Jorge Morales-Montor – författare

Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives provides high level knowledge on detailed mechanisms of actions and biological interactions of different immune drugs, with an aim of offering researchers and clinicians cutting-edge therapies to overcome drug resistance. The book explains the latest immunotherapies for different types of cancer, helping users carry out research projects or create alternatives for drug development in the pharmaceutical industry. Topics discussed include the relationship between immunotherapy and macrophages, immune checkpoints in different types of cancer, immune cocktails in solid tumors, and immune-phenotyping.

Additionally, the book presents basic and clinical data on immunoresistance and glycosylation. This book is a valuable source for cancer researchers, medical doctors, clinicians and members of the biomedical field who must understand certain mechanisms to fight cancer that is resistant to immunotherapy.

Provides basic and clinical evidence based on molecular interactions and clinical studies to address the risks and benefits of cancer immunotherapy Presents the results of new immunotherapy trials, discussing the state-of-the-art in different types of cancer Discusses targeted therapies approved by the FDA, along with therapies with clinical potential used in basic studies

Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives provides high level knowledge on detailed mechanisms of actions and biological interactions of different immune drugs, with an aim of offering researchers and clinicians cutting-edge therapies to overcome drug resistance. The book explains the latest immunotherapies for different types of cancer, helping users carry out research projects or create alternatives for drug development in the pharmaceutical industry. Topics discussed include the relationship between immunotherapy and macrophages, immune checkpoints in different types of cancer, immune cocktails in solid tumors, and immune-phenotyping.Additionally, the book presents basic and clinical data on immunoresistance and glycosylation. This book is a valuable source for cancer researchers, medical doctors, clinicians and members of the biomedical field who must understand certain mechanisms to fight cancer that is resistant to immunotherapy.- Provides basic and clinical evidence based on molecular interactions and clinical studies to address the risks and benefits of cancer immunotherapy- Presents the results of new immunotherapy trials, discussing the state-of-the-art in different types of cancer- Discusses targeted therapies approved by the FDA, along with therapies with clinical potential used in basic studies

This book is a valuable source for clinical researchers, clinicians, and people in the biomedical field who want to understand the mechanisms of a very important biological factor in disease: sex. This book addresses the function of different signaling pathways, the modification of the metabolism of the cells as well as chemical compounds with estrogenic activity that are involved in the generation of gender differences in disease. The book is intended to broaden the comprehension of sexual dimorphism and its molecular mechanisms, mainly during human pathologies. It is significant to people interested in an update on sex differences in health and disease, and explains the latest sex-associated factors for different types of diseases. It also delves into the advantages of modifying metabolisms in order to obtain potential strategies for restoring the function of effector immune cells.

The aim of this book, The Innate Immune System in Health and Disease: From the Lab Bench Work to Its Clinical Implications. Volume 1, is to provide updated information to scientists and clinicians that is valuable in their quest to gather information, carry out new investigations, and develop novel drugs that are more effective and do not cause adverse effects targeting the innate immune system. This book is of high priority to people interested in an update on innate immunity. Volume 1 examines the participation of innate immunity in diseases such as infections by viruses, cancer, or parasites. Specifically, this volume discusses innate immunity as it relates to chronic HIV infection, type 2 diabetes, and SARS-CoV-2, as well as its relationship with vitamin D. The dual role of neutrophils in cancer development and the plasticity of natural killer cells are investigated. Also, the immune response to infections from helminth and Toxoplasma gondii are described. The Innate Immune System in Health and Disease: From the Lab Bench Work to its Clinical Implications. Volume 1 promises to be a must-have book for all people who want to know about the role of the basic functioning of the innate immune system in several diseases of actual relevance to human health.

The aim of this book, The Innate Immune System in Health and Disease: From the Lab Bench Work to Its Clinical Implications. Volume 2, is to provide updated information to scientists and clinicians that is valuable in their quest to gather information, carry out new investigations, or to check on clinical implications of the innate immune system function during disease. This book is of high priority to people interested in an update on innate immunity. Volume 2 examines topics such as the participation of the innate immune system in homeostasis and in the pathogenesis of chronic inflammatory diseases, the innate immune response and its modulation by sex hormones during chronic lung inflammation, and asthma beyond adaptive immunity. Moreover, the role of TLRS during arthritis rheumatoid onset and development is discussed as well as the modulation of the innate immune system by extracellular vesicles. Furthermore, a novel strategy to interrupt the transmission of diseases by mosquitoes and the modulation of the innate immune system by the endocrine disrupting compounds bisphenol A (BPA) and phthalates are discussed. The Innate Immune System in Health and Disease: From the Lab Bench Work to its Clinical Implications. Volume 2 promises to be a must-have book for all people who want to know about the role of the basic functioning of the innate immune system in several diseases of actual relevance to human health.