Apoptosis, or programmed cell death, is a necessary process by which a cell may die without adversely affecting its environment. It plays a crucial role in normal development, and in the body''s defence mechanisms against disease. Too much cell death is destructive, leading to neurodegenerative diseases and impaired development. Conversely, too litt

Although general morphological features have been used to consistently identify the changes in cell ultrastructure occurring during apoptosis, as distinct from necrosis, important advances have been achieved more recently in the investigation of the cellular and molecular aspects of this process. This book brings together the latest international research on the complex subject of programmed cell death, and covers such areas as the biochemical mechanisms, introduction of DNA fragmentation, enetic regulation, and the importance of apoptosis in the immune system, particularly during T-cell development, and in cancer. The comparison of a number of common signal transduction pathways with those involved in cell growth highlights an important relationship between apoptosis and the control of cell proliferation.

Although general morphological features have been used to consistently identify the changes in cell ultrastructure occurring during apoptosis, as distinct from necrosis, important advances have been achieved more recently in the investigation of the cellular and molecular aspects of this process. This book brings together the latest international research on the complex subject of programmed cell death, and covers such areas as the biochemical mechanisms, introduction of DNA fragmentation, enetic regulation, and the importance of apoptosis in the immune system, particularly during T-cell development, and in cancer. The comparison of a number of common signal transduction pathways with those involved in cell growth highlights an important relationship between apoptosis and the control of cell proliferation.

Combining architectural and social history, this open access book tells for the first time the in-depth story of Scotland’s new towns.One of the most significant episodes in modern architectural, urban and social history, Scotland’s postwar new towns offered new housing, new ways of life and new jobs. Begun between the late 1940s and the late 1960s, the new towns – East Kilbride, Glenrothes, Cumbernauld, Livingston and Irvine – were a key element of the planned Welfare State, attracting international attention and widespread publicity. These were places of architectural innovation, and economic and social change.Building Modern Scotland tells a new history of the new towns, combining architectural and social history to illustrate what was planned, what was built, and how these places were experienced by the communities who lived and worked in them. It positions the new towns at the heart of modern Scottish history, showing how they represented an ambition to make a modern, transformed nation. The book surveys each new town’s planning and design before turning to key topics such as housing, family life, work and opportunity, and community. Drawing on archives and oral history, the book will appeal to historians of modern architecture and design as well as readers interested in modern social history. It provides a new account of modern Scotland, its buildings, places and people, and argues that a better understanding of the new towns’ history and value should inform present-day decision-making.The ebook editions of this book are available open access under a CC BY-NC-ND 4.0 licence on bloomsburycollections.com. Open access was funded by the Leverhulme Trust.

Combining architectural and social history, this open access book tells for the first time the in-depth story of Scotland’s new towns.One of the most significant episodes in modern architectural, urban and social history, Scotland’s postwar new towns offered new housing, new ways of life and new jobs. Begun between the late 1940s and the late 1960s, the new towns – East Kilbride, Glenrothes, Cumbernauld, Livingston and Irvine – were a key element of the planned Welfare State, attracting international attention and widespread publicity. These were places of architectural innovation, and economic and social change.Building Modern Scotland tells a new history of the new towns, combining architectural and social history to illustrate what was planned, what was built, and how these places were experienced by the communities who lived and worked in them. It positions the new towns at the heart of modern Scottish history, showing how they represented an ambition to make a modern, transformed nation. The book surveys each new town’s planning and design before turning to key topics such as housing, family life, work and opportunity, and community. Drawing on archives and oral history, the book will appeal to historians of modern architecture and design as well as readers interested in modern social history. It provides a new account of modern Scotland, its buildings, places and people, and argues that a better understanding of the new towns’ history and value should inform present-day decision-making.The ebook editions of this book are available open access under a CC BY-NC-ND 4.0 licence on bloomsburycollections.com. Open access was funded by the Leverhulme Trust.

Apoptosis, or programmed cell death, is a necessary process by which a cell may die without adversely affecting its environment. It plays a crucial role in normal development, and in the body''s defence mechanisms against disease. Too much cell death is destructive, leading to neurodegenerative diseases and impaired development. Conversely, too litt

Apoptosis, or programmed cell death, is a necessary process by which a cell may die without adversely affecting its environment. It plays a crucial role in normal development, and in the body''s defence mechanisms against disease. Too much cell death is destructive, leading to neurodegenerative diseases and impaired development. Conversely, too litt

Although general morphological features have been used to consistently identify the changes in cell ultrastructure occurring during apoptosis, as distinct from necrosis, important advances have been achieved more recently in the investigation of the cellular and molecular aspects of this process. This book brings together the latest international research on the complex subject of programmed cell death, and covers such areas as the biochemical mechanisms, introduction of DNA fragmentation, enetic regulation, and the importance of apoptosis in the immune system, particularly during T-cell development, and in cancer. The comparison of a number of common signal transduction pathways with those involved in cell growth highlights an important relationship between apoptosis and the control of cell proliferation.

Although general morphological features have been used to consistently identify the changes in cell ultrastructure occurring during apoptosis, as distinct from necrosis, important advances have been achieved more recently in the investigation of the cellular and molecular aspects of this process. This book brings together the latest international research on the complex subject of programmed cell death, and covers such areas as the biochemical mechanisms, introduction of DNA fragmentation, enetic regulation, and the importance of apoptosis in the immune system, particularly during T-cell development, and in cancer. The comparison of a number of common signal transduction pathways with those involved in cell growth highlights an important relationship between apoptosis and the control of cell proliferation.

Combining architectural and social history, this open access book tells for the first time the in-depth story of Scotland’s new towns.One of the most significant episodes in modern architectural, urban and social history, Scotland’s postwar new towns offered new housing, new ways of life and new jobs. Begun between the late 1940s and the late 1960s, the new towns – East Kilbride, Glenrothes, Cumbernauld, Livingston and Irvine – were a key element of the planned Welfare State, attracting international attention and widespread publicity. These were places of architectural innovation, and economic and social change.Building Modern Scotland tells a new history of the new towns, combining architectural and social history to illustrate what was planned, what was built, and how these places were experienced by the communities who lived and worked in them. It positions the new towns at the heart of modern Scottish history, showing how they represented an ambition to make a modern, transformed nation. The book surveys each new town’s planning and design before turning to key topics such as housing, family life, work and opportunity, and community. Drawing on archives and oral history, the book will appeal to historians of modern architecture and design as well as readers interested in modern social history. It provides a new account of modern Scotland, its buildings, places and people, and argues that a better understanding of the new towns’ history and value should inform present-day decision-making.The ebook editions of this book are available open access under a CC BY-NC-ND 4.0 licence on bloomsburycollections.com. Open access was funded by the Leverhulme Trust.

Combining architectural and social history, this open access book tells for the first time the in-depth story of Scotland’s new towns.One of the most significant episodes in modern architectural, urban and social history, Scotland’s postwar new towns offered new housing, new ways of life and new jobs. Begun between the late 1940s and the late 1960s, the new towns – East Kilbride, Glenrothes, Cumbernauld, Livingston and Irvine – were a key element of the planned Welfare State, attracting international attention and widespread publicity. These were places of architectural innovation, and economic and social change.Building Modern Scotland tells a new history of the new towns, combining architectural and social history to illustrate what was planned, what was built, and how these places were experienced by the communities who lived and worked in them. It positions the new towns at the heart of modern Scottish history, showing how they represented an ambition to make a modern, transformed nation. The book surveys each new town’s planning and design before turning to key topics such as housing, family life, work and opportunity, and community. Drawing on archives and oral history, the book will appeal to historians of modern architecture and design as well as readers interested in modern social history. It provides a new account of modern Scotland, its buildings, places and people, and argues that a better understanding of the new towns’ history and value should inform present-day decision-making.The ebook editions of this book are available open access under a CC BY-NC-ND 4.0 licence on bloomsburycollections.com. Open access was funded by the Leverhulme Trust.

Apoptosis, or programmed cell death, is a necessary process by which a cell may die without adversely affecting its environment. It plays a crucial role in normal development, and in the body''s defence mechanisms against disease. Too much cell death is destructive, leading to neurodegenerative diseases and impaired development. Conversely, too litt