Jeffrey H. Miner – författare
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2 produkter
2 produkter
2 194 kr
Skickas inom 7-10 vardagar
Basement Membranes focuses on specialized extracellular matrices that provide the scaffolds used and required by cells to organize themselves into tissues and organs. As basement membranes have been shown to be defective in numerous genetic and acquired diseases and to contribute to the microenvironment of both tumor cells and stem cells, this book presents a view of specific basement membrane components and their roles in development and disease, all written and commented on in chapters written by leaders in the basement membrane field. Written by leading experts in the basement membrane field Contains original material, both textual and illustrative, that should become a very relevant reference material Presents material in a very comprehensive manner Ideal for both researchers in the field and general readers who will find relevant and up-to-date information
Del 15 - Advances in Developmental Biology
Extracellular Matrix in Development and Disease
Inbunden, Engelska, 2006
1 547 kr
Skickas inom 7-10 vardagar
Extracellular matrix proteins are serious, common human diseases that are caused by mutations in genes that encode these proteins. This has spurred a great number of researchers to study the extracellular matrix, sometimes by choice and sometimes by necessity. Much progress has been made in the last decade towards understanding what matrix proteins do and how cells interact with and respond to them. Volume 15 is a compilation of reviews by experts in their respective fields. The chapters in this book address the biology of a broad spectrum of extracellular matrix molecules and their functions in development and disease. This book has been designed to focus on a diverse subset of matrix proteins that have been shown to be important for development, function, and disease. The book therefore both presents a broad view of the field and provides crucial details about some of the best-studied matrix molecules.* Written by leaders in the field* Discusses the potential of matrix components to be used as therapeutic tools for the treatment and prevention of cancer* Offers a section on integrin signaling and the development of the central nervous system, detailing the migration of neurons and the glia* Covers a diverse array of molecules such as laminins, collagens, heparan sulfate proteoglycans, integrins, and more