Jun Liao – författare

This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students. 

This book covers up-to-date knowledge of how designs found in nature use tissue hierarchies to achieve optimal functions, and how these principles are applied in bioengineering. The hierarchy-based multiscale approach has the potential to drive novel biomaterial designs, advance tissue engineering and regeneration, assist in tissue-function integration, improve high-fidelity computational modeling aided by machine learning, and enhance the development of innovative characterization tools and methodologies. This book presents the latest high-impact research achievements in bioengineered and natural hierarchical systems within a clinical context. Our aim is two-fold: (i) to emphasize the importance of integrating and bridging bioengineering designs at various tissue hierarchical levels and (ii) to foster dialogue and collaboration among bioengineers, biomechanists, and clinicians.