Kanwal Rehman – författare

Biochemistry of Drug Metabolizing Enzymes: Trends and Challenges is a complete and well-integrated reference on their mechanisms of action, their role in diseases, agents responsible for their deactivation, and their malfunction. Chapters explain the biochemistry of DMEs, including biochemical activation, functions, computational approaches, different contaminants on the action and function of DMEs, and describe the importance of DMEs in the drug development process. Conditions covered include metabolic diseases, cardiovascular diseases, neurological diseases, physiological diseases, xenobiotics and inflammatory responses, and their contribution in the malfunctioning of drug metabolizing enzymes.

This book is the perfect resource for pharmacology and biochemistry researchers to understand the principles of DMEs. Researchers in the corporate environment will also benefit from the comprehensive list of diseases associated with malfunction of DMEs.

Pharmaceutical Biotechnology in Drug Development summarizes key concepts and the latest developments of biotechnology applied to the development of biopharmaceuticals. Chapters present a comprehensive collection of introductory biotechnology technologies and their modern concepts and cover pharmacokinetic and pharmacodynamic behavior of biopharmaceuticals and modification techniques of amino acids and nucleic acid. Other sections focus on topics such as gene therapy, immunological preparations and nanoparticles which are the major contributions of pharmaceutical biotechnology. Final chapters discuss emerging techniques in the field of pharmaceutical biotechnology to meet current patient and health care demand.

This book is an essential reference useful for pharmaceutical scientists, clinicians and academic researchers who want easy access to up-to-date practices of pharmaceutical biotechnology. Corporate researchers will also benefit from this book's succinct and objective content structure.

Recent advances in the pharmaceutical sciences and biotechnology have facilitated the production, design, formulation and use of various types of pharmaceuticals and biopharmaceuticals. This book provides detailed information on the background, basic principles, and components of techniques used for the analysis of pharmaceuticals and biopharmaceuticals. Focusing on those analytical techniques that are most frequently used for pharmaceuticals, it classifies them into three major sections and 19 chapters, each of which discusses a respective technique in detail. Chiefly intended for graduate students in the pharmaceutical sciences, the book will familiarize them with the components, working principles and practical applications of these indispensable analytical techniques.

This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics. 

This 2nd edition of the comprehensive resource on pharmaceutical analysis and analytical techniques builds upon the success of its first edition by incorporating updated methodologies, expanded content, and fresh insights into modern practices. Designed for students, researchers, and industry professionals alike, the book bridges theoretical principles with practical applications, covering both classical methods and innovative approaches across spectrophotometry, chromatography, mass spectrometry, and thermal analysis.

Detailed chapters elucidate method development, instrumentation, quality control, and regulatory compliance, while enriched case studies and examples from environmental science, biomedical research, and materials science illustrate real-world applications. New sections highlight the integration of miniaturized instruments, hyphenated techniques, and computational tools including machine learning and cloud-based analytics. Enhanced diagrams, tables, and summaries further facilitate the understanding of complex analytical concepts.

This edition not only reinforces essential foundational knowledge but also equips readers with advanced practical skills to meet evolving challenges in pharmaceutical research and quality assurance. Whether you are seeking a solid academic grounding or aiming to adopt cutting-edge techniques, this book provides an indispensable guide to mastering contemporary pharmaceutical analysis and the future of analytical chemistry. With its rigorous and accessible approach, this book serves as an essential reference that inspires innovation in analytical sciences.