Jens Nielsen – författare & böcker

Metabolic Engineering

Principles and Methodologies

AvJens Nielsen,Aristos A. Aristidoum. fl.

E-bok

PDF, Engelska, 1998

2 037 kr

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Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field''s novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes.Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems.- Demonstrates metabolic engineering in action with numerous examples of pathway modification- Includes methods for identifying key enzymes in metabolic networks- Contains a comprehensive review of metabolic biochemistry- Discusses metabolic regulation at the gene, enzyme, operon, and cell levels- Explains concepts of stoichiometry, kinetics, and thermodynamics of metabolic pathways- Minimizes mathematical complexity- Links to a Web page to communicate updates of the software code and homework problems

Fermentation Microbiology and Biotechnology, Fourth Edition

AvE. M. T. El-Mansi,Jens Nielsenm. fl.

Häftad, Engelska, 2020

797 kr

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Fermentation Microbiology and Biotechnology, 4th Edition explores and illustrates the broad array of metabolic pathways employed for the production of primary and secondary metabolites, as well as biopharmaceuticals. This updated and expanded edition addresses the whole spectrum of fermentation biotechnology, from fermentation kinetics and dynamics to protein and co-factor engineering. It also sheds light on the new strategies employed by industrialist for increasing tolerance and endurance of microorganisms to the accumulation of toxic wastes in microbial-cell factories. The new edition builds upon the fine pedigree of its earlier predecessors and extends the spectrum of the book to reflect the multidisciplinary and buoyant nature of this subject area.Key Features Covers the whole spectrum of the field from fermentation kinetics to control of fermentation and protein engineering. Includes case studies specifically designed to illustrate industrial applications and current state-of-the-art technologies. Presents the contributions of eminent international academics and industrial experts. Offers new chapters addressing: The prospects and the role of bio-fuels refineries, Control of metabolic efflux to product formation in microbial-cell factories and Improving tolerance of microorganisms to toxic byproduct accumulation in the fermentation vessel.

Fermentation Microbiology and Biotechnology, Fourth Edition

AvRoss P. Carlson,David Mousdalem. fl.

E-bok

Engelska, 2018

891 kr

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Fermentation Microbiology and Biotechnology, 4th Edition explores and illustrates the broad array of metabolic pathways employed for the production of primary and secondary metabolites, as well as biopharmaceuticals. This updated and expanded edition addresses the whole spectrum of fermentation biotechnology, from fermentation kinetics and dynamics to protein and co-factor engineering. It also sheds light on the new strategies employed by industrialist for increasing tolerance and endurance of microorganisms to the accumulation of toxic wastes in microbial-cell factories. The new edition builds upon the fine pedigree of its earlier predecessors and extends the spectrum of the book to reflect the multidisciplinary and buoyant nature of this subject area.

Key Features

Covers the whole spectrum of the field from fermentation kinetics to control of fermentation and protein engineering.

Includes case studies specifically designed to illustrate industrial applications and current state-of-the-art technologies.

Presents the contributions of eminent international academics and industrial experts.

Offers new chapters addressing:

The prospects and the role of bio-fuels refineries,

Control of metabolic efflux to product formation in microbial-cell factories and

Improving tolerance of microorganisms to toxic byproduct accumulation in the fermentation vessel.

Fermentation Microbiology and Biotechnology, Fourth Edition

AvRoss P. Carlson,David Mousdalem. fl.

E-bok

PDF, Engelska, 2018

860 kr

Läs direkt efter köp

Fermentation Microbiology and Biotechnology, 4th Edition explores and illustrates the broad array of metabolic pathways employed for the production of primary and secondary metabolites, as well as biopharmaceuticals. This updated and expanded edition addresses the whole spectrum of fermentation biotechnology, from fermentation kinetics and dynamics to protein and co-factor engineering. It also sheds light on the new strategies employed by industrialist for increasing tolerance and endurance of microorganisms to the accumulation of toxic wastes in microbial-cell factories. The new edition builds upon the fine pedigree of its earlier predecessors and extends the spectrum of the book to reflect the multidisciplinary and buoyant nature of this subject area.

Key Features

Covers the whole spectrum of the field from fermentation kinetics to control of fermentation and protein engineering.

Includes case studies specifically designed to illustrate industrial applications and current state-of-the-art technologies.

Presents the contributions of eminent international academics and industrial experts.

Offers new chapters addressing:

The prospects and the role of bio-fuels refineries,

Control of metabolic efflux to product formation in microbial-cell factories and

Improving tolerance of microorganisms to toxic byproduct accumulation in the fermentation vessel.

Metabolome Analysis

An Introduction

AvUte Roessner-Tunali,Michael A. E. Hansenm. fl.

E-bok

PDF, Engelska, 2007

1 566 kr

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Providing information on the main approaches for the analysis of metabolites, this textbook: Covers basic methodologies in sample preparation and separation techniques, as well as the most recent techniques of mass spectrometry. Differentiates between primary and secondary metabolites. Includes four chapters discussing successful metabolome studies of different organisms. Highlights the analytical challenges of studying metabolites. Illustrates applications of metabolome analysis through the use of case studies.

Del 24 - Wiley Series on Mass Spectrometry

Metabolome Analysis

An Introduction

AvSilas G. Villas-Boas,Jens Nielsenm. fl.

Inbunden, Engelska, 2007

1 364 kr

Skickas inom 5-8 vardagar

Providing information on the main approaches for the analysis of metabolites, this textbook: Covers basic methodologies in sample preparation and separation techniques, as well as the most recent techniques of mass spectrometry.Differentiates between primary and secondary metabolites.Includes four chapters discussing successful metabolome studies of different organisms.Highlights the analytical challenges of studying metabolites.Illustrates applications of metabolome analysis through the use of case studies.

Fermentation Microbiology and Biotechnology, Fourth Edition

AvE. M. T. El-Mansi,Jens Nielsenm. fl.

Inbunden, Engelska, 2019

3 682 kr

Skickas inom 10-15 vardagar

Fermentation Microbiology and Biotechnology, 4th Edition explores and illustrates the broad array of metabolic pathways employed for the production of primary and secondary metabolites, as well as biopharmaceuticals. This updated and expanded edition addresses the whole spectrum of fermentation biotechnology, from fermentation kinetics and dynamics to protein and co-factor engineering. It also sheds light on the new strategies employed by industrialist for increasing tolerance and endurance of microorganisms to the accumulation of toxic wastes in microbial-cell factories. The new edition builds upon the fine pedigree of its earlier predecessors and extends the spectrum of the book to reflect the multidisciplinary and buoyant nature of this subject area.Key Features Covers the whole spectrum of the field from fermentation kinetics to control of fermentation and protein engineering. Includes case studies specifically designed to illustrate industrial applications and current state-of-the-art technologies. Presents the contributions of eminent international academics and industrial experts. Offers new chapters addressing: The prospects and the role of bio-fuels refineries, Control of metabolic efflux to product formation in microbial-cell factories and Improving tolerance of microorganisms to toxic byproduct accumulation in the fermentation vessel.

Bioreaction Engineering Principles

AvJohn Villadsen,Jens Nielsenm. fl.

Inbunden, Engelska, 2011

1 084 kr

Skickas inom 10-15 vardagar

The present text is a complete revision of the 2nd edition from 2003 of the book with the same title. In recognition of the fast pace at which biotechnology is moving we have rewritten several chapters to include new scientific progress in the field from 2000 to 2010. More important we have changed the focus of the book to support its use, not only in universities, but also as a guide to design new processes and equipment in the bio-industry. A new chapter has been included on the prospects of the bio-refinery to replace many of the oil- and gas based processes for production of especially bulk chemicals. This chapter also serves to make students in Chemical Engineering and in the Bio-Sciences enthusiastic about the whole research field. As in previous editions we hope that the book can be used as textbook for classes, even at the undergraduate level, where chemical engineering students come to work side by side with students from biochemistry and microbiology. To help the chemical engineering students Chapter 1 includes a brief review of the most important parts of microbial metabolism. In our opinion this review is sufficient to understand microbial physiology at a sufficiently high level to profit from the rest of the book. Likewise the bio-students will not be overwhelmed by mathematics, but since the objective of the book is to teach quantitative process analysis and process design at a hands-on level some mathematics and model analysis is needed. We hope that the about 100 detailed examples and text notes, together with many instructive problems will be sufficient to illustrate how model analysis is used, also in Bio-reaction Engineering.

Bioreaction Engineering Principles

AvGunnar Liden,Jens Nielsenm. fl.

E-bok

PDF, Engelska, 2011

1 367 kr

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The present text is a complete revision of the 2nd edition from 2003 of the book with the same title. In recognition of the fast pace at which biotechnology is moving we have rewritten several chapters to include new scientific progress in the field from 2000 to 2010. More important we have changed the focus of the book to support its use, not only in universities, but also as a guide to design new processes and equipment in the bio-industry. A new chapter has been included on the prospects of the bio-refinery to replace many of the oil- and gas based processes for production of especially bulk chemicals. This chapter also serves to make students in Chemical Engineering and in the Bio-Sciences enthusiastic about the whole research field. As in previous editions we hope that the book can be used as textbook for classes, even at the undergraduate level, where chemical engineering students come to work side by side with students from biochemistry and microbiology. To help the chemical engineering students Chapter 1 includes a brief review of the most important parts of microbial metabolism. In our opinion this review is sufficient to understand microbial physiology at a sufficiently high level to profit from the rest of the book. Likewise the bio-students will not be overwhelmed by mathematics, but since the objective of the book is to teach quantitative process analysis and process design at a hands-on level some mathematics and model analysis is needed. We hope that the about 100 detailed examples and text notes, together with many instructive problems will be sufficient to illustrate how model analysis is used, also in Bio-reaction Engineering.

Bioreaction Engineering Principles

Second Edition

AvGunnar Liden,John Villadsenm. fl.

E-bok

PDF, Engelska, 2012

1 140 kr

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This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990''s will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.

Bioreaction Engineering Principles

AvJohn Villadsen,Jens Nielsen

E-bok

PDF, Engelska, 2013

1 459 kr

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Integrating recent research on the physiology and modelling of bioreactions and bioreactors, the authors present a comprehensive, unified introduction to the principles and practices of the field. The work features nearly 100 detailed design examples and problems, many of which are suitable for hands-on demonstrations on a personal computer or for expanded research. The text will serve as a highly instructive guide for students in bioengineering and biotechnology, as well as biochemical, chemical, and environmental engineering.

Bioreaction Engineering Principles

AvJens Nielsen,John Villadsen

Häftad, Engelska, 2013

1 116 kr

Skickas inom 10-15 vardagar

Integrating recent research on the physiology and modelling of bioreactions and bioreactors, the authors present a comprehensive, unified introduction to the principles and practices of the field. The work features nearly 100 detailed design examples and problems, many of which are suitable for hands-on demonstrations on a personal computer or for expanded research. The text will serve as a highly instructive guide for students in bioengineering and biotechnology, as well as biochemical, chemical, and environmental engineering.

Bioreaction Engineering Principles

AvJohn Villadsen,Jens Nielsenm. fl.

Häftad, Engelska, 2014

1 084 kr

Skickas inom 10-15 vardagar

The present text is a complete revision of the 2nd edition from 2003 of the book with the same title. In recognition of the fast pace at which biotechnology is moving we have rewritten several chapters to include new scientific progress in the field from 2000 to 2010. More important we have changed the focus of the book to support its use, not only in universities, but also as a guide to design new processes and equipment in the bio-industry. A new chapter has been included on the prospects of the bio-refinery to replace many of the oil- and gas based processes for production of especially bulk chemicals. This chapter also serves to make students in Chemical Engineering and in the Bio-Sciences enthusiastic about the whole research field. As in previous editions we hope that the book can be used as textbook for classes, even at the undergraduate level, where chemical engineering students come to work side by side with students from biochemistry and microbiology. To help the chemical engineering students Chapter 1 includes a brief review of the most important parts of microbial metabolism. In our opinion this review is sufficient to understand microbial physiology at a sufficiently high level to profit from the rest of the book. Likewise the bio-students will not be overwhelmed by mathematics, but since the objective of the book is to teach quantitative process analysis and process design at a hands-on level some mathematics and model analysis is needed. We hope that the about 100 detailed examples and text notes, together with many instructive problems will be sufficient to illustrate how model analysis is used, also in Bio-reaction Engineering.

Advances in Dynamics of Vehicles on Roads and Tracks

Proceedings of the 26th Symposium of the International Association of Vehicle System Dynamics, IAVSD 2019, August 12-16, 2019, Gothenburg, Sweden

Springer Nature Switzerland AG

2020

4 200 kr

Skickas inom 10-15 vardagar

This book gathers together papers presented at the 26th IAVSD Symposium on Dynamics of Vehicles on Roads and Tracks, held on August 12 – 16, 2019, at the Lindholmen Conference Centre in Gothenburg, Sweden. It covers cutting-edge issues related to vehicle systems, including vehicle design, condition monitoring, wheel and rail contact, automated driving systems, suspension and ride analysis, and many more topics. Written by researchers and practitioners, the book offers a timely reference guide to the field of vehicle systems dynamics, and a source of inspiration for future research and collaborations.

Advances in Dynamics of Vehicles on Roads and Tracks

Proceedings of the 26th Symposium of the International Association of Vehicle System Dynamics, IAVSD 2019, August 12-16, 2019, Gothenburg, Sweden

AvAngela Hillemyr,Jens Nielsenm. fl.

E-bok

Engelska, 2020

4 422 kr

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This book gathers together papers presented at the 26th IAVSD Symposium on Dynamics of Vehicles on Roads and Tracks, held on August 12 – 16, 2019, at the Lindholmen Conference Centre in Gothenburg, Sweden. It covers cutting-edge issues related to vehicle systems, including vehicle design, condition monitoring, wheel and rail contact, automated driving systems, suspension and ride analysis, and many more topics. Written by researchers and practitioners, the book offers a timely reference guide to the field of vehicle systems dynamics, and a source of inspiration for future research and collaborations.

Advances in Dynamics of Vehicles on Roads and Tracks

Proceedings of the 26th Symposium of the International Association of Vehicle System Dynamics, IAVSD 2019, August 12-16, 2019, Gothenburg, Sweden

Springer Nature Switzerland AG

2021

4 200 kr

Skickas inom 10-15 vardagar

This book gathers together papers presented at the 26th IAVSD Symposium on Dynamics of Vehicles on Roads and Tracks, held on August 12 – 16, 2019, at the Lindholmen Conference Centre in Gothenburg, Sweden. It covers cutting-edge issues related to vehicle systems, including vehicle design, condition monitoring, wheel and rail contact, automated driving systems, suspension and ride analysis, and many more topics. Written by researchers and practitioners, the book offers a timely reference guide to the field of vehicle systems dynamics, and a source of inspiration for future research and collaborations.

Hau de Katt de Schwanz aff!: Rummelpottlaufen ... viel mehr als eine Silvestertradition

AvMarco Boehm,Jens Nielsen

Häftad, Tyska, 2023

176 kr

Skickas inom 3-6 vardagar

Hau de Katt de Schwanz aff!

Rummelpottlaufen … viel mehr als eine Silvestertradition

AvJens Nielsen,Marco Boehm

E-bok

Tyska, 2023

89 kr

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Dieses Buch ist eine überraschende Spurensuche rund um das Thema Rummelpottlaufen. Dabei wird der Herkunft dieser Tradition auf den Grund gegangen. Es ist die Suche nach den faszinierenden, noch vorhandenen Merkmalen des alten Brauchtums.Hinzu kommen Rezepte und Baupläne, Anleitungen und Beschreibungen, die alle in einem appetitanregenden Zusammenhang mit dem sogenannten Rummelpott und seiner Tradition stehen. Während der Neuentdeckung kulinarischer, musikalischer, volkskundlicher, handwerklicher und literarischer Leckerbissen, kann dabei so manches Überraschende neu aufgespürt oder wieder hervorgeholt und so dem Vergessen entrissen werden.

Systems Biology

AvStefan Hohmann,Jens Nielsen

E-bok

PDF, Engelska, 2017

2 138 kr

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Comprehensive coverage of the many different aspects of systems biology, resulting in an excellent overview of the experimental and computational approaches currently in use to study biological systems. Each chapter represents a valuable introduction to one specific branch of systems biology, while also including the current state of the art and pointers to future directions. Following different methods for the integrative analysis of omics data, the book goes on to describe techniques that allow for the direct quantification of carbon fluxes in large metabolic networks, including the use of 13C labelled substrates and genome-scale metabolic models. The latter is explained on the basis of the model organism Escherichia coli as well as the human metabolism. Subsequently, the authors deal with the application of such techniques to human health and cell factory engineering, with a focus on recent progress in building genome-scale models and regulatory networks. They highlight the importance of such information for specific biological processes, including the ageing of cells, the immune system and organogenesis. The book concludes with a summary of recent advances in genome editing, which have allowed for precise genetic modifications, even with the dynamic control of gene expression. This is part of the Advances Biotechnology series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question.

Systems Biology

AvStefan Hohmann,Jens Nielsen

E-bok

Engelska, 2017

2 215 kr

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Comprehensive coverage of the many different aspects of systems biology, resulting in an excellent overview of the experimental and computational approaches currently in use to study biological systems. Each chapter represents a valuable introduction to one specific branch of systems biology, while also including the current state of the art and pointers to future directions. Following different methods for the integrative analysis of omics data, the book goes on to describe techniques that allow for the direct quantification of carbon fluxes in large metabolic networks, including the use of 13C labelled substrates and genome-scale metabolic models. The latter is explained on the basis of the model organism Escherichia coli as well as the human metabolism. Subsequently, the authors deal with the application of such techniques to human health and cell factory engineering, with a focus on recent progress in building genome-scale models and regulatory networks. They highlight the importance of such information for specific biological processes, including the ageing of cells, the immune system and organogenesis. The book concludes with a summary of recent advances in genome editing, which have allowed for precise genetic modifications, even with the dynamic control of gene expression. This is part of the Advances Biotechnology series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question.

Metabolic Engineering

Concepts and Applications

AvGregory Stephanopoulos,Jens Nielsenm. fl.

E-bok

PDF, Engelska, 2021

4 504 kr

Läs direkt efter köp

Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field

Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation.

Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya.

The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about:

Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more

Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It''s comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.

Metabolic Engineering

Concepts and Applications

AvGregory Stephanopoulos,Jens Nielsenm. fl.

E-bok

Engelska, 2021

4 504 kr

Läs direkt efter köp

Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field

Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation.

Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya.

The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about:

Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more

Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It''s comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.

Biotechnology for the Future

AvJens Nielsen

Inbunden, Engelska, 2005

2 161 kr

Skickas inom 10-15 vardagar

Metabolic Engineering

AvJens Nielsen

Inbunden, Engelska, 2001

2 161 kr

Skickas inom 10-15 vardagar

Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.

Metabolic Engineering

AvJens Nielsen

E-bok

PDF, Engelska, 2003

2 840 kr

Läs direkt efter köp

Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.

Del 18 - Topics in Current Genetics

Metabolomics

A Powerful Tool in Systems Biology

AvJens Nielsen,Michael C. Jewett

Inbunden, Engelska, 2007

2 700 kr

Skickas inom 10-15 vardagar

The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated with a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the metabolic network impact cellular behavior, metabolomics has emerged as an important complementary technology to the cell-wide measurements of mRNA, proteins, fluxes, and interactions (e.g., protein-DNA). Metabolomics is already a powerful tool in drug discovery and development and in metabolic engineering. While maintaining these strengths, the field promises to play a heightened role in systems biology research, which is transforming the practice of medicine and our ability to engineer living organisms. This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.

Metabolomics

A Powerful Tool in Systems Biology

AvMichael C. Jewett,Jens Nielsen

E-bok

PDF, Engelska, 2007

3 351 kr

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The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated with a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the metabolic network impact cellular behavior, metabolomics has emerged as an important complementary technology to the cell-wide measurements of mRNA, proteins, fluxes, and interactions (e.g., protein-DNA). Metabolomics is already a powerful tool in drug discovery and development and in metabolic engineering. While maintaining these strengths, the field promises to play a heightened role in systems biology research, which is transforming the practice of medicine and our ability to engineer living organisms.

This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.

Del 100 - Advances in Biochemical Engineering/Biotechnology

Biotechnology for the Future

AvJens Nielsen

Häftad, Engelska, 2010

2 161 kr

Skickas inom 10-15 vardagar

Del 73 - Advances in Biochemical Engineering/Biotechnology

Metabolic Engineering

AvJens Nielsen

Häftad, Engelska, 2010

2 161 kr

Skickas inom 10-15 vardagar

Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.

Del 18 - Topics in Current Genetics

Metabolomics

A Powerful Tool in Systems Biology

AvJens Nielsen,Michael C. Jewett

Häftad, Engelska, 2010

2 700 kr

Skickas inom 10-15 vardagar

The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated with a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the metabolic network impact cellular behavior, metabolomics has emerged as an important complementary technology to the cell-wide measurements of mRNA, proteins, fluxes, and interactions (e.g., protein-DNA). Metabolomics is already a powerful tool in drug discovery and development and in metabolic engineering. While maintaining these strengths, the field promises to play a heightened role in systems biology research, which is transforming the practice of medicine and our ability to engineer living organisms. This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.