Giuseppe Micieli – författare
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11 produkter
11 produkter
E-bok
Engelska, 20141 143 kr
Läs direkt efter köp
Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately, during the last years numerous promising drugs th
Häftad, Engelska, 2018
968 kr
Skickas inom 10-15 vardagar
Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately, during the last years numerous promising drugs that showed neuroprotection in the experimental setting failed to translate into the clinic because of their toxicity or lack of efficacy.Researchers in the field now face the crucial need to develop effective stroke therapies and successfully translate novel strategies into the clinical setting. Rational Basis for Clinical Translation in Stroke Therapy presents the most recent promising preclinical approaches and the most updated clinical evidence for treating stroke patients. By bringing together the experience of accomplished stroke researchers and clinicians, the book is a useful tool for improving the treatment and management of stroke patients.The book describes current approaches for the management of stroke patients including thrombolysis and mechanical recanalization procedures as well as other clinically relevant topics such as diagnosis, imaging, risk factors, and prevention. Also described are emerging interventions based on the use of stem cells, botulinum toxin, and antidepressants which complement emergency stroke treatment and conventional rehabilitation procedures. Clinical approaches are integrated with the most promising therapeutic opportunities based on targeting the immune system, hypothermia, and postconditioning. The book also covers issues related to the improvement of R&D strategies in stroke therapeutics, aimed at the implementation of preclinical approaches with stroke model guidelines and at the optimization of clinical trial design. This volume is a reference for all those interested in the rational development of novel stroke therapeutics.
Inbunden, Engelska, 2014
2 919 kr
Skickas inom 10-15 vardagar
Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately, during the last years numerous promising drugs that showed neuroprotection in the experimental setting failed to translate into the clinic because of their toxicity or lack of efficacy.Researchers in the field now face the crucial need to develop effective stroke therapies and successfully translate novel strategies into the clinical setting. Rational Basis for Clinical Translation in Stroke Therapy presents the most recent promising preclinical approaches and the most updated clinical evidence for treating stroke patients. By bringing together the experience of accomplished stroke researchers and clinicians, the book is a useful tool for improving the treatment and management of stroke patients.The book describes current approaches for the management of stroke patients including thrombolysis and mechanical recanalization procedures as well as other clinically relevant topics such as diagnosis, imaging, risk factors, and prevention. Also described are emerging interventions based on the use of stem cells, botulinum toxin, and antidepressants which complement emergency stroke treatment and conventional rehabilitation procedures. Clinical approaches are integrated with the most promising therapeutic opportunities based on targeting the immune system, hypothermia, and postconditioning. The book also covers issues related to the improvement of R&D strategies in stroke therapeutics, aimed at the implementation of preclinical approaches with stroke model guidelines and at the optimization of clinical trial design. This volume is a reference for all those interested in the rational development of novel stroke therapeutics.
E-bok
PDF, Engelska, 20141 143 kr
Läs direkt efter köp
Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately, during the last years numerous promising drugs th
Inbunden, Engelska, 2020
1 560 kr
Skickas inom 10-15 vardagar
This book adopts a novel approach: procedures: instead of discussing the diagnostic categories of neurological syndromes, it focuses on the symptoms of common neurological presentations (especially in the emergency room or on the ward), and the diagnostic hypotheses that can be validated or rejected case by case as a result. Each chapter covers one of the main symptoms of emergencies in neurology – from transient consciousness disturbances to focal deficits, acute muscular disorders, respiratory insufficiency in neurological disorders, headaches, delirium, seizures and epileptic status, para-and tetraplegia, and head trauma, to acute functional disorders – and includes tables and figures to allow readers to gain a quick and easy, yet comprehensive overview of the topic. The book guides readers through various scenarios generated by the onset of symptoms, the clinical tools for differential diagnostics, and the principles of acute and post-acute phase therapy, managed by decision algorithms supported by the most recent scientific evidence.The resulting precedural profile – created through the collaboration of over 80 specialists in neurology or other disciplines – makes this text a valuable tool for neurologists, neurology residents and allied professionals in their daily clinical practice, as well as medical students.
E-bok
PDF, Engelska, 20201 459 kr
Läs direkt efter köp
This book adopts a novel approach: procedures: instead of discussing the diagnostic categories of neurological syndromes, it focuses on the symptoms of common neurological presentations (especially in the emergency room or on the ward), and the diagnostic hypotheses that can be validated or rejected case by case as a result. Each chapter covers one of the main symptoms of emergencies in neurology – from transient consciousness disturbances to focal deficits, acute muscular disorders, respiratory insufficiency in neurological disorders, headaches, delirium, seizures and epileptic status, para-and tetraplegia, and head trauma, to acute functional disorders – and includes tables and figures to allow readers to gain a quick and easy, yet comprehensive overview of the topic.
The book guides readers through various scenarios generated by the onset of symptoms, the clinical tools for differential diagnostics, and the principles of acute and post-acute phase therapy, managed by decision algorithms supported by the most recent scientific evidence.
The resulting precedural profile – created through the collaboration of over 80 specialists in neurology or other disciplines – makes this text a valuable tool for neurologists, neurology residents and allied professionals in their daily clinical practice, as well as medical students.
Häftad, Engelska, 2021
1 116 kr
Skickas inom 10-15 vardagar
This book adopts a novel approach: procedures: instead of discussing the diagnostic categories of neurological syndromes, it focuses on the symptoms of common neurological presentations (especially in the emergency room or on the ward), and the diagnostic hypotheses that can be validated or rejected case by case as a result. Each chapter covers one of the main symptoms of emergencies in neurology – from transient consciousness disturbances to focal deficits, acute muscular disorders, respiratory insufficiency in neurological disorders, headaches, delirium, seizures and epileptic status, para-and tetraplegia, and head trauma, to acute functional disorders – and includes tables and figures to allow readers to gain a quick and easy, yet comprehensive overview of the topic. The book guides readers through various scenarios generated by the onset of symptoms, the clinical tools for differential diagnostics, and the principles of acute and post-acute phase therapy, managed by decision algorithms supported by the most recent scientific evidence.The resulting precedural profile – created through the collaboration of over 80 specialists in neurology or other disciplines – makes this text a valuable tool for neurologists, neurology residents and allied professionals in their daily clinical practice, as well as medical students.
Inbunden, Engelska, 2023
1 671 kr
Skickas inom 5-8 vardagar
This book is focused on a clinical-based diagnostic approach of autonomic dysfunctions, highlighting main diagnostic tools and pharmacological and non-pharmacological therapies available nowadays. The autonomic nervous system (ANS) is a subcomponent of the peripheral nervous system (PNS) and dysfunction of one or more subdivisions of the ANS, when accompanying other diseases, is linked to a worse prognosis of the latter. In some circumstances or when severe, dysfunction of ANS itself results in symptoms and disability. A myriad of factors can cause autonomic dysfunction and more than one can concur even in the same patient; due to the expansive nature of the ANS, patients can be affected by a wide range of conditions. Each chapter is characterized by a similar structure and is devoted to a different dysfunction. For each pathology, the book offers the essential information on mechanisms of action, treatments and outcomes. Written by experts in the research of these disorders, the volume addresses primarily Neurologists, but will be a useful tool also for Gastroenterologists, Ophthalmologists, Urologists, Cardiologists and Internal medicine specialists.
E-bok
Engelska, 20231 622 kr
Läs direkt efter köp
This book is focused on a clinical-based diagnostic approach of autonomic dysfunctions, highlighting main diagnostic tools and pharmacological and non-pharmacological therapies available nowadays.
The autonomic nervous system (ANS) is a subcomponent of the peripheral nervous system (PNS) and dysfunction of one or more subdivisions of the ANS, when accompanying other diseases, is linked to a worse prognosis of the latter. In some circumstances or when severe, dysfunction of ANS itself results in symptoms and disability. A myriad of factors can cause autonomic dysfunction and more than one can concur even in the same patient; due to the expansive nature of the ANS, patients can be affected by a wide range of conditions.
Each chapter is characterized by a similar structure and is devoted to a different dysfunction. For each pathology, the book offers the essential information on mechanisms of action, treatments and outcomes.
Written by experts in the research of these disorders, the volume addresses primarily Neurologists, but will be a useful tool also for Gastroenterologists, Ophthalmologists, Urologists, Cardiologists and Internal medicine specialists.
Häftad, Engelska, 2025
1 227 kr
Skickas inom 10-15 vardagar
This book is focused on a clinical-based diagnostic approach of autonomic dysfunctions, highlighting main diagnostic tools and pharmacological and non-pharmacological therapies available nowadays. The autonomic nervous system (ANS) is a subcomponent of the peripheral nervous system (PNS) and dysfunction of one or more subdivisions of the ANS, when accompanying other diseases, is linked to a worse prognosis of the latter. In some circumstances or when severe, dysfunction of ANS itself results in symptoms and disability. A myriad of factors can cause autonomic dysfunction and more than one can concur even in the same patient; due to the expansive nature of the ANS, patients can be affected by a wide range of conditions. Each chapter is characterized by a similar structure and is devoted to a different dysfunction. For each pathology, the book offers the essential information on mechanisms of action, treatments and outcomes. Written by experts in the research of these disorders, the volume addresses primarily Neurologists, but will be a useful tool also for Gastroenterologists, Ophthalmologists, Urologists, Cardiologists and Internal medicine specialists.
Inbunden, Engelska, 2027
2 463 kr
Skickas inom 11-20 vardagar
This book aims to provide adequate and updated clinical, diagnostic, and therapeutic references for the treatment of neurological emergencies. This volume describes the approach with decision-making algorithms that start from the symptom(s) for which the patient has accessed the emergency room.The volume provides practical tools for conducting a diagnostic and therapeutic path in urgent neurological conditions. Therefore, the volume clearly describes that a neurological emergency can be treated only after a clear-cut diagnosis has been carried out, and that this task is reserved to the neurologists.The book has also the important value to offer a complete overview on the most relevant advancement in the treatment of the neurological emergencies, contributing to the process of education of a modern neurologist that has the capacity to face the numerous and difficult problems of the diseases of the nervous system.