Eiman Abdel Meguid – författare

The intestine is among the leading organs, in which several cutting edge in vitro and in vivo research tools and approaches have recently been developed and used to investigate stem cell biology/function, and the potential applications of stem cells in the treatment of intestinal diseases. These cutting-edge research tools and approaches involve human and murine organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases.

Stem Cell Innovation in Health and Disease: Volume 1: The Intestine contains two major sections describing cutting edge research for understanding stem cell functions in the intestine, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model intestinal diseases, through the cutting-edge research, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of intestinal diseases/disorders. This volume, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the intestine in the real world.

This book highlights the integration of science and imaging and demonstrates how we can teach and learn in a much more accessible, innovative, and engaging way using technology.

This volume is particularly focused on three main themes: advanced microscopy, anatomy education, and radiology visualisation related to patient care. The chapters pertaining to advanced microscopy convey complex biomedical information by visual means. These chapters provide both an overview on the principles of microscopy and specific applications of microscopy that have led to groundbreaking discoveries. Chapters pertaining to education summarise the recent trends in teaching gross and microscopic anatomy and emphasise the creation and use of novel tools to support student learning. Lastly, the radiological visualisation segment dives into the history of radiographic imaging and highlights the profound effect technology has had on improving patient outcomes.

This volume will be of particular interest to many; the scope of this book encompasses medicine, dentistry, allied health professions, biomedical sciences, anatomy and histology education, radiology, and microscopy. Students, researchers, educators, and clinicians will learn something new, be stimulated to ask innovative questions, and be inspired to continue the technological advancements pushing science forward.