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129 produkter
Molecular Mechanisms Influencing Aggressive Behaviours
Av Gregory R. Bock, Jamie A. Goode
Inbunden, 2005
2211 kr
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This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current experimental issues in the study of aggression in …
Molecular Mechanisms Influencing Aggressive Behaviours
Av Jamie A. Goode, Gregory R. Bock
E-bok, 2006
2656 kr
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This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current experimental issues in the study of aggression in …
Percept, Decision, Action
Bridging the Gaps
Av Derek J. Chadwick, Matthew Diamond m. fl.
Inbunden, 2006
2327 kr
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Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception, comparing percepts to stored models (short-term and long-term memory), decision-making and planning of actions were treated by most neuroscientists …
Heart Failure
Molecules, Mechanisms and Therapeutic Targets
Av Gregory R. Bock, Jamie A. Goode
Inbunden, 2006
2400 kr
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Heart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associated with heart failure and cardiac enlargement. Over recent years, dramatic progress has been made in unravelling …
Epithelial Anion Transport in Health and Disease
The Role of the SLC26 Transporters Family
Av Derek J. Chadwick, Jamie A. Goode
Inbunden, 2006
2327 kr
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Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family. It is now clear …
Signalling Networks in Cell Shape and Motility
Av Jamie A. Goode, Gregory R. Bock
E-bok, 2005
2598 kr
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This book features contributions from experts in cell biology, genetics, neurobiology, immunology and structural biology. The unifying element is that they all study processes of cell shape change and motility. Several key questions in this field of research are discussed: What are the organising …
Genetics of Autoimmunity
Av Gregory R. Bock, Jamie A. Goode
Inbunden, 2005
2369 kr
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This title provides an extremely helpful analysis of genes that may be associated with autoimmunity, and answers questions such as how these genes can be identified, and how the functions of the gene products can be elucidated. Incorporating data on disease-associated chromosomal loci that has been …
Genetics of Autoimmunity
Av Jamie A. Goode, Gregory R. Bock
E-bok, 2005
2735 kr
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This title provides an extremely helpful analysis of genes that may be associated with autoimmunity, and answers questions such as how these genes can be identified, and how the functions of the gene products can be elucidated. Incorporating data on disease-associated chromosomal loci that has been …
hERG Cardiac Potassium Channel
Structure, Function and Long QT Syndrome
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2005
2735 kr
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This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding. It features regulatory authority perspectives on preferred preclinical test systems and …
Innate Immunity to Pulmonary Infection
Av Derek J. Chadwick, Jamie A. Goode
Inbunden, 2007
2327 kr
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Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. Innate Immunity to Pulmonary Infection: Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, …
Sepsis
New Insights, New Therapies
Av Derek J. Chadwick, Jamie A. Goode
Inbunden, 2007
2371 kr
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Sepsis: New Insights, New Therapies brings together contributions from an international group of experts in diverse fields to consider how the various pathways implicated in early and late sepsis interact, with a particular emphasis on novel concepts and potential new therapeutic approaches. Topics …
Understanding Nicotine and Tobacco Addiction
Av Jamie A. Goode, Gregory R. Bock
E-bok, 2006
2785 kr
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Cigarette smoking is estimated to lead to 4.9 million premature deaths per year worldwide. This is predicted to rise to 10 million by 2020. In western countries it kills half of all smokers who fail to stop. The prevailing model for tobacco addiction is that nicotine from cigarettes rewards smoking …
Heart Failure
Molecules, Mechanisms and Therapeutic Targets
Av Jamie A. Goode, Gregory R. Bock
E-bok, 2006
2735 kr
Lägg i varukorg
Heart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associated with heart failure and cardiac enlargement. Over recent years, dramatic progress has been made in unravelling …
Epithelial Anion Transport in Health and Disease
The Role of the SLC26 Transporters Family
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2006
2735 kr
Lägg i varukorg
Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family. It is now clear …
Mast Cells and Basophils
Development, Activation and Roles in Allergic / Autoimmune Disease
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2006
2735 kr
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The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scientific findings in the context of therapeutic …
Empathy and Fairness
Av Jamie A. Goode, Gregory R. Bock
E-bok, 2007
2705 kr
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Empathy is the process that allows us to share the feelings and emotions of others, in the absence of any direct emotional stimulation to the self. Humans can feel empathy for other people in a wide array of contexts: for basic emotions and sensation such as anger, fear, sadness, joy, pain and lust …
Purinergic Signalling in Neuron-Glia Interactions
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2006
2735 kr
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ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry of ATP and its derivatives is complex, and the multiple membrane receptors that it activates are …
Percept, Decision, Action
Bridging the Gaps
Av Jamie A. Goode, Matthew Diamond m. fl.
E-bok, 2006
2735 kr
Lägg i varukorg
Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception, comparing percepts to stored models (short-term and long-term memory), decision-making and planning of actions were treated by most neuroscientists …
Signalling Pathways in Acute Oxygen Sensing
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2006
2656 kr
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Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are all subjects of controversy. This book evaluates the various mediators that have been proposed, …
Innate Immunity to Pulmonary Infection
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2007
2735 kr
Lägg i varukorg
Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. Innate Immunity to Pulmonary Infection: Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, …
Fatty Acid and Lipotoxicity in Obesity and Diabetes
Av Gregory R. Bock, Jamie A. Goode
Inbunden, 2008
2444 kr
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The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic β cell function, insulin secretion and lipid …
New Treatment Strategies for Dengue and Other Flaviviral Diseases
Av Jamie A. Goode, Gregory R. Bock
E-bok, 2006
2735 kr
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Dengue virus is a member of the Flaviviridae family, which includes viruses associated with human diseases such as yellow fever, Japanese encephalitis and hepatitis C. Dengue fever is transmitted by mosquitoes, principally Aedes aegypti . There are four serotypes of dengue virus, of which DENV-2 …
Decoding the Genomic Control of Immune Reactions
Av Jamie A. Goode, Gregory R. Bock
E-bok, 2007
2735 kr
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This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections. The assembled genome sequences now provide important opportunities for …
Novel and Re-emerging Respiratory Viral Diseases
Av Gregory R. Bock, Jamie A. Goode
Inbunden, 2008
2400 kr
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The past decade has seen mounting global concern regarding viral outbreaks such as SARS, avian influenza and West Nile virus. In 2004 and 2005, reports of bird-to-human, and possible human-to-human, transmissions of the H5N1 influenza viruses raised fears that these viruses could cause a pandemic …
Mitochondrial Biology
New Perspectives
Av Derek J. Chadwick, Jamie A. Goode
Inbunden, 2007
2327 kr
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With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of the current state-of-the-art in mitochondrial research. The book opens with the regulation of mitochondrial replication and biogenesis and reviews …
Inflammatory Bowel Disease
Crossroads of Microbes, Epithelium and Immune Systems
Av Derek J. Chadwick, Jamie A. Goode
Inbunden, 2004
2369 kr
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Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the exact cause of IBD remains undetermined, the condition appears to be related to a combination of …
Inflammatory Bowel Disease
Crossroads of Microbes, Epithelium and Immune Systems
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2005
2735 kr
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Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the exact cause of IBD remains undetermined, the condition appears to be related to a combination of …
Immunoinformatics
Bioinformatic Strategies for Better Understanding of Immune Function
Av Jamie A. Goode, Gregory R. Bock
E-bok, 2004
2735 kr
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The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the creation of the emerging field of immunoinformatics. …
Molecular Clocks and Light Signalling
Av Jamie A. Goode, Derek J. Chadwick
E-bok, 2004
2598 kr
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The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary feature of these biological clocks is their ability to entrain to environmental stimuli. The dominant stimulus comes from environmental light cues, …
Stem Cells
Nuclear Reprogramming and Therapeutic Applications
Av Novartis, Gregory R. Bock m. fl.
Inbunden, 2005
2267 kr
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Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated discussion from the world’s experts in this topic on the important ethical issues that are raised by …