.With contributions from leading international experts, the book presents a compact but comprehensive overview of gynecologic cancer. Each of the five main gynecologic cancers—ovarian, cervical, uterine, vaginal, and vulvar—have unique signs and symptoms, risk factors, and molecular profile, and therefore requires different prevention strategies. This book describes the different features of each gynecologic cancer in separate chapters covering general information, epidemiology, clinical features, and biomarkers. The book also covers breast cancer and, although rare, fallopian tube cancer, to make it a complete resource. In cancer treatment, non-invasive diagnosis can avoid complications of biopsy and other unfavorable impacts on patients’ health. DNA, methylation, SNPs, miRNA, mRNA, protein, autoantibodies, metabolite, and omics-based markers from remote media such as blood, plasma, and urine are emerging as noninvasive molecular markers with high specificity and sensitivity towards many cancers. This book classifies the available molecular tumor markers according to their principal characteristics and relative methodologies. It covers markers that not only provide early detection and better treatment options, but are emerging as next-generation personalized diagnostics and targets or therapeutics for personalized cancer treatment.

Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer markers that are under development or currently in use. It deals with a majority of commonly prevalent cancers and can help anyone working in the health-care industry to recommend or develop early diagnostics, at-risk tests, and prognostic biomarkers for various cancers. It explores the practice of determining biomarkers by their characteristics and relative methodologies, and presents the most recent data as well as a number of current and upcoming early diagnostic noninvasive molecular markers for many common cancers. It also considers the sensitivity and specificity of markers, biomarker market, test providers, and patent information. Approximately 30-35 Cancer Specific Noninvasive Molecular Diagnostic Markers in a Single VolumeThe book details the general and technical aspects of noninvasive cancer markers. It covers imaging, cutting-edge molecular technologies for biomarker development, and noninvasive or minimally invasive sources of molecular markers, as well as quality control and ethical issues in cancer biomarker discovery. It also provides a detailed account of brain, head and neck, and oral cancer markers, and provides information on a number of gastrointestinal cancers, lung cancer, and mesothelioma markers. Emphasizes the Importance of Volatile Markers in Early Cancer DiagnosisPresents noninvasive early molecular markers in urological cancersDescribes gynecological and endocrine cancer markers Details noninvasive markers of breast, ovarian, cervical, and thyroid cancers Addresses hematological malignancies Contains information on noninvasive molecular markers in myelodysplastic syndromes, acute myeloid leukemia, Hodgkin’s lymphoma, and multiple myelomaProvides comprehensive information on diagnostic and prognostic biomarkers in cutaneous melanomaThis text considers molecular technologies for biomarker development, noninvasive or minimally invasive sources of molecular markers, and quality control and ethical issues in cancer biomarker discovery.

Merging topical data from recently published review and research articles, as well as the knowledge and insight of industry experts, Omics Applications in Crop Science delves into plant science, and various technologies that use omics in agriculture. This book concentrates on crop breeding and environmental applications, and examines the applications of various omics technologies including genomics, transcriptomics, proteomics, metabolomics to important agronomic, horticultural, medicinal, plantation, fiber, forage, and bioenergy crops. It covers the application of omics technologies in several important crops, including cereal, and pulse. It explores the brassica species, drought tolerance in rice, and genetic engineering of the potato. The book discusses temperate fruits; and omics of medicinal plants, the metabolomics of Catharanthus roseus and how the medicinally important alkaloids of the plant are produced, as well as the omics of another important medicinal plant, Withania somnifera. It examines floriculture, the omics advances in tea, and omics strategies in improving the fiber qualities of cotton. It provides omics-related information on forest trees and forage crops, and offers a detailed account on how omics technologies are applicable in molecular farming, along with associated issues such as commercial aspects of molecular farming, clinical trials of plant-produced pharmaceuticals, regulatory issues and intellectual property rights. Written as a resource for plant biologists, plant breeders, agriculture scientists, researchers and college students studying various fields in agriculture, and the agri industries, OMICS Applications in Crop Science compiles the latest research in this essential field of modern crop and plant science utilizing various omics technologies and their applications in a number of important crops/plants from agronomy, pomology, olericulture, floriculture, medicinal plants, plantation and energy crops, agro-forestry, and more.

Applied Molecular Biotechnology: The Next Generation of Genetic Engineering explains state-of-the-art advances in the rapidly developing area of molecular biotechnology, the technology of the new millennium. Comprised of chapters authored by leading experts in their respective fields, this authoritative reference text: Highlights the latest omics-based tools and approaches used in modern biotechnologyExplains how various molecular biology technologies can be used to develop transgenic plants and how those plants can meet growing food and plant-derived product demandsDiscusses chloroplast gene expression systems, mitochondrial omics, plant functional genomics, and whole-genome resequencing for crop improvementExplores plant–microbe and plant–insect interactions affecting plant protection and productivityCovers animal models, pharmacogenomics, human tissue banking, and the molecular diagnosis of diseases such as cervical cancer, obesity, and diabetesExamines the molecular aspects of viral diseases, production of industrial commodities using viral biotechnology, and biotechnological uses of magnetic nanoparticlesDescribes the use of biotechnology in the food, chemical, pharmaceutical, environmental conservation, and renewable energy sectorsApplied Molecular Biotechnology: The Next Generation of Genetic Engineering serves as a springboard for new discoveries in molecular biology and its applications. Thus, this book is an invaluable resource for students and researchers of molecular biotechnology.