Howard E. Gendelman – författare

Neurological complications of progressive HIV-1 infection remain a common cause of morbidity even during widespread use of antiretroviral therapy (ART). Long-term resistance to ART, drug compliance, untoward drug side effects, a myriad of opportunistic infection, depression and other psychiatric disease manifestations, concomitant drug abuse, neuropathies, and an inability to clear viral reservoirs, explain, in large measure, disease progression and immune deterioration. These are associated with a number of psychiatric, muscle, nerve, infectious, as well as cognitive, behavioral, and motor disturbances seen in infected people. Fully updated from the previous two editions and replete with color images, The Neurology of AIDS, Third Edition covers each of these neurological complications and more with a focus on molecular and viral disease processes, cellular factors influencing viral replication therapeutic challenges, and the changing epidemiological patterns of disease. From basic science to clinical care, to epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the human immunodeficiency virus. It is an indispensable resource for students, resident physicians, practicing physicians, and for researchers and experts in the HIV/AIDS field.

Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a “blueprint” for  bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.

Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a “blueprint” for  bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.

Bridging neuroscience, immunology, and pharmacology, and bringing together the foremost authorities, Neuroimmune Pharmacology and Therapeutics, 3rd edition, is an invaluable reference and textbook. The text discusses the immunology of the nervous system. New chapters are offered on innate, humoral, and cellular immune responses (innate and adaptive immunity).  The additions join each component of the immune response in descriptions for how each affects nervous system function in both health and disease.  Next, discussions of neuropharmacology now include both drug development and delivery into brain subregions to optimize clinical responses. This edition features greatly expanded coverage of therapeutics.  The new extensions have blossomed into focused therapies engaging the immune system directly, deploying it for drug delivery, attracting the newly evolving field of genetics, vaccinations, and bioengineering, ultimately leading to improved therapeutic disease outcomes.   All of the revisions in this edition are designed to bring an early trainee together with a skilled clinical and translational scientist to discuss the state of the art in each part of the emerging field of immunity as it affects the nervous system during steady state and disease and how it can be harnessed for therapeutics and clinical benefit.