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Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided.
Features:
Highlights emerging scientific fields relevant to drug discovery such as the microbiome, nanotechnology, and cancer immunotherapy; and novel research tools such as CRISPR and DNA-encoded libraries
Case study detailing the discovery of the anti-cancer drug, lorlatinib
Venture capitalist commentary on trends and best practices in drug discovery and development
Comprehensive review of regulations and their impact on drug development, highlighting special populations, orphan drugs, and pharmaceutical compounding
Multidiscipline functioning of an Academic Research Enterprise, plus a chapter on Ethical Concerns in Research Contributions by 70+ experts from industry and academia specialists who developed and are practitioners of the science and business
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Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided.
Features:
Highlights emerging scientific fields relevant to drug discovery such as the microbiome, nanotechnology, and cancer immunotherapy; and novel research tools such as CRISPR and DNA-encoded libraries
Case study detailing the discovery of the anti-cancer drug, lorlatinib
Venture capitalist commentary on trends and best practices in drug discovery and development
Comprehensive review of regulations and their impact on drug development, highlighting special populations, orphan drugs, and pharmaceutical compounding
Multidiscipline functioning of an Academic Research Enterprise, plus a chapter on Ethical Concerns in Research Contributions by 70+ experts from industry and academia specialists who developed and are practitioners of the science and business
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On the morning of September 11, 2001, our world changed forevernot only in this country, but in every other country as well. There is undoubtedly no other single event occurring in our nations history that can compare with the impact felt that day. And for the brave men and women who made the ultimate sacrifice that September morning, their legacies will be carried by the family and friends who embraced them as sons, daughters, parents, and partners.
Sons of Valor, Parents of Faith shares the touching personal stories and interviews of the parents of New York City firefighters and one police detective killed on 9/11, and it takes us on their subsequent spiritual and emotional journeys. Although many of these men were young, they had already left a significant imprint on the world, and their parents now share their feelings about their grief in the aftermath of the tragedy. All the parents were brought together by the FDNY Counseling Services Unit to begin the healing process, where they learned how to heal after such a major disaster and loss. Parents should never bury their children; however, for the parents of the 343 lost New York City firefighters, September 11, 2001 changed the rules in so many different ways. Now in their own words, the faithful parents of these heroes share their sons bravery and sacrificeso that it will never be forgotten.
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