Derek J. Chadwick – författare
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88 produkter
Percept, Decision, Action
Bridging the Gaps
Av Derek J. Chadwick, Matthew Diamond m. fl.
Inbunden, 2006
2327 kr
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Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception, comparing percepts to stored models (short-term and long-term memory), decision-making and planning of actions were treated by most neuroscientists …
Epithelial Anion Transport in Health and Disease
The Role of the SLC26 Transporters Family
Av Derek J. Chadwick, Jamie A. Goode
Inbunden, 2006
2327 kr
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Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family. It is now clear …
hERG Cardiac Potassium Channel
Structure, Function and Long QT Syndrome
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2005
2735 kr
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This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding. It features regulatory authority perspectives on preferred preclinical test systems and …
Innate Immunity to Pulmonary Infection
Av Derek J. Chadwick, Jamie A. Goode
Inbunden, 2007
2327 kr
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Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. Innate Immunity to Pulmonary Infection: Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, …
Sepsis
New Insights, New Therapies
Av Derek J. Chadwick, Jamie A. Goode
Inbunden, 2007
2371 kr
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Sepsis: New Insights, New Therapies brings together contributions from an international group of experts in diverse fields to consider how the various pathways implicated in early and late sepsis interact, with a particular emphasis on novel concepts and potential new therapeutic approaches. Topics …
Epithelial Anion Transport in Health and Disease
The Role of the SLC26 Transporters Family
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2006
2735 kr
Lägg i varukorg
Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family. It is now clear …
Mast Cells and Basophils
Development, Activation and Roles in Allergic / Autoimmune Disease
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2006
2735 kr
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The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scientific findings in the context of therapeutic …
Purinergic Signalling in Neuron-Glia Interactions
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2006
2735 kr
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ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry of ATP and its derivatives is complex, and the multiple membrane receptors that it activates are …
Percept, Decision, Action
Bridging the Gaps
Av Jamie A. Goode, Matthew Diamond m. fl.
E-bok, 2006
2735 kr
Lägg i varukorg
Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception, comparing percepts to stored models (short-term and long-term memory), decision-making and planning of actions were treated by most neuroscientists …
Signalling Pathways in Acute Oxygen Sensing
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2006
2656 kr
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Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are all subjects of controversy. This book evaluates the various mediators that have been proposed, …
Innate Immunity to Pulmonary Infection
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2007
2735 kr
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Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. Innate Immunity to Pulmonary Infection: Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, …
Mitochondrial Biology
New Perspectives
Av Derek J. Chadwick, Jamie A. Goode
Inbunden, 2007
2327 kr
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With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of the current state-of-the-art in mitochondrial research. The book opens with the regulation of mitochondrial replication and biogenesis and reviews …
Inflammatory Bowel Disease
Crossroads of Microbes, Epithelium and Immune Systems
Av Derek J. Chadwick, Jamie A. Goode
Inbunden, 2004
2369 kr
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Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the exact cause of IBD remains undetermined, the condition appears to be related to a combination of …
Inflammatory Bowel Disease
Crossroads of Microbes, Epithelium and Immune Systems
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2005
2735 kr
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Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the exact cause of IBD remains undetermined, the condition appears to be related to a combination of …
Molecular Clocks and Light Signalling
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2004
2598 kr
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The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary feature of these biological clocks is their ability to entrain to environmental stimuli. The dominant stimulus comes from environmental light cues, …
Nuclear Organization in Development and Disease
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2006
2598 kr
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This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a better understanding of the cellular and molecular basis of these diseases. Topics include: How nuclear structure and location within a nucleus affect …
Vascular Development
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2007
2725 kr
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The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In …
Acetaldehyde-Related Pathology
Bridging the Trans-Disciplinary Divide
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2007
2785 kr
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Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in cigarette smoke and other pollutants and derived from ingested alcohol, amongst other sources. In the body, acetaldehyde affects several tissues, …
IgE, Mast Cells and the Allergic Response
Av Julie Whelan, David Evered m. fl.
E-bok, 2008
1745 kr
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Reviews recent basic research into IgE, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses new methods of treatment. This symposium is unique in the IgE field for its breadth of coverage and interdisciplinary nature, and it shows the …
Human Genetic Information
Science, Law and Ethics
Av Julie Whelan, Gregory R. Bock m. fl.
E-bok, 2008
1745 kr
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As part of a continuing effort to tackle issues of major social concern, this 280th conference of internationally recognized experts from the fields of molecular biology, medicine, philosophy, theology, and the law looks into the scientific, legal, ethical, social, and economic issues confronting …
Steroids and Neuronal Activity
Av Kate Widdows, Derek J. Chadwick
E-bok, 2008
1694 kr
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Classical studies of steroid hormones are concerned with their regulation of protein synthesis via the modulation of genomic transcription. But many of the actions of these hormones occur too rapidly to be explained in this manner, particularly their effects on the central nervous system. This text …
Bioactive Compounds from Plants
Av Joan Marsh, Derek J. Chadwick
E-bok, 2008
1727 kr
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Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to environmental factors. The isolation and characterization of plant products, the identification of their role in the plant, and ways of synthesizing …
Host-Guest Molecular Interactions
From Chemistry to Biology
Av Kate Widdows, Derek J. Chadwick
E-bok, 2008
1694 kr
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Composed of contributions from experts in the chemical and biological sciences, it explores host-guest molecular interactions leading to the formation of molecular assemblies containing two or more species. Exciting applications are emerging in this field and it is expected that improved …
Catalytic Antibodies
Av Joan Marsh, Derek J. Chadwick
E-bok, 2008
1694 kr
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Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antibodies can possess catalytic activity is a recent advance with profound ramifications for chemistry. …
Protein Conformation
Av Kate Widdows, Derek J. Chadwick
E-bok, 2008
1745 kr
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How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry. Leading experts in the fields of NMR spectroscopy, X-ray crystallography, protein engineering and molecular modeling offer provocative insights into current views on the …
Exploring Brain Functional Anatomy with Positron Tomography
Av Julie Whelan, Derek J. Chadwick
E-bok, 2008
1745 kr
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Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET technology. Includes chapters on somatosensory, motor and visual systems, and higher-order processes such as attention, memory, learning, intention …
Postimplantation Development in the Mouse
Av Joan Marsh, Derek J. Chadwick
E-bok, 2008
1694 kr
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Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning stages of primitive streak formation. Discusses patterns of gene expression during the development of such tissues as the limb bud, skeletal, muscle and …
Functional Anatomy of the Neuroendocrine Hypothalamus
Av Joan Marsh, Derek J. Chadwick
E-bok, 2008
1745 kr
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Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into the function of the hypothalamus.
Aluminium in Biology and Medicine
Av Julie Whelan, Derek J. Chadwick
E-bok, 2008
1745 kr
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Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known to damage animals and plants via acid rain. Examines the chemistry and biology of aluminum compounds focusing on the evidence for and against …
Secondary Metabolites
Their Function and Evolution
Av Julie Whelan, Derek J. Chadwick
E-bok, 2008
1694 kr
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A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms. Examines the traditional context of secondary metabolites as natural products having no obvious part to play in the producing organism''s life …