Dev Bukhsh Singh – författare

Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life sciences. It presents a compendium of many important topics of current advanced research and basic principles/approaches easily applicable to diverse research settings. The content encompasses topics such as biological databases, sequence analysis, genome assembly, RNA sequence data analysis, drug design, and structural and functional analysis of proteins. In addition, it discusses computational approaches for vaccine design, systems biology and big data analysis, and machine learning in bioinformatics.It is a valuable source for bioinformaticians, computer biologists, and members of biomedical field who needs to learn bioinformatics approaches to apply to their research and lab activities. Covers basic and more advanced developments of bioinformatics with a diverse and interdisciplinary approach to fulfill the needs of readers from different backgrounds Explains in a practical way how to decode complex biological problems using computational approaches and resources Brings case studies, real-world examples and several protocols to guide the readers with a problem-solving approach

Genome Analysis: Principles and Methods provides recent and advanced information about genome analysis approaches and techniques to study and annotate the structure and function of the genome. It is a compendium of important topics such as NGS analysis, genome fragmentation and assembly, metagenomics, cloning and expression, physical marker analysis, transcriptome data analysis, sequence alignment and comparison, evolutionary analysis, SNP analysis, genome-based disease diagnosis and therapies, micro-RNAs, pharmacogenomics, genetic approaches to disease intervention, and challenges with opportunities in genome analysis and genomics, etc.The latest developments in the field are discussed, and key concepts are introduced to ensure readers understand advanced concepts and methodologies in the area. The book serves as a valuable guide to the present, emerging, and evolving research methodologies in the field.

Contains chapters written by leading global experts actively engaged in their respective research topicProvides a wide-ranging collection of 24 chapters related to the field of genomics and genome analysisPresents a broad picture of current, emerging, and evolving advances and applications of genomics

Medicinal Biotechnology: Methods and Applications covers a wide range of topics from traditional herbal medicine to recent plant and animal biotechnology approaches used for the production of vaccines, hormones, enzymes, edible medicinal products, herbal therapeutics, and other secondary metabolites. The book opens with a historical perspective of medicinal biotechnology which includes a discussion of successive development in the field of medicine, starting from early civilization up to current and advanced approaches and strategies.The book also provides a wide range of topics that include: a discussion engineering approaches in medicinal biotechnology, metabolomics, extraction of metabolites, personalization approaches, and strategies for the effective use of medicinal product and drugs; explanation of engineering approaches in medicinal biotechnology, metabolomics, extraction of metabolites, personalization approaches, and strategies for the effective use of medicinal product and drug; and coverage of specific knowledge on the production and use in vaccines, antibodies, and hormones.

Provides a discussion of the traditional medicine system and the role of herbsDiscusses plant and animal tissues culture/engineering approaches used to produce medicinal products such as vaccines, antibiotics, and hormonesHighlights the discussion of topics related to DNA profiling, genome editing, synthetic biology, bioprospecting, metabolomics, personalized medicine, and intellectual property rights in relation to the medicinal productEmphasizes the therapeutic potential of edible plant products and herbal therapeutics for chronic disease management

This book explores the pharmacological potentials of various classes of plant secondary metabolites. The initial chapter introduces the chemical diversity, biosynthesis pathways, and ecological functions of plant secondary metabolites. It discusses the pivotal role of transcription factors in regulating their production. Furthermore, the book examines the specific classes of secondary metabolites, such as phenolic compounds, terpenes, and anthocyanins, highlighting their properties and various applications across the food, cosmetics, and pharmaceutical industries. This book delves into emerging areas such as plant metabolites as nutraceuticals, the utilization of horticultural and vegetable crops for secondary metabolite production, and the exploration of staple crops for health improvements. The chapters discuss the applications of fungal endosymbionts and algal sources in shaping plant metabolite compositions. The chapters further review innovative techniques, such as hairy root engineering and recombinant systems, for enhancing metabolite production. The book concludes with a detailed overview of methods for isolating and identifying secondary metabolites. This book is an essential resource for students, researchers, and professionals of ethnopharmacology, pharmaceutical sciences, botany, and biomedical sciences.Key Features:Covers various classes of plant secondary metabolites and their pharmacological potentialsExplores the role of transcription factors in controlling secondary metabolite production in plantsDiscusses secondary metabolites from horticultural and vegetable crops, highlighting their pharmaceutical applicationsPresents techniques like hairy root engineering and recombinant systems for enhancing metabolite productionExamines lichen metabolites and their applications in human health, as well as metabolites from gymnosperms

This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics.

This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics.

It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules.

It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules.

This book provides an overview of the essential characteristics and clinical applications of therapeutic proteins against human diseases, including cancers, immune disorders, infections, and other diseases.