Gaetano Thiene – författare

Arrhythmogenic right ventricular dysplasia is an inherited heart muscle disorder that may cause abnormal electrical heart rhythms and weakening of the pumping action of the heart, resulting in sudden death. The electrocardiograph (EKG) is used to diagnose the disease, so it is important for cardiac electrophysiologists to be familiar with the disease and to be able� to recognize it on the EKG.

This issue of Cardiac Electrophysiology Clinics covers arrhythmias in athletes, which can be a cause of morbidity and mortality. Expert authors review the most current information available about management of ventricular arrhythmias, atrial fibrillation, bradyarrhythmias, syncope and other conditions. Preparticipation screening, defibrillator use, and prevention are also discussed. Keep up-to-the-minute with the latest developments in this important aspect of cardiac electrophysiology practice.

Cardiac tumors were once a nosographic entity of scarce clinical interest because of the rarity and of the intrinsic diagnostic and therapeutic impossibilities, and were considered a fatal morbid entity.

Cardiac tumors were once a nosographic entity of scarce clinical interest because of the rarity and of the intrinsic diagnostic and therapeutic impossibilities, and were considered a fatal morbid entity.

Cardiac valve diseases are a major cause of morbidity and mortality around the globe. In third world countries, inflammatory rheumatic valve disease in the young represents an endemic calamity, while in Western countries, degenerative valve diseases like senile calcific aortic stenosis and mitral valve prolapse as a result of mucoid degeneration with incompetence are major causes of death in adults/the elderly. Since the 1960s, surgical valve replacement has been the only treatment option, requiring sternotomy, cardiopulmonary bypass and cardiac arrest. Permanent anticoagulation for mechanical valves and the limited durability of biological valves constituted significant drawbacks; moreover, these surgeries often requires surgical replacement.The cardiac registry at the University of Padua, Italy, has gathered more than twelve hundred cases of failed prosthetic valves, offering a unique resource for teaching and research. Conservative valve repair using minimally invasive technique showed that replacement of the native valve with sternotomy can be spared. Moreover, in the last decade venous or arterial approaches like TAVI were developed. Presenting the essential surgical and interventional anatomy and pathology in detail, this book offers a valuable tool for cardiologists, cardiac surgeons and pathologists, as well as people in training and scientists working in the field of medical devices and biological compatibility.

The objective of this text-atlas is to examine the bicuspid aortic valve syndrome (BAV) holistically. The various chapters deal with epidemiology, morphological spectrum, embryology, associated congenital heart disease, genetics and familiarity, natural history, including clinically relevant valve complications (stenosis, regurgitation, endocarditis) and/or vascular complications affecting the thoracic aorta (dilatation, aneurysm, dissection) that require close clinical follow-up. In addition, multimodal imaging and surgical and transcatheter therapeutic options will be described. To the best of our knowledge, this will be the first illustrated monograph on this topic and will be enriched with numerous original illustrations.Offering in-depth visual representations, clinical insights and comprehensive data, it will provide experts with the tools they need to improve understanding and treatment of this unique heart conition, advancing patient care and research in the field of cardiovascular health.

This book covers all the recent research highlights of arrhythmogenic right ventr- ular cardiomyopathy/dysplasia (ARVC/D), a recently discovered heart muscle d- ease which is a major threat to the life of affected young people. It summarizes ne- ly 25 years of investigation on the etiology, genetics, pathology, clinical features, - agnosis, and treatment of ARVC/D. In particular, a 5-year research program supported by grants from both the European Community and the National Heart, Lung and Blood Institutes has contributed to the discovery of seven disease-causing genes, thus opening new avenues for the early identification of affected patients and prevention of sudden death. A Workshop was held in Venice, Italy, October 3, 2005, as part of the Venice - rhythmia Meeting, where the European and American investigators presented and discussed several major achievements which are now reported in this book.As a - sult of these coordinated efforts, great advances have been made in the recognition and understanding of the disease, which are summarized in this book.

This text atlas focuses on the pathology and molecular genetics of sudden cardiac death in the young and in athletes, presenting the state of the art in the field as the basis for development and implementation of more effective prevention strategies, including, ultimately, molecular therapy that will cure the underlying biological defect. A wealth of high-resolution color images, accompanied by clear supporting text, are presented to document the anatomic pathology of the cardiac diseases most frequently responsible for sudden cardiac death in this population, including coronary artery diseases, cardiomyopathies, myocarditis, valve diseases, conduction system abnormalities, congenital heart diseases, and ion channel diseases. The role of the molecular autopsy in overcoming the limitations of morphological investigations and offering new insights and avenues for prevention is explained. The approach is, however, interdisciplinary, with close attention also to epidemiologic and clinical aspects. The authors draw throughout on their experience gained over 30 years in the course of a prospective study carried out in the Veneto Region, North East Italy. This text atlas will be of great value not only for cardiologists but also for geneticists, sports physicians, and residents in cardiology and pathology.

This book covers all the recent research highlights of arrhythmogenic right ventr- ular cardiomyopathy/dysplasia (ARVC/D), a recently discovered heart muscle d- ease which is a major threat to the life of affected young people. It summarizes ne- ly 25 years of investigation on the etiology, genetics, pathology, clinical features, - agnosis, and treatment of ARVC/D. In particular, a 5-year research program supported by grants from both the European Community and the National Heart, Lung and Blood Institutes has contributed to the discovery of seven disease-causing genes, thus opening new avenues for the early identification of affected patients and prevention of sudden death. A Workshop was held in Venice, Italy, October 3, 2005, as part of the Venice - rhythmia Meeting, where the European and American investigators presented and discussed several major achievements which are now reported in this book.As a - sult of these coordinated efforts, great advances have been made in the recognition and understanding of the disease, which are summarized in this book.