Jean-Michel Dubernard – författare

This new book, edited by internationally renowned specialists, also pools the experience of consultants from both Europe and the US. It is divided into three main sections: Organ Preservation, Organ Harvesting and Surgical Techniques. Many different organs are profiled, including the heart, kidneys, lungs, pancreas, intestine and bowel. The various aspects of preservation are discussed including cooling and preservation solutions, which are of special interest as researchers are actively exploring the composition of those solutions. Longer term preservation of the heart is still an unsolved problem and this is considered, as well as the pros and cons of organ donation from live or cadaveric donors. Fully referenced and illustrated with over 50 line drawings, Organ Preservation and Transplant Surgery will be of particular interest to those involved in the often complex surgery of organ harvesting or trainees in transplantation surgery. It gives clear accounts of techniques and a detailed update in the underlying science that determines and currently limits organ storage. It will also prove invaluable to the younger researcher who needs a clearer understanding of the scientific basis of organ preservation and the clinical need for better organ preservation.

This new book, edited by internationally renowned specialists, also pools the experience of consultants from both Europe and the US. It is divided into three main sections: Organ Preservation, Organ Harvesting and Surgical Techniques. Many different organs are profiled, including the heart, kidneys, lungs, pancreas, intestine and bowel. The various aspects of preservation are discussed including cooling and preservation solutions, which are of special interest as researchers are actively exploring the composition of those solutions. Longer term preservation of the heart is still an unsolved problem and this is considered, as well as the pros and cons of organ donation from live or cadaveric donors. Fully referenced and illustrated with over 50 line drawings, Organ Preservation and Transplant Surgery will be of particular interest to those involved in the often complex surgery of organ harvesting or trainees in transplantation surgery. It gives clear accounts of techniques and a detailed update in the underlying science that determines and currently limits organ storage. It will also prove invaluable to the younger researcher who needs a clearer understanding of the scientific basis of organ preservation and the clinical need for better organ preservation.

This new book, edited by internationally renowned specialists, also pools the experience of consultants from both Europe and the US. It is divided into three main sections: Organ Preservation, Organ Harvesting and Surgical Techniques. Many different organs are profiled, including the heart, kidneys, lungs, pancreas, intestine and bowel. The various aspects of preservation are discussed including cooling and preservation solutions, which are of special interest as researchers are actively exploring the composition of those solutions. Longer term preservation of the heart is still an unsolved problem and this is considered, as well as the pros and cons of organ donation from live or cadaveric donors. Fully referenced and illustrated with over 50 line drawings, Organ Preservation and Transplant Surgery will be of particular interest to those involved in the often complex surgery of organ harvesting or trainees in transplantation surgery. It gives clear accounts of techniques and a detailed update in the underlying science that determines and currently limits organ storage. It will also prove invaluable to the younger researcher who needs a clearer understanding of the scientific basis of organ preservation and the clinical need for better organ preservation.

The first textbook of its kind dealing with composite tissue allograft and allograft transplantation, provides an excellent overview on the subject. It provides a clear description of the current status of the transplant of every composite tissue allograft already performed and others which are still at the basic experimental level.The editors of the book, who also contribute chapters in their expertise, are world renowned surgeons. This book opens with an introductory chapter on the history of this type of transplantation and then details the clinical experience in each graft such as hand, larynx, face, uterus and the related histopathology, immunosuppression and immunomodulation.A multidisciplinary and comprehensive presentation of the various aspects of this new area of transplantation will allow the reader to understand the complexity and the challenges of composite tissue transplantation. A number of important topics are analyzed and discussed in detail, such as the ethical, medicolegal, psychological and immunological implications. New rehabilitation techniques and strategies, together with innovative tools for the functional evaluation of the transplanted parts, are highlighted. A section on the experimental work underlines what lies ahead of us.Sample Chapter(s)

Transplanting hands -- a model of composite tissue grafting -- began in Lyons in November 1998 with the transplant of one hand and then, in January 2000, of two, both with the support of the Mérieux Foundation. Advances in immunosuppression made possible some unusual transplants of tissue, such as bones, knee-joints, femurs and larynx. From these stemmed the first attempts to transplant hands. This book looks at the long-term results of reattaching hands that have been accidentally amputated. It reviews all the problems -- technical, immunological, nervous, functional and psychological -- that surgeons encountered during and after the transplants. Surgeons, transplant experts, immunologists, dermatologists, psychiatrists, neurophysiologists, physiotherapists and re-education experts will also find here answers to their ethical and legal questions about removing tissue from donors, as well as information about composite tissue grafts in plastic and reconstructive surgery.

Hand transplantation was the dream of humanity until 1998, when a group of international surgeons gathered in Lyon performed the first of many hand transplantations carried out since then. This book presents the global international experimental and clinical experience on limb transplantation and other composite tissue allografts. It represents the most complete and comprehensive review of all aspects of this innovative and groundbreaking procedure. They range from the experimental basis of hand transplantation, to surgical techniques, to immunology and antirejection drug strategies, to the presentation of the current functional results and future directions, including the possibility to introduce face and uterus transplantation to the clinical practice. This book represents a milestone in the medical literature and is a great asset for every scientific library.