Johann Rastetter – författare

This 6th edition of the atlas has integrated the 2001 WHO classification and made use of figures and descriptions to document recently described types of leukemia and lymphoma. The latter include leukemias of dendritic cells, rare lymphomas and persistent polyclonal B lymphocytosis, which takes a special place in the classification.The volume covers all the microscopic methods in hematology that form the basis of diagnosis as well as the results of modern immunologic, cytogenetic and molecular-genetic investigation. Special emphasis is placed on the cytogenetic and molecular-genetic characterization of biological entities that might form the basis for innovative therapies.Normal results and pathological findings are compared, and the various findings made during therapy are depicted. All in all the Atlas of Clinical Hematology represents a complete and helpful reference work which should be present in every hematologic and oncologic department as well as in clinical laboratories for online diagnostics and scientific research.

This 6th edition of the atlas has integrated the 2001 WHO classification and made use of figures and descriptions to document recently described types of leukemia and lymphoma. The latter include leukemias of dendritic cells, rare lymphomas and persistent polyclonal B lymphocytosis, which takes a special place in the classification.The volume covers all the microscopic methods in hematology that form the basis of diagnosis as well as the results of modern immunologic, cytogenetic and molecular-genetic investigation. Special emphasis is placed on the cytogenetic and molecular-genetic characterization of biological entities that might form the basis for innovative therapies.Normal results and pathological findings are compared, and the various findings made during therapy are depicted. All in all the Atlas of Clinical Hematology represents a complete and helpful reference work which should be present in every hematologic and oncologic department as well as in clinical laboratories for online diagnostics and scientific research.

Der Atlas zeichnet sich durch eine sehr weite inhaltlicheund methodische Auswahl aus. Auf diese Weise ist einStandardwerk entstanden, das es dem zytologischen Neulinggestattet, sich ohne Schwierigkeiten in die h{matologischeMorphologie einzuarbeiten, dar}ber hinaus aber auch demh{matologisch Erfahrenen mancherlei neue Anregungen zu gebenvermag.

Hematology, the study of the blood and its disorders, has existed as a science for about one hundred years. During that period it has remained true to its goals. Despite many advances in the submicroscopic and biochemical realm, hematology has clung to its basic postulate that the majority of blood disorders are expressed in morphologically distinct cell changes. Even modern hematology relies largely on the morphologic examination of cells, and the microscope con­ tinues to be its main diagnostic tool. Today we may describe hematology as the only morphologically oriented clinical science. It owes its existence chiefly to the development of staining methods which make it possible to assign mor­ phologic structures to specific cellular functions and thus to specific pathologic states. The first step in this direction was the brilliant discovery of panoptic stains in the early part of this century by Pappenheim, Wright, and others. This was followed in the 1950s and 1960s by the development of numerous cytochemical procedures for the differentiation of diverse biochemical reactions and cell types. In the last decade, immunologic methods have been employed to identify cell type-specific antigens as a means of classifying lymphoid and other cells more precisely and more objectively. This has aided in the differentia­ tion of many important hematologic diseases. In this fourth edition of the Atlas of Clinical Hematology, we have attempted to update the text and bring it in line with recent developments.