Julian P. T. Higgins – författare

Systematic Reviews in Health Research

Explore the cutting-edge of systematic reviews in healthcare

In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including:

Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis Thorough update of 15 chapters focusing on systematic reviews of interventions Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org)

A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.

Systematic Reviews in Health Research

Explore the cutting-edge of systematic reviews in healthcare

In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including:

Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis Thorough update of 15 chapters focusing on systematic reviews of interventions Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org)

A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.

The revised edition of the Handbook offers the only guide on how to conduct, report and maintain a Cochrane Review 


The second edition of The Cochrane Handbook for Systematic Reviews of Interventions contains essential guidance for preparing and maintaining Cochrane Reviews of the effects of health interventions. Designed to be an accessible resource, the Handbook will also be of interest to anyone undertaking systematic reviews of interventions outside Cochrane, and many of the principles and methods presented are appropriate for systematic reviews addressing research questions other than effects of interventions.

This fully updated edition contains extensive new material on systematic review methods addressing a wide-range of topics including network meta-analysis, equity, complex interventions, narrative synthesis, and automation. Also new to this edition, integrated throughout the Handbook, is the set of standards Cochrane expects its reviews to meet. 

Written for review authors, editors, trainers and others with an interest in Cochrane Reviews, the second edition of The Cochrane Handbook for Systematic Reviews of Interventions continues to offer an invaluable resource for understanding the role of systematic reviews, critically appraising health research studies and conducting reviews. 

The revised edition of the Handbook offers the only guide on how to conduct, report and maintain a Cochrane Review 
The second edition of The Cochrane Handbook for Systematic Reviews of Interventions contains essential guidance for preparing and maintaining Cochrane Reviews of the effects of health interventions. Designed to be an accessible resource, the Handbook will also be of interest to anyone undertaking systematic reviews of interventions outside Cochrane, and many of the principles and methods presented are appropriate for systematic reviews addressing research questions other than effects of interventions.This fully updated edition contains extensive new material on systematic review methods addressing a wide-range of topics including network meta-analysis, equity, complex interventions, narrative synthesis, and automation. Also new to this edition, integrated throughout the Handbook, is the set of standards Cochrane expects its reviews to meet. Written for review authors, editors, trainers and others with an interest in Cochrane Reviews, the second edition of The Cochrane Handbook for Systematic Reviews of Interventions continues to offer an invaluable resource for understanding the role of systematic reviews, critically appraising health research studies and conducting reviews.

The revised edition of the Handbook offers the only guide on how to conduct, report and maintain a Cochrane Review 


The second edition of The Cochrane Handbook for Systematic Reviews of Interventions contains essential guidance for preparing and maintaining Cochrane Reviews of the effects of health interventions. Designed to be an accessible resource, the Handbook will also be of interest to anyone undertaking systematic reviews of interventions outside Cochrane, and many of the principles and methods presented are appropriate for systematic reviews addressing research questions other than effects of interventions.

This fully updated edition contains extensive new material on systematic review methods addressing a wide-range of topics including network meta-analysis, equity, complex interventions, narrative synthesis, and automation. Also new to this edition, integrated throughout the Handbook, is the set of standards Cochrane expects its reviews to meet. 

Written for review authors, editors, trainers and others with an interest in Cochrane Reviews, the second edition of The Cochrane Handbook for Systematic Reviews of Interventions continues to offer an invaluable resource for understanding the role of systematic reviews, critically appraising health research studies and conducting reviews. 

A clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studiesThe first edition of this text was widely acclaimed for the clarity of the presentation, and quickly established itself as the definitive text in this field. The fully updated second edition includes new and expanded content on avoiding common mistakes in meta-analysis, understanding heterogeneity in effects, publication bias, and more. Several brand-new chapters provide a systematic "how to" approach to performing and reporting a meta-analysis from start to finish.Written by four of the world's foremost authorities on all aspects of meta-analysis, the new edition: Outlines the role of meta-analysis in the research processShows how to compute effects sizes and treatment effectsExplains the fixed-effect and random-effects models for synthesizing dataDemonstrates how to assess and interpret variation in effect size across studiesExplains how to avoid common mistakes in meta-analysisDiscusses controversies in meta-analysisIncludes access to a companion website containing videos, spreadsheets, data files, free software for prediction intervals, and step-by-step instructions for performing analyses using Comprehensive Meta-Analysis (CMA)Download videos, class materials, and worked examples at www.Introduction-to-Meta-Analysis.com"This book offers the reader a unified framework for thinking about meta-analysis, and then discusses all elements of the analysis within that framework. The authors address a series of common mistakes and explain how to avoid them. As the editor-in-chief of the American Psychologist and former editor of Psychological Bulletin, I can say without hesitation that the quality of manuscript submissions reporting meta-analyses would be vastly better if researchers read this book."—Harris Cooper, Hugo L. Blomquist Distinguished Professor Emeritus of Psychology and Neuroscience, Editor-in-chief of the American Psychologist, former editor of Psychological Bulletin"A superb combination of lucid prose and informative graphics, the authors provide a refreshing departure from cookbook approaches with their clear explanations of the what and why of meta-analysis. The book is ideal as a course textbook or for self-study. My students raved about the clarity of the explanations and examples." —David Rindskopf, Distinguished Professor of Educational Psychology, City University of New York, Graduate School and University Center, & Editor of the Journal of Educational and Behavioral Statistics"The approach taken by Introduction to Meta-analysis is intended to be primarily conceptual, and it is amazingly successful at achieving that goal. The reader can comfortably skip the formulas and still understand their application and underlying motivation. For the more statistically sophisticated reader, the relevant formulas and worked examples provide a superb practical guide to performing a meta-analysis. The book provides an eclectic mix of examples from education, social science, biomedical studies, and even ecology. For anyone considering leading a course in meta-analysis, or pursuing self-directed study, Introduction to Meta-analysis would be a clear first choice." —Jesse A. Berlin, SCD

A clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studies

The first edition of this text was widely acclaimed for the clarity of the presentation, and quickly established itself as the definitive text in this field. The fully updated second edition includes new and expanded content on avoiding common mistakes in meta-analysis, understanding heterogeneity in effects, publication bias, and more. Several brand-new chapters provide a systematic "how to" approach to performing and reporting a meta-analysis from start to finish.

Written by four of the world''s foremost authorities on all aspects of meta-analysis, the new edition:

Outlines the role of meta-analysis in the research process Shows how to compute effects sizes and treatment effects Explains the fixed-effect and random-effects models for synthesizing data Demonstrates how to assess and interpret variation in effect size across studies Explains how to avoid common mistakes in meta-analysis Discusses controversies in meta-analysis Includes access to a companion website containing videos, spreadsheets, data files, free software for prediction intervals, and step-by-step instructions for performing analyses using Comprehensive Meta-Analysis (CMA)

Download videos, class materials, and worked examples at www.Introduction-to-Meta-Analysis.com

"This book offers the reader a unified framework for thinking about meta-analysis, and then discusses all elements of the analysis within that framework. The authors address a series of common mistakes and explain how to avoid them. As the editor-in-chief of the American Psychologist and former editor of Psychological Bulletin, I can say without hesitation that the quality of manuscript submissions reporting meta-analyses would be vastly better if researchers read this book."—Harris Cooper, Hugo L. Blomquist Distinguished Professor Emeritus of Psychology and Neuroscience, Editor-in-chief of the American Psychologist, former editor of Psychological Bulletin

"A superb combination of lucid prose and informative graphics, the authors provide a refreshing departure from cookbook approaches with their clear explanations of the what and why of meta-analysis. The book is ideal as a course textbook or for self-study. My students raved about the clarity of the explanations and examples." —David Rindskopf, Distinguished Professor of Educational Psychology, City University of New York, Graduate School and University Center, & Editor of the Journal of Educational and Behavioral Statistics

"The approach taken by Introduction to Meta-analysis is intended to be primarily conceptual, and it is amazingly successful at achieving that goal. The reader can comfortably skip the formulas and still understand their application and underlying motivation. For the more statistically sophisticated reader, the relevant formulas and worked examples provide a superb practical guide to performing a meta-analysis. The book provides an eclectic mix of examples from education, social science, biomedical studies, and even ecology. For anyone considering leading a course in meta-analysis, or pursuing self-directed study, Introduction to Meta-analysis would be a clear first choice." —Jesse A. Berlin, ScD

A clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studies

The first edition of this text was widely acclaimed for the clarity of the presentation, and quickly established itself as the definitive text in this field. The fully updated second edition includes new and expanded content on avoiding common mistakes in meta-analysis, understanding heterogeneity in effects, publication bias, and more. Several brand-new chapters provide a systematic "how to" approach to performing and reporting a meta-analysis from start to finish.

Written by four of the world''s foremost authorities on all aspects of meta-analysis, the new edition:

Outlines the role of meta-analysis in the research process Shows how to compute effects sizes and treatment effects Explains the fixed-effect and random-effects models for synthesizing data Demonstrates how to assess and interpret variation in effect size across studies Explains how to avoid common mistakes in meta-analysis Discusses controversies in meta-analysis Includes access to a companion website containing videos, spreadsheets, data files, free software for prediction intervals, and step-by-step instructions for performing analyses using Comprehensive Meta-Analysis (CMA)

Download videos, class materials, and worked examples at www.Introduction-to-Meta-Analysis.com

"This book offers the reader a unified framework for thinking about meta-analysis, and then discusses all elements of the analysis within that framework. The authors address a series of common mistakes and explain how to avoid them. As the editor-in-chief of the American Psychologist and former editor of Psychological Bulletin, I can say without hesitation that the quality of manuscript submissions reporting meta-analyses would be vastly better if researchers read this book."—Harris Cooper, Hugo L. Blomquist Distinguished Professor Emeritus of Psychology and Neuroscience, Editor-in-chief of the American Psychologist, former editor of Psychological Bulletin

"A superb combination of lucid prose and informative graphics, the authors provide a refreshing departure from cookbook approaches with their clear explanations of the what and why of meta-analysis. The book is ideal as a course textbook or for self-study. My students raved about the clarity of the explanations and examples." —David Rindskopf, Distinguished Professor of Educational Psychology, City University of New York, Graduate School and University Center, & Editor of the Journal of Educational and Behavioral Statistics

"The approach taken by Introduction to Meta-analysis is intended to be primarily conceptual, and it is amazingly successful at achieving that goal. The reader can comfortably skip the formulas and still understand their application and underlying motivation. For the more statistically sophisticated reader, the relevant formulas and worked examples provide a superb practical guide to performing a meta-analysis. The book provides an eclectic mix of examples from education, social science, biomedical studies, and even ecology. For anyone considering leading a course in meta-analysis, or pursuing self-directed study, Introduction to Meta-analysis would be a clear first choice." —Jesse A. Berlin, ScD