F. Schubert – författare

Biosensors combine the unique properties of biological systems to selectively recognize and convert molecules with the benefits of physicochemical sensor technology, such as high sensitivity, simplicity of operation and mass production, and modern electronics. Consequently, their development is closely related to progress in two branches of high technology - biotechnology and microelectronics. This book not only presents the state-of-the-art of biosensor research and development to the specialist, but also introduces the layman to the fundamentals of the subject. The relevant features of physicochemical transducer elements as well as biochemical recognition molecules (enzymes, antibodies, receptors) are outlined. Biochemical and biotechnological aspects of biomolecule immobilization and the interplay of biochemical reactions and mass transfer processes are comprehensively treated with regard to their impact on successful sensor design. Examples of immobilization methods are described in detail. The employment of coupled enzyme reactions, higher integrated biocatalytic systems (cell organelles, microbes, tissue sections) and immunocomponents in biosensors is covered extensively. Optical, thermometric, piezoelectric and particularly electrochemical biosensors for more than 100 analytes are presented, including immunosensors. The relative merits and limits of biosensors are discussed using several examples of their application in clinical chemistry, bioprocess control and environmental monitoring. Finally, the application of biosensors in medicine, biotechnology, food industry and environmental control is discussed, including commercialization and problems to be addressed in future research.

The role of energy in the modern world goes beyond mere technology and economics to influence welfare, the environment, the quality of life and, in broad terms, civilization itself. Since the Industrial Revolution, energy conservation technology has been at the forefront of the innovation required to satisfy the needs of mankind and, more than any other, this technology has always depended on the performance of the materials used. In this, the report of the Fifth Liege Conference devoted to a review of the work of the European Materials Collaborative Programmes, the results of the programmes are presented along the following technology-oriented themes: steam-power plant; gas turbines; diesel engines; advanced combustion; and perspectives. The book thus presents an up-to-date reference on materials technologies in energy conversion from fossil fuels and materials for high-efficiency, low-emission systems.

Volume I provides an in-depth discussion of the most recent developments of crucical biosensor components. It concentrates on the interface between the analyte phase and the detector, namely, the implementation of novel recognition elements, including nucleic acids, and of leading-edge technology in the construction of responsive thin layers. Thus, the reader can obtain a foretaste of achievable future progress in the field.

Volume I provides an in-depth discussion of the most recent developments of crucical biosensor components. It concentrates on the interface between the analyte phase and the detector, namely, the implementation of novel recognition elements, including nucleic acids, and of leading-edge technology in the construction of responsive thin layers. Thus, the reader can obtain a foretaste of achievable future progress in the field.