John W. Gofman – författare

Advances in Biological and Medical Physics, Volume 13 covers articles on the advances in biological and medical physics. The book presents papers on the solid-state physics of electron and ion transport in biology; on microelectrophoretic studies on the surface chemistry of erythrocytes; and on a specific common chromosomal pathway for the origin of human malignancy, including an evaluation of long-term human hazards of potential environmental carcinogens. The text then discusses the instantaneous radiation levels at different altitudes and latitudes; the accumulated radiation exposures to crew members and passengers; and the resulting radiation burden to the entire population. The theory and practical application of the selective destruction of cell organelles by laser beam, as well as some aspects of radiation effects on cell membranes are also considered. The book further tackles the effects of radiation on artificial lipid membranes; the role of bacterial membranes in radiosensitization; and the effects of ionizing radiation on lysosomes and other intracellular membranes. The text also describes the high oxygen effect for the release of enzymes from isolated mammalian lysosomes after treatment with ionizing radiation; as well as the effects of ultraviolet and visible light on nerve fibers and changes in optical properties during nervous activity. The effects of ultraviolet radiation on isolated nerve fibers are also looked into. Biological and medical physicists and students taking these courses will find the book invaluable.

Advances in Biological and Medical Physics, Volume 15 covers papers on the productive applications of physical science in biology and medicine. The book presents articles dealing with the geometric influence of bone matrix on the differentiation of fibroblasts and information on human repetitious DNA; the complexity of the human genome; and possible directions for future research. The text then describes the problem of biological time. The microcirculatory basis of fluid exchange is also considered. The book concludes with articles dealing with the possibilities for electron microscopy and diffraction of wet, unstained and unfixed biological material, as well as with the metabolic events in localized compartments of the living cell carried out through the use of rapid microspectrofluorometry. Biological and medical physicists and students taking these courses will find the book invaluable.

Advances in Biological and Medical Physics, Volume 16 covers articles about advances in biological and medical physics. The book presents articles about studies on spontaneous bioelectric activity of nerve cells in cultures and on means and methods for processing of physiological signals with emphasis on EEG analysis. The text also includes articles on dissipative structures and biological order; on spatial and temporal organization in the Zhabotinsky reaction; as well as on chemical topology and reaction dynamics. The perspectives on thermodynamics and the origin of life; pattern formation in a model for cooperative membrane carrier transport; as well as an enzyme membrane oscillator are also considered. The book further describes articles about synthetic membranes and living cells, membrane structure and passive flows, and energetics of active transport. The text then discusses the isolation and characterization of different molecular forms of acetylcholinesterase and the relationship of the enzyme to the membrane; as well as the chemical control of bioelectric currents. The traditional conflict between physics and metaphysics; human and scientific concepts of time; the relation of the sciences to human and religious values; and moiré patterns in science and art are also encompassed. The book concludes by providing summary remarks and personal recollections of Aharon Katchalsky and a description of Aharon Katzir as a scientist and humanist. Biological and medical physicists will find the book invaluable.

Advances in Biological and Medical Physics, Volume 17 covers articles on the advances in biological and medical physics. The book presents articles on energy transfer dynamics; the molecular mechanism of DNA repair after ionizing radiation; and mechanisms of prereplication repair of DNA breaks in gamma-irradiated E. coli cells. The text then describes articles about damages to DNA that result in neoplastic transformation; the nature of radiation and chemically-induced lesions and the role of cellular mechanisms in cell survival and mutagenesis; as well as the nature of the target in the biological action of ionizing radiation. The gated detection and analysis of nanosecond pulse excitation and the time-profile multicomponent analysis using nonintrusive mass spectrometry are also considered. The book further tackles the technique of acoustic microscopy in biophysics and the use of electron spin echo spectroscopy in the study of biological structure and function. The text also describes radiation as an oncogen and as a cocarcinogen at the cellular level and speculates on some possible molecular and cellular mechanisms of radiocarcinogenesis. Biological and medical physicists, biologists, and chemists will find the book invaluable.

Advances in Biological and Medical Physics, Volume 12 covers the significant progress in various aspects of biology and medical physics. This volume is composed of 16 chapters. The opening chapters deal with the principles and application of freeze-etching technique and scanning electron microscopy. The succeeding chapters review the development rudimentary model of the chromosome, the mechanisms involving large number of steps to kinetic studies of multisubstrate enzyme systems, and some biophysical approaches to evaluate radiation effects and their repair. These topics are followed by discussions the origin of the observed fluorescence and phosphorescence spectra of DNA, as well as some aspects of energy transfer that apply to DNA and other polynucleotides. Other chapters explore the processes of cellular repair, cell''s radiation sensivity, bacterial photoreactivation of mutation, and the genetic control of DNA repair and genetic recombination. The final chapters consider the mechanism of mutation suppression in yeast, the role of cytoplasm in radiobiology, and the different random factors governing the dose-effect relation. This book is of value to biologists, medical physicists, and medical practitioners.

Advances in Biological and Medical Physics, Volume 14 focuses on the application of physics to biology and medicine. The topics covered in this book include mechanical, biochemical, and architectural features of surgical repair; structure of normal and pathologic erythrocytes; and cytology automation. The analysis of reported physiologic effects of microwave radiation; spectroscopic methods in biology, with application to neurophysiology; and transmission of pictorial information through the skin are also deliberated in this text. This compilation likewise discusses the apparatus for tactile image projection, cutaneous stimulation, and neural factors. This publication is a good reference for students and individuals researching on biological and medical physics.

Advances in Biological and Medical Physics, Volume 10 focuses on the application of physics to biology and medicine. The topics covered in this book include effects of ionizing radiation on the nervous system; use of short-lived nuclides in medical research; and biological effects of laser radiation. The tracer techniques for the study of bone metabolism in man; elastic reservoir theories of the human circulation with applications to clinical medicine and to computer analysis of the circulation; and implantable cardiac pacemakers are also deliberated in this text. This publication is a good source for students and researchers conducting work on biological and medical physics.

Advances in Biological and Medical Physics provides an overview of the state of knowledge in biological and medical physics. The book contains seven chapters and begins with a discussion of the kinetics of cellular proliferation. This is followed by separate chapters on energy distribution in the absorption of radiation; polymorphic transitions of lipids and their possible role in the structure and function of membranes; and chemical interrelationships between the major classes of serum lipoproteins and statistical interrelationships between the serum concentrations of major classes of lipoproteins. Subsequent chapters deal with applications of thermodynamics and the theory of mechanics to the study of mechanisms responsible for material transfer through the membranes of living cells; the role of the swimbladder rete of fish in inert gas and oxygen secretion; and zone centrifugation techniques.