E. Vollmer – författare
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6 produkter
6 produkter
E-bok
PDF, Engelska, 20121 408 kr
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Due to the topology and structure of the lymph nodes, their role in the pathogenesis and development of diseases is a very special one. Each organ and even each organ-related region of the body has its own group of lymph nodes, specific topological reactions, such as in circumscribed inflammation or in the metastatic spread of malignant tumors. On the other hand, all the lymph nodes of an organism join in a uniform function effected by highly differentiated structures. Volume 84 of Current Topics in Pathology presents our current knowledge about the structure and reaction patterns of this "sec ondary" lymphoid organ. Despite our original intention to publish all the contributions in one book, it became necessary to divide them: Part 1 focuses on the involved nodal compartments, cell types, and functions, while Part 2 describes their reactions in inflammatory, neo plastic, and immune-deficient diseases. Even with the cooperation of more than 30 authors, the coverage cannot be exhaustive. The scope of both parts is limited to those reactions that can be described by direct and indirect morphological methods, including modern tech niques such as immune electron microscopy.
Häftad, Engelska, 2011
1 112 kr
Skickas inom 10-15 vardagar
Due to the topology and structure of the lymph nodes, their role in the pathogenesis and development of diseases is a very special one. Each organ and even each organ-related region of the body has its own group of lymph nodes, specific topological reactions, such as in circumscribed inflammation or in the metastatic spread of malignant tumors. On the other hand, all the lymph nodes of an organism join in a uniform function effected by highly differentiated structures. Volume 84 of Current Topics in Pathology presents our current knowledge about the structure and reaction patterns of this "sec ondary" lymphoid organ. Despite our original intention to publish all the contributions in one book, it became necessary to divide them: Part 1 focuses on the involved nodal compartments, cell types, and functions, while Part 2 describes their reactions in inflammatory, neo plastic, and immune-deficient diseases. Even with the cooperation of more than 30 authors, the coverage cannot be exhaustive. The scope of both parts is limited to those reactions that can be described by direct and indirect morphological methods, including modern tech niques such as immune electron microscopy.
E-bok
PDF, Engelska, 20121 408 kr
Läs direkt efter köp
This second volume reports on the reaction patterns of lymph nodes in neoplastic and immunodeficient diseases. Based on the contents of volume 1, it presents a detailed survey of lymph node structures and their cellular components under these conditions. The patterns of nodal reactions to the development and spread of cancer have recently been investigated and discussed by several authors. Here, the immediate interactions between tumor tissue and the regional nodes have been assessed in experimental models and in human material. Using modern morphological methods such as im munohistochemistry on the light and electron microscopic level, new insights have been gained into the stepwise process of lymphogenous metastasis. Macrophages/reticulum cells were found to playa signifi cant role in this process, which is duly emphasized. Based on appro priate animal models, one chapter focuses on various subtypes of these cellular elements and their role in the two separate phases of tumor spread and the development of true metastases. The induction of fibronectin in lymph nodes is effected by tumor cells forming a special part of the extracellular matrix. The multifunctional fibronec tin molecule serves as a mediator between tumor cells and fibroblasts, furthering the formation of tumor stroma. This volume also contains a comprehensive survey of primary im munodeficiency syndromes and their nodal manifestations, reference being made to the most recent immunological knowledge.
Häftad, Engelska, 2011
1 112 kr
Skickas inom 10-15 vardagar
This second volume reports on the reaction patterns of lymph nodes in neoplastic and immunodeficient diseases. Based on the contents of volume 1, it presents a detailed survey of lymph node structures and their cellular components under these conditions. The patterns of nodal reactions to the development and spread of cancer have recently been investigated and discussed by several authors. Here, the immediate interactions between tumor tissue and the regional nodes have been assessed in experimental models and in human material. Using modern morphological methods such as im munohistochemistry on the light and electron microscopic level, new insights have been gained into the stepwise process of lymphogenous metastasis. Macrophages/reticulum cells were found to playa signifi cant role in this process, which is duly emphasized. Based on appro priate animal models, one chapter focuses on various subtypes of these cellular elements and their role in the two separate phases of tumor spread and the development of true metastases. The induction of fibronectin in lymph nodes is effected by tumor cells forming a special part of the extracellular matrix. The multifunctional fibronec tin molecule serves as a mediator between tumor cells and fibroblasts, furthering the formation of tumor stroma. This volume also contains a comprehensive survey of primary im munodeficiency syndromes and their nodal manifestations, reference being made to the most recent immunological knowledge.
E-bok
PDF, Engelska, 20121 408 kr
Läs direkt efter köp
Häftad, Engelska, 2011
1 112 kr
Skickas inom 10-15 vardagar
During the past years a considerable number of books have been published on atherosclerosis research. Much attention has been focused on the biochemical properties of lipoproteins and the involvement of lipoprotein metabolism in the atherogenic process. The monograph presented here focuses on morphologic studies of atherosclerotic plaque. One chapter deals with the pathobiochemical changes in the arterial wall at the inception of atherosclerosis. Recently the specific role of macro phages in atherogenesis has been the object of much interest. A morphological study of their role and differentiation is the topic of another chapter. This is complemented by a study of lipoprotein receptors on macrophages and smooth muscle cells both in cell culture and in situ, based on electron microscopic investiga- tions. An immunohistological study on the in situ localization promotes our understanding oflipoprotein metabolism in the arterial wall. The morphologic aspects of more advanced lesions are present- ed in studies of collagens and angiogenic processes in the athero- sclerotic vessel wall.Experimental investigations have also been useful for understanding the pathogenetic aspects of atherosclerosis; one crrapter concentrates on the metabolism of fibromuscular and atheromatous plaques in an experimental model. A final chapter deals with transplant arteriopathy and its possible parallels with conventional atherosclerosis. The widespread discussion of athero- genesis is focused on the arterial wall and its morphological alter- ations, emphasizing once again the importance of morphological research for understanding the pathological basis of disease. Borstel and Magdeburg E. VOLLMER and A.