George Davey Smith – författare

This issue forms part of a series of expert reviews on selected health topics in fields where significant new developments are occurring. It is an invaluable reference source and allows those working in other specialities and younger clinicians and scientists to update their knowledge in important and well-defined subject areas.

The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.

Leading researchers in the social sciences describe and explain the unequal chances of long and healthy life between social groups, ethnic groups, men and women and geographical areas.

The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.

Systematic Reviews in Health Research

Explore the cutting-edge of systematic reviews in healthcare

In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including:

Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis Thorough update of 15 chapters focusing on systematic reviews of interventions Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org)

A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.

Systematic Reviews in Health Research

Explore the cutting-edge of systematic reviews in healthcare

In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including:

Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis Thorough update of 15 chapters focusing on systematic reviews of interventions Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org)

A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.

Systematic Reviews in Health ResearchExplore the cutting-edge of systematic reviews in healthcareIn this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including: Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysisThorough update of 15 chapters focusing on systematic reviews of interventionsAccess to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org)A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.

In human genetics, causal inference methods leverage large omics data sets and phenotypic information to decipher various cause-and-effect relationships in human health and disease (e.g., smoking and lung cancer). The focus of such work is typically on modifiable variables (e.g., behavior or environmental exposure) that impact disease onset, progression, and outcome. A better understanding of these variables can lead to interventions and therapeutics that have a desirable impact on public health.Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines advances in causal inference approaches in human genetics and how they are being used to enhance our understanding of human development and disease. The contributors discuss family-based study designs for causal inference, including twin designs, adoption designs, and in vitro fertilization designs, that separate inherited factors from perinatal environmental exposures. They also review various types of Mendelian randomization—a population-based approach that is growing in utility and popularity—as well as their integration with family-based designs.The use of these approaches to investigate causal mechanisms in specific scenarios (e.g., maternal smoking during pregnancy and ADHD in offspring) is also covered. This volume is therefore an essential read for geneticists, epidemiologists, and all biomedical scientists and public health professionals dedicated to using genetic information to improve human health.

Relentlessly, the wide health gap between different groups of people living in Britain continues to get even wider. This book presents new evidence (which was not available to the government's Independent Inquiry into Inequalities in Health) on the size of the gap, and the extent to which the gap is widening. In particular, new geographical data are presented and displayed in striking graphical form.It challenges whether the government is concerned enough about reducing inequalities and highlights the living conditions of the million people living in the least healthy areas in Britain. It presents explanations for the widening health gap, and addresses the implications of this major social problem. In the light of this evidence the authors put forward social policies which will reduce the health gap in the future.The widening gap synthesises all the information available to date and should be read alongside the report of the evidence presented to the Independent Inquiry into Inequalities in Health (Inequalities in health, The Policy Press, 1999) and by all those concerned with reducing health inequalities.Studies in poverty, inequality and social exclusion seriesSeries Editor: David Gordon, Director, Townsend Centre for International Poverty Research.Poverty, inequality and social exclusion remain the most fundamental problems that humanity faces in the 21st century. This exciting series, published in association with the Townsend Centre for International Poverty Research at the University of Bristol, aims to make cutting-edge poverty related research more widely available. For other titles in this series, please follow the series link from the main catalogue page.

The Acheson Inquiry was the most important government-backed examination into inequalities in health in the past 20 years. However, much of the detailed evidence presented to the Inquiry has not been published - until now.This book presents 17 chapters of evidence commissioned by the Acheson Inquiry to inform their work. It provides a 'state of the art' review, by leading experts, into aspects of inequalities in health among:Mothers/families/childrenYouthAdults of working ageOlder peopleHousingSocial environmentPoverty and incomeThe NHSNutritionEducationAreasEthnicityTransport/pollution/material environmentGenderMental healthHealth-related behavioursOral health· Inequalities in health: The evidence is important reading for academics in the social and medical sciences, students, medical professionals and people working within the fields of health and community care.Studies in poverty, inequality and social exclusion seriesSeries Editor: David Gordon, Director, Townsend Centre for International Poverty Research.Poverty, inequality and social exclusion remain the most fundamental problems that humanity faces in the 21st century. This exciting series, published in association with the Townsend Centre for International Poverty Research at the University of Bristol, aims to make cutting-edge poverty related research more widely available. For other titles in this series, please follow the series link from the main catalogue page.

Inequalities in health, in terms of both empirical evidence and policies to tackle their reduction, are currently high on the research and political agendas. This reader provides two centuries of historical context to the current debate. Poverty, inequality and health in Britain: 1800-2000 presents extracts from classic texts on the subject of poverty, inequality and health in Britain. For the first time, these key resources are presented in a single volume. Each extract is accompanied by information about the author, and an introduction by the editors draws together themes of change and continuity over two hundred years. Some extracts present empirical evidence of the relationship of poverty and health, while others describe the gritty reality of the everyday struggles of the poor.This book will be of interest to students, researchers, academics and policy makers working in a range of disciplines: the social sciences, historical studies and health. It will also be of interest to all those concerned with tackling health inequalities and social justice generally.Studies in poverty, inequality and social exclusion seriesSeries Editor: David Gordon, Director, Townsend Centre for International Poverty Research.Poverty, inequality and social exclusion remain the most fundamental problems that humanity faces in the 21st century. This exciting series, published in association with the Townsend Centre for International Poverty Research at the University of Bristol, aims to make cutting-edge poverty related research more widely available. For other titles in this series, please follow the series link from the main catalogue page.

The lifecourse perspective on adult health and on health inequalities in particular, is one of the most important recent developments in epidemiology and public health. This book brings together, in a single volume, the work of one of the most distinguished academics in the field. It is the first to specifically take a lifecourse approach to health inequalities and will be essential reading for academics, students and policy makers with an interest in public health, epidemiology, health promotion and social policy.

This Handbook is the definitive resource for anyone wishing to quickly look up and understand key concepts and measurements relating to socioeconomic position and inequalities. A range of key concepts is defined and measures of socioeconomic position and inequality described. Alphabetical listings, cross-referencing, graphs and worked examples, references to web and other sources of further information, all contribute to making the Handbook both engaging and accessible for a wide audience.For students, academics and others involved in social science research it answers questions such as:· 'What's the official government measure of poverty?' · 'What factors make up the Townsend Index of Deprivation?'· 'What is a gini coefficient?'· 'I have to write a report on tackling inequalities in my area - what are the key issues I should consider before I begin?'For practitioners, policy makers, journalists and others who must read, understand and use research in fields as diverse as health, criminology, education, the environment, transport and housing it provides a one-stop, authoritative guide to making sense of and evaluating the significance of often complex methodologies.The authors are all eminent researchers in the field of health inequalities. They have together produced two glossaries for the Journal of Epidemiology and Community Health and have published a large number of books and articles in learned academic journals.

Genetic epidemiology is a very rapidly developing field that has acquired a central role in modern biomedical science. Until now there has been no comprehensive introductory text for students and academics who do not have specialised training in statistics or genetics. This book begins with a primer in human molecular genetics and then examines standard methods in population genetics and genetic epidemiology required for an adequate grounding in the field. Among much else, the book contains discussion of the public health aspects of the new genetics, and of epidemiological methods for studying genes and environmental factors in complex diseases.Written by leading international experts and supplemented by a glossary and in-chapter guides to further reading, this essential textbook will be widely welcomed by teachers and students on many courses internationally.

Genetic epidemiology is a very rapidly developing field that has acquired a central role in modern biomedical science. Until now there has been no comprehensive introductory text for students and academics who do not have specialised training in statistics or genetics. This book begins with a primer in human molecular genetics and then examines standard methods in population genetics and genetic epidemiology required for an adequate grounding in the field. Among much else, the book contains discussion of the public health aspects of the new genetics, and of epidemiological methods for studying genes and environmental factors in complex diseases.Written by leading international experts and supplemented by a glossary and in-chapter guides to further reading, this essential textbook will be widely welcomed by teachers and students on many courses internationally.