Two groups of volunteers having no eye disease were examined electro-oculo- graphically twice at ten minute intervals. One group smoked in the break, one didn't. In the non-smoking group there are a number of significant correlations between the tested parameters in the dark-period and in the light-period, which could not be found to the same degree in the smoking group. The fact that there were differences between the two groups-even though not interpretable systematicaIly-suggests, that smoking influences physiological processes in the EOG. In the second period of the test, a parallelism in the course of EOG and EEG was observed, the EEG-changes, however, are interpreted more psychologically than pharmacologicaIly. REFERENCES HAASE, E. & MUELLER, W. Messbare Beeinflussung des EOG durch Zigarettenrauchen1 Klin. Mbl. Augenhk. Bd. 158:677 (1971). HAGER, H. Thrombangiitis obliterans und Auge. Klin. Mbl. Augenhk. Bd. 114:238 (1949). HAUSER, H., SCHWARZE, B. E., ROTH, G. & BICKFORD, R. G. Electroencephalographic changes related to smoking. EEG clin. Neurophysiol. Vol. 10:576P (1958). HEIMBOCK. Wien. klin. Wschr. Bd. 73:529 (1961). HOLLWICH, F., JUNEMANN, G. & DAMASKE, E. Auge.In: Nikotin. Edited by Schievelbein. H. Georg Thieme Verlag, Stuttgart (1968). HOMER, L. D. & KOLDER, H. Mathematical model of oscillations in human corneo-retinal potential. Pflugers Arch. ges. Physiol. 287 :197 (1966). KOLDER H. Spontane und experimentelle Anderungen des Bestandpotentials des menschlichen Auges. P{lugerrs Arch. ges. Physiol. 268:258 (1959). KOLDER, H. E. & HOCHGESAND, P. Empirical Model of Electro-Oculogram. Doc. Ophtha!. (1972) in press.

Professor GOSTA KARPE GOSTA KARPE was born in Vadstena, Sweden, 1908. His medical education started in 1927 at the Karolinska Institute in Stockholm During his study he worked parttime in the department of physiology. KARPE served as a resident in the ophthalmological department of Serafiner lasarettet from 1937 till 1941. That year, the university eye clinic was transferred to the newly built Karolinska Sjukhuset, where KARPE became assistant-head of the out-patient department, and lecturer in ophthalmology. In 1949 he was appoin­ ted professor in ophthalmology at the Karolinska Institute and head of the department of ophthalmology at Karolinska Sjukhuset. KARPE received his doctor degree in 1945 upon completion of his thesis: 'The basis of clinical electroretinography'. This original work opened up a completely new field of clinical investigation. Soon Swedish and foreign pupils flocked into his department to study his new method, a technique at present accepted as an indispensable tool in ophthalmic practice. Since 1945 his work as well as that of his pupils have been devoted mainly to this field of research.

Professor GOSTA KARPE GOSTA KARPE was born in Vadstena, Sweden, 1908. His medical education started in 1927 at the Karolinska Institute in Stockholm During his study he worked parttime in the department of physiology. KARPE served as a resident in the ophthalmological department of Serafiner lasarettet from 1937 till 1941. That year, the university eye clinic was transferred to the newly built Karolinska Sjukhuset, where KARPE became assistant-head of the out-patient department, and lecturer in ophthalmology. In 1949 he was appoin­ ted professor in ophthalmology at the Karolinska Institute and head of the department of ophthalmology at Karolinska Sjukhuset. KARPE received his doctor degree in 1945 upon completion of his thesis: ''The basis of clinical electroretinography''. This original work opened up a completely new field of clinical investigation. Soon Swedish and foreign pupils flocked into his department to study his new method, a technique at present accepted as an indispensable tool in ophthalmic practice. Since 1945 his work as well as that of his pupils have been devoted mainly to this field of research.

Two groups of volunteers having no eye disease were examined electro-oculo- graphically twice at ten minute intervals. One group smoked in the break, one didn't. In the non-smoking group there are a number of significant correlations between the tested parameters in the dark-period and in the light-period, which could not be found to the same degree in the smoking group. The fact that there were differences between the two groups-even though not interpretable systematicaIly-suggests, that smoking influences physiological processes in the EOG. In the second period of the test, a parallelism in the course of EOG and EEG was observed, the EEG-changes, however, are interpreted more psychologically than pharmacologicaIly. REFERENCES HAASE, E. & MUELLER, W. Messbare Beeinflussung des EOG durch Zigarettenrauchen1 Klin. Mbl. Augenhk. Bd. 158:677 (1971). HAGER, H. Thrombangiitis obliterans und Auge. Klin. Mbl. Augenhk. Bd. 114:238 (1949). HAUSER, H., SCHWARZE, B. E., ROTH, G. & BICKFORD, R. G. Electroencephalographic changes related to smoking. EEG clin. Neurophysiol. Vol. 10:576P (1958). HEIMBOCK. Wien. klin. Wschr. Bd. 73:529 (1961). HOLLWICH, F., JUNEMANN, G. & DAMASKE, E. Auge.In: Nikotin. Edited by Schievelbein. H. Georg Thieme Verlag, Stuttgart (1968). HOMER, L. D. & KOLDER, H. Mathematical model of oscillations in human corneo-retinal potential. Pflugers Arch. ges. Physiol. 287 :197 (1966). KOLDER H. Spontane und experimentelle Anderungen des Bestandpotentials des menschlichen Auges. P{lugerrs Arch. ges. Physiol. 268:258 (1959). KOLDER, H. E. & HOCHGESAND, P. Empirical Model of Electro-Oculogram. Doc. Ophtha!. (1972) in press.

Professor GOSTA KARPE GOSTA KARPE was born in Vadstena, Sweden, 1908. His medical education started in 1927 at the Karolinska Institute in Stockholm During his study he worked parttime in the department of physiology. KARPE served as a resident in the ophthalmological department of Serafiner lasarettet from 1937 till 1941. That year, the university eye clinic was transferred to the newly built Karolinska Sjukhuset, where KARPE became assistant-head of the out-patient department, and lecturer in ophthalmology. In 1949 he was appoin­ ted professor in ophthalmology at the Karolinska Institute and head of the department of ophthalmology at Karolinska Sjukhuset. KARPE received his doctor degree in 1945 upon completion of his thesis: 'The basis of clinical electroretinography'. This original work opened up a completely new field of clinical investigation. Soon Swedish and foreign pupils flocked into his department to study his new method, a technique at present accepted as an indispensable tool in ophthalmic practice. Since 1945 his work as well as that of his pupils have been devoted mainly to this field of research.

Professor GOSTA KARPE GOSTA KARPE was born in Vadstena, Sweden, 1908. His medical education started in 1927 at the Karolinska Institute in Stockholm During his study he worked parttime in the department of physiology. KARPE served as a resident in the ophthalmological department of Serafiner lasarettet from 1937 till 1941. That year, the university eye clinic was transferred to the newly built Karolinska Sjukhuset, where KARPE became assistant-head of the out-patient department, and lecturer in ophthalmology. In 1949 he was appoin­ ted professor in ophthalmology at the Karolinska Institute and head of the department of ophthalmology at Karolinska Sjukhuset. KARPE received his doctor degree in 1945 upon completion of his thesis: ''The basis of clinical electroretinography''. This original work opened up a completely new field of clinical investigation. Soon Swedish and foreign pupils flocked into his department to study his new method, a technique at present accepted as an indispensable tool in ophthalmic practice. Since 1945 his work as well as that of his pupils have been devoted mainly to this field of research.